ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	167/870	423/7206	1.23570528042e-50
ko04724	Glutamatergic synapse	83/870	152/7206	1.12526138281e-37
ko05033	Nicotine addiction	46/870	56/7206	2.1523495236e-33
ko05032	Morphine addiction	56/870	110/7206	1.21947256846e-23
ko04713	Circadian entrainment	63/870	136/7206	1.37106205483e-23
ko04728	Dopaminergic synapse	74/870	185/7206	1.04267285287e-22
ko04727	GABAergic synapse	53/870	110/7206	5.35673221245e-21
ko04723	Retrograde endocannabinoid signaling	67/870	175/7206	2.02693720081e-19
ko04020	Calcium signaling pathway	85/870	265/7206	1.37319298873e-18
ko04024	cAMP signaling pathway	86/870	279/7206	1.41414053332e-17
ko04725	Cholinergic synapse	60/870	160/7206	5.43026318638e-17
ko04726	Serotonergic synapse	54/870	137/7206	1.64819887636e-16
ko04720	Long-term potentiation	43/870	99/7206	3.42556203088e-15
ko05031	Amphetamine addiction	39/870	91/7206	1.15486861312e-13
ko04911	Insulin secretion	45/870	117/7206	1.67695423635e-13
ko04721	Synaptic vesicle cycle	36/870	80/7206	1.68914677375e-13
ko04921	Oxytocin signaling pathway	64/870	209/7206	3.50642383056e-13
ko04742	Taste transduction	28/870	61/7206	4.83216978876e-11
ko04261	Adrenergic signaling in cardiomyocytes	57/870	205/7206	5.6439299332e-10
ko04744	Phototransduction	19/870	36/7206	3.41892298688e-09
ko05030	Cocaine addiction	28/870	73/7206	7.32133886014e-09
ko04925	Aldosterone synthesis and secretion	34/870	105/7206	2.88030981038e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/870	74/7206	4.71667165929e-08
ko04970	Salivary secretion	31/870	95/7206	9.66889136259e-08
ko04730	Long-term depression	26/870	78/7206	6.56704480043e-07
ko04971	Gastric acid secretion	30/870	98/7206	7.42192545024e-07
ko04010	MAPK signaling pathway	69/870	321/7206	1.04700112718e-06
ko03010	Ribosome	1/870	129/7206	1.7527064052e-06
ko03040	Spliceosome	2/870	145/7206	3.50220444186e-06
ko04060	Cytokine-cytokine receptor interaction	5/870	191/7206	4.36036129334e-06
ko04972	Pancreatic secretion	31/870	111/7206	4.85387618401e-06
ko04070	Phosphatidylinositol signaling system	31/870	112/7206	5.75914204108e-06
ko05168	Herpes simplex infection	5/870	182/7206	8.7535060361e-06
ko04022	cGMP-PKG signaling pathway	47/870	216/7206	4.44438810055e-05
ko04740	Olfactory transduction	23/870	80/7206	4.44678176505e-05
ko05164	Influenza A	5/870	167/7206	5.41062982249e-05
ko04514	Cell adhesion molecules (CAMs)	32/870	130/7206	5.89493021887e-05
ko05322	Systemic lupus erythematosus	4/870	151/7206	6.5462953774e-05
ko04745	Phototransduction - fly	14/870	38/7206	7.4265884025e-05
ko04072	Phospholipase D signaling pathway	43/870	197/7206	8.5035112648e-05
ko05203	Viral carcinogenesis	14/870	277/7206	9.83802087241e-05
ko05169	Epstein-Barr virus infection	9/870	206/7206	0.000192633061696
ko04260	Cardiac muscle contraction	25/870	98/7206	0.000224614875928
ko05162	Measles	3/870	120/7206	0.000317687007787
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/870	79/7206	0.00035311413986
ko04110	Cell cycle	5/870	145/7206	0.00042597012662
ko04621	NOD-like receptor signaling pathway	6/870	157/7206	0.000458282731438
ko04141	Protein processing in endoplasmic reticulum	8/870	184/7206	0.000500567083219
ko04750	Inflammatory mediator regulation of TRP channels	28/870	122/7206	0.00063804376733
ko03013	RNA transport	7/870	166/7206	0.000661714868711
ko04540	Gap junction	29/870	128/7206	0.000824636952876
ko04612	Antigen processing and presentation	1/870	77/7206	0.00115626447416
ko05200	Pathways in cancer	39/870	492/7206	0.00256619928276
ko04120	Ubiquitin mediated proteolysis	6/870	138/7206	0.00330175145303
ko04626	Plant-pathogen interaction	7/870	18/7206	0.00348421111784
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/870	14/7206	0.00387352136505
ko04915	Estrogen signaling pathway	27/870	131/7206	0.00428873151521
ko04630	Jak-STAT signaling pathway	6/870	132/7206	0.00439344851642
ko04610	Complement and coagulation cascades	2/870	79/7206	0.00479470097889
ko03008	Ribosome biogenesis in eukaryotes	2/870	79/7206	0.00479470097889
ko04964	Proximal tubule bicarbonate reclamation	9/870	29/7206	0.00554707908704
ko05130	Pathogenic Escherichia coli infection	2/870	77/7206	0.00716128106777
ko04924	Renin secretion	19/870	86/7206	0.00723461883315
ko04360	Axon guidance	42/870	233/7206	0.00750452199218
ko05166	HTLV-I infection	21/870	292/7206	0.00760432725313
ko04146	Peroxisome	3/870	89/7206	0.00788692394017
ko00310	Lysine degradation	2/870	73/7206	0.0101299381645
ko04210	Apoptosis	11/870	180/7206	0.0104470982333
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/870	182/7206	0.0106522490318
ko05034	Alcoholism	42/870	238/7206	0.0110022471284
ko04014	Ras signaling pathway	48/870	279/7206	0.0110150957753
ko05414	Dilated cardiomyopathy	23/870	112/7206	0.0118713594289
ko00562	Inositol phosphate metabolism	19/870	89/7206	0.0126975387338
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/870	59/7206	0.0135676551612
ko04973	Carbohydrate digestion and absorption	11/870	42/7206	0.0137352283312
ko03320	PPAR signaling pathway	2/870	69/7206	0.01436813265
ko04550	Signaling pathways regulating pluripotency of stem cells	10/870	165/7206	0.0149761534654
ko05231	Choline metabolism in cancer	26/870	134/7206	0.0149792462277
ko04668	TNF signaling pathway	6/870	120/7206	0.0152601014476
ko05161	Hepatitis B	11/870	173/7206	0.0176202035252
ko04640	Hematopoietic cell lineage	2/870	64/7206	0.0203538092422
ko05222	Small cell lung cancer	4/870	89/7206	0.0216810013566
ko04912	GnRH signaling pathway	23/870	122/7206	0.0249177013531
ko04510	Focal adhesion	18/870	240/7206	0.0262162846571
ko04960	Aldosterone-regulated sodium reabsorption	10/870	41/7206	0.0262360442609
ko00240	Pyrimidine metabolism	6/870	110/7206	0.0269480602578
ko05010	Alzheimer's disease	35/870	202/7206	0.027663347414
ko05205	Proteoglycans in cancer	21/870	271/7206	0.0282155772583
ko04140	Autophagy - animal	11/870	164/7206	0.0291408784991
ko04330	Notch signaling pathway	2/870	62/7206	0.029303377027
ko04657	IL-17 signaling pathway	4/870	87/7206	0.0299586980874
ko05133	Pertussis	4/870	87/7206	0.0299586980874
ko04966	Collecting duct acid secretion	7/870	26/7206	0.0305054596731
ko05140	Leishmaniasis	3/870	75/7206	0.0305522702306
ko04930	Type II diabetes mellitus	12/870	54/7206	0.0328875369817
ko05224	Breast cancer	12/870	174/7206	0.0333958134611
ko00071	Fatty acid degradation	1/870	45/7206	0.0374492297176
ko03420	Nucleotide excision repair	1/870	46/7206	0.0379518042988
ko04150	mTOR signaling pathway	13/870	184/7206	0.0381125051783
ko05131	Shigellosis	4/870	82/7206	0.0406567265649
ko05410	Hypertrophic cardiomyopathy (HCM)	19/870	100/7206	0.0427958456332
ko04214	Apoptosis - fly	3/870	72/7206	0.0428729545367
ko04918	Thyroid hormone synthesis	17/870	86/7206	0.043145823327
ko04371	Apelin signaling pathway	30/870	177/7206	0.0473075007115
ko04217	Necroptosis	13/870	178/7206	0.0474492408438
ko04350	TGF-beta signaling pathway	6/870	103/7206	0.047680222379
ko04666	Fc gamma R-mediated phagocytosis	22/870	122/7206	0.048982119801
ko05110	Vibrio cholerae infection	13/870	63/7206	0.0491741295063
ko04071	Sphingolipid signaling pathway	28/870	162/7206	0.0498346584034