ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	34/440	80/7206	4.93295785494e-21
ko05033	Nicotine addiction	20/440	56/7206	3.43710389634e-11
ko04728	Dopaminergic synapse	36/440	185/7206	3.00280689745e-10
ko04724	Glutamatergic synapse	31/440	152/7206	1.63477602391e-09
ko04727	GABAergic synapse	24/440	110/7206	3.03528153174e-08
ko04911	Insulin secretion	24/440	117/7206	1.06400007764e-07
ko05032	Morphine addiction	23/440	110/7206	1.36141272183e-07
ko04713	Circadian entrainment	25/440	136/7206	5.32182298321e-07
ko04723	Retrograde endocannabinoid signaling	29/440	175/7206	6.46551551544e-07
ko04725	Cholinergic synapse	27/440	160/7206	1.0991338015e-06
ko04966	Collecting duct acid secretion	10/440	26/7206	1.42492349623e-06
ko04024	cAMP signaling pathway	36/440	279/7206	1.64956489377e-05
ko04514	Cell adhesion molecules (CAMs)	21/440	130/7206	3.44451401559e-05
ko04261	Adrenergic signaling in cardiomyocytes	28/440	205/7206	7.44821287326e-05
ko05110	Vibrio cholerae infection	13/440	63/7206	8.64912907606e-05
ko04080	Neuroactive ligand-receptor interaction	46/440	423/7206	9.40490775405e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/440	14/7206	9.87458592379e-05
ko04744	Phototransduction	9/440	36/7206	0.00023262656746
ko05203	Viral carcinogenesis	4/440	277/7206	0.000266279553437
ko05030	Cocaine addiction	13/440	73/7206	0.000407393654711
ko04970	Salivary secretion	15/440	95/7206	0.000578332844954
ko04060	Cytokine-cytokine receptor interaction	2/440	191/7206	0.0010297464416
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/440	92/7206	0.00126894950658
ko04964	Proximal tubule bicarbonate reclamation	7/440	29/7206	0.00145246788629
ko04720	Long-term potentiation	14/440	99/7206	0.00258966379512
ko04010	MAPK signaling pathway	33/440	321/7206	0.00270628696538
ko04120	Ubiquitin mediated proteolysis	1/440	138/7206	0.00330001690257
ko04972	Pancreatic secretion	15/440	111/7206	0.00377371300227
ko05205	Proteoglycans in cancer	6/440	271/7206	0.00403295273281
ko05014	Amyotrophic lateral sclerosis (ALS)	11/440	74/7206	0.0049274409133
ko04360	Axon guidance	25/440	233/7206	0.0050754201391
ko04621	NOD-like receptor signaling pathway	2/440	157/7206	0.00610641274536
ko05168	Herpes simplex infection	3/440	182/7206	0.00689750784214
ko04730	Long-term depression	11/440	78/7206	0.00736805637042
ko05322	Systemic lupus erythematosus	2/440	151/7206	0.0087505491127
ko04726	Serotonergic synapse	16/440	137/7206	0.010693386914
ko04391	Hippo signaling pathway - fly	12/440	90/7206	0.0115308961525
ko04921	Oxytocin signaling pathway	22/440	209/7206	0.0117223738684
ko04071	Sphingolipid signaling pathway	18/440	162/7206	0.0119325959129
ko05031	Amphetamine addiction	12/440	91/7206	0.0120670839252
ko03040	Spliceosome	2/440	145/7206	0.0125212419054
ko03013	RNA transport	3/440	166/7206	0.0132248253393
ko05164	Influenza A	3/440	167/7206	0.0132658670282
ko04141	Protein processing in endoplasmic reticulum	4/440	184/7206	0.0186249837583
ko04924	Renin secretion	11/440	86/7206	0.0192742750163
ko04022	cGMP-PKG signaling pathway	22/440	216/7206	0.0194960367972
ko05323	Rheumatoid arthritis	11/440	89/7206	0.0225486963427
ko01200	Carbon metabolism	2/440	128/7206	0.0241212230049
ko04745	Phototransduction - fly	6/440	38/7206	0.0261680034729
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/440	182/7206	0.0262085930531
ko04144	Endocytosis	31/440	342/7206	0.0269608105435
ko04064	NF-kappa B signaling pathway	1/440	96/7206	0.0300829094915
ko05161	Hepatitis B	4/440	173/7206	0.0347888173158
ko04510	Focal adhesion	7/440	240/7206	0.0381734616047
ko04973	Carbohydrate digestion and absorption	6/440	42/7206	0.0405796564733
ko04940	Type I diabetes mellitus	5/440	32/7206	0.0426874775988
ko04146	Peroxisome	1/440	89/7206	0.0433205707427
ko00062	Fatty acid elongation	5/440	33/7206	0.0478890901594
ko04130	SNARE interactions in vesicular transport	6/440	44/7206	0.0493546290533