ko pathway ratio_in_study ratio_in_pop p_value ko04212 Longevity regulating pathway - worm 3/21 87/7206 0.00193195567489 ko04211 Longevity regulating pathway 3/21 123/7206 0.00515629618898 ko04922 Glucagon signaling pathway 3/21 128/7206 0.00576246344892 ko04020 Calcium signaling pathway 4/21 265/7206 0.00652546732193 ko05205 Proteoglycans in cancer 4/21 271/7206 0.00705929667832 ko04024 cAMP signaling pathway 4/21 279/7206 0.00781556226894 ko04624 Toll and Imd signaling pathway 2/21 49/7206 0.0087600197184 ko04722 Neurotrophin signaling pathway 3/21 160/7206 0.0106513456326 ko04725 Cholinergic synapse 3/21 160/7206 0.0106513456326 ko04152 AMPK signaling pathway 3/21 161/7206 0.0108333145934 ko00290 Valine, leucine and isoleucine biosynthesis 1/21 4/7206 0.0116085008985 ko04068 FoxO signaling pathway 3/21 167/7206 0.0119634358706 ko04910 Insulin signaling pathway 3/21 172/7206 0.0129557472933 ko05213 Endometrial cancer 2/21 62/7206 0.0137694654485 ko05223 Non-small cell lung cancer 2/21 66/7206 0.0155102396092 ko05214 Glioma 2/21 79/7206 0.0217787044916 ko04213 Longevity regulating pathway - multiple species 2/21 86/7206 0.0255229158758 ko04917 Prolactin signaling pathway 2/21 87/7206 0.0260779972923 ko05031 Amphetamine addiction 2/21 91/7206 0.0283475748135 ko04360 Axon guidance 3/21 233/7206 0.0288726714369 ko05100 Bacterial invasion of epithelial cells 2/21 99/7206 0.033116851546 ko04720 Long-term potentiation 2/21 99/7206 0.033116851546 ko01521 EGFR tyrosine kinase inhibitor resistance 2/21 106/7206 0.0375318118981 ko04012 ErbB signaling pathway 2/21 109/7206 0.039490427114 ko00770 Pantothenate and CoA biosynthesis 1/21 14/7206 0.0400709034294 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 1/21 15/7206 0.0428738109696 ko04014 Ras signaling pathway 3/21 279/7206 0.045597324189 ko04750 Inflammatory mediator regulation of TRP channels 2/21 122/7206 0.0484163501882 ko04066 HIF-1 signaling pathway 2/21 123/7206 0.0491313924035