ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 38/249 145/7206 8.92424435798e-24 ko05322 Systemic lupus erythematosus 36/249 151/7206 4.941217538e-21 ko05034 Alcoholism 34/249 238/7206 8.46810015922e-13 ko03008 Ribosome biogenesis in eukaryotes 20/249 79/7206 1.18469744064e-12 ko04111 Cell cycle - yeast 18/249 90/7206 1.09514265987e-09 ko04110 Cell cycle 22/249 145/7206 3.7175042322e-09 ko05203 Viral carcinogenesis 31/249 277/7206 4.87463212302e-09 ko03440 Homologous recombination 10/249 41/7206 8.83189559176e-07 ko03013 RNA transport 20/249 166/7206 9.50695027998e-07 ko04113 Meiosis - yeast 12/249 70/7206 3.97921221515e-06 ko03018 RNA degradation 13/249 84/7206 5.13984586679e-06 ko04151 PI3K-Akt signaling pathway 1/249 390/7206 2.2058142232e-05 ko03020 RNA polymerase 6/249 29/7206 0.000389754611479 ko04144 Endocytosis 2/249 342/7206 0.00071974619643 ko04114 Oocyte meiosis 13/249 139/7206 0.000987003309276 ko04015 Rap1 signaling pathway 1/249 278/7206 0.00111949484379 ko04010 MAPK signaling pathway 2/249 321/7206 0.00150002300534 ko04810 Regulation of actin cytoskeleton 1/249 264/7206 0.00160955684526 ko03460 Fanconi anemia pathway 7/249 51/7206 0.00170584859155 ko05202 Transcriptional misregulation in cancer 15/249 188/7206 0.00332709194617 ko00240 Pyrimidine metabolism 10/249 110/7206 0.00457072083247 ko04014 Ras signaling pathway 2/249 279/7206 0.00645481082694 ko04022 cGMP-PKG signaling pathway 1/249 216/7206 0.00721398316889 ko03410 Base excision repair 5/249 38/7206 0.00935080276454 ko04060 Cytokine-cytokine receptor interaction 1/249 191/7206 0.0151060098747 ko04072 Phospholipase D signaling pathway 1/249 197/7206 0.0154730342246 ko04062 Chemokine signaling pathway 1/249 201/7206 0.0160989777845 ko03022 Basal transcription factors 5/249 44/7206 0.017122360155 ko05166 HTLV-I infection 18/249 292/7206 0.0200152474178 ko05200 Pathways in cancer 8/249 492/7206 0.0203577766151 ko03420 Nucleotide excision repair 5/249 46/7206 0.0204469419345 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/249 182/7206 0.0219245144799 ko04360 Axon guidance 2/249 233/7206 0.0259994438307 ko05205 Proteoglycans in cancer 3/249 271/7206 0.0262298564026 ko04914 Progesterone-mediated oocyte maturation 8/249 104/7206 0.0270368850092 ko05217 Basal cell carcinoma 6/249 68/7206 0.0294179397161 ko04910 Insulin signaling pathway 1/249 172/7206 0.0318107823837 ko05161 Hepatitis B 1/249 173/7206 0.0319955745944 ko04217 Necroptosis 12/249 178/7206 0.0334575368589 ko03430 Mismatch repair 3/249 22/7206 0.0386528510456 ko03030 DNA replication 4/249 38/7206 0.0409560626669 ko03015 mRNA surveillance pathway 7/249 93/7206 0.0413768460015 ko04115 p53 signaling pathway 6/249 74/7206 0.042055869076 ko04140 Autophagy - animal 1/249 164/7206 0.0468796352835