ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04060	Cytokine-cytokine receptor interaction	48/550	191/7206	4.49337201286e-14
ko04380	Osteoclast differentiation	31/550	134/7206	1.40406244285e-08
ko00120	Primary bile acid biosynthesis	10/550	20/7206	5.67687370539e-07
ko05164	Influenza A	32/550	167/7206	8.57029348887e-07
ko04672	Intestinal immune network for IgA production	12/550	37/7206	1.09145255262e-05
ko05321	Inflammatory bowel disease (IBD)	15/550	56/7206	1.23477047802e-05
ko04621	NOD-like receptor signaling pathway	28/550	157/7206	2.06655237701e-05
ko04064	NF-kappa B signaling pathway	20/550	96/7206	2.82370371498e-05
ko00140	Steroid hormone biosynthesis	12/550	41/7206	3.50603944016e-05
ko05140	Leishmaniasis	17/550	75/7206	3.60136599571e-05
ko04659	Th17 cell differentiation	21/550	106/7206	3.96957024819e-05
ko04650	Natural killer cell mediated cytotoxicity	19/550	97/7206	0.000107877145034
ko00350	Tyrosine metabolism	10/550	33/7206	0.000114440405621
ko03040	Spliceosome	1/550	145/7206	0.000204037544376
ko05145	Toxoplasmosis	22/550	126/7206	0.000229931062155
ko04610	Complement and coagulation cascades	16/550	79/7206	0.00024939506503
ko05150	Staphylococcus aureus infection	10/550	36/7206	0.000255000391386
ko05160	Hepatitis C	25/550	153/7206	0.000274227912963
ko05340	Primary immunodeficiency	9/550	30/7206	0.000274587746293
ko05167	Kaposi's sarcoma-associated herpesvirus infection	29/550	191/7206	0.000281691432473
ko04658	Th1 and Th2 cell differentiation	18/550	96/7206	0.000289005455321
ko05162	Measles	21/550	120/7206	0.00032125367869
ko00590	Arachidonic acid metabolism	12/550	52/7206	0.000421655959555
ko04217	Necroptosis	27/550	178/7206	0.000491328091161
ko03010	Ribosome	1/550	129/7206	0.000651772498574
ko04666	Fc gamma R-mediated phagocytosis	20/550	122/7206	0.000902873412076
ko05168	Herpes simplex infection	27/550	182/7206	0.000913039007377
ko05323	Rheumatoid arthritis	16/550	89/7206	0.000999950113521
ko05034	Alcoholism	6/550	238/7206	0.00110138432006
ko00982	Drug metabolism - cytochrome P450	9/550	37/7206	0.00147495403041
ko03013	RNA transport	3/550	166/7206	0.00165642340262
ko00643	Styrene degradation	3/550	4/7206	0.00166880600187
ko04620	Toll-like receptor signaling pathway	17/550	100/7206	0.00168288008664
ko00592	alpha-Linolenic acid metabolism	6/550	19/7206	0.00220684478267
ko05152	Tuberculosis	26/550	187/7206	0.00291921171792
ko04662	B cell receptor signaling pathway	15/550	88/7206	0.00335073425412
ko00051	Fructose and mannose metabolism	9/550	42/7206	0.00375470294698
ko00565	Ether lipid metabolism	9/550	42/7206	0.00375470294698
ko04611	Platelet activation	23/550	163/7206	0.00397168144182
ko04710	Circadian rhythm	9/550	43/7206	0.00443538835961
ko04933	AGE-RAGE signaling pathway in diabetic complications	20/550	135/7206	0.00450539162083
ko00950	Isoquinoline alkaloid biosynthesis	4/550	10/7206	0.0048593331767
ko04668	TNF signaling pathway	18/550	120/7206	0.00486856803492
ko05320	Autoimmune thyroid disease	7/550	29/7206	0.00515316723348
ko04110	Cell cycle	3/550	145/7206	0.00655111161764
ko05133	Pertussis	14/550	87/7206	0.006744983842
ko04062	Chemokine signaling pathway	26/550	201/7206	0.00675345026037
ko00360	Phenylalanine metabolism	5/550	17/7206	0.00727313094242
ko04670	Leukocyte transendothelial migration	21/550	151/7206	0.00744321482634
ko05330	Allograft rejection	6/550	24/7206	0.00789288200797
ko04512	ECM-receptor interaction	13/550	79/7206	0.00818071267736
ko05161	Hepatitis B	23/550	173/7206	0.00832361025049
ko04640	Hematopoietic cell lineage	11/550	64/7206	0.00840431733337
ko04660	T cell receptor signaling pathway	18/550	124/7206	0.00903127465087
ko05204	Chemical carcinogenesis	9/550	48/7206	0.00938769649137
ko05332	Graft-versus-host disease	5/550	18/7206	0.00945026374233
ko03015	mRNA surveillance pathway	1/550	93/7206	0.00946293969541
ko00980	Metabolism of xenobiotics by cytochrome P450	8/550	40/7206	0.00950062653184
ko05131	Shigellosis	13/550	82/7206	0.0101484219165
ko04623	Cytosolic DNA-sensing pathway	8/550	41/7206	0.011038072744
ko04723	Retrograde endocannabinoid signaling	5/550	175/7206	0.013283639793
ko04727	GABAergic synapse	2/550	110/7206	0.016804355577
ko04390	Hippo signaling pathway	6/550	188/7206	0.017109020044
ko04630	Jak-STAT signaling pathway	18/550	132/7206	0.0186376256857
ko05418	Fluid shear stress and atherosclerosis	22/550	173/7206	0.0189530411248
ko05144	Malaria	8/550	45/7206	0.0190583077872
ko05231	Choline metabolism in cancer	18/550	134/7206	0.0195559076193
ko04072	Phospholipase D signaling pathway	24/550	197/7206	0.0200883664742
ko00564	Glycerophospholipid metabolism	14/550	99/7206	0.0209468391737
ko04310	Wnt signaling pathway	6/550	181/7206	0.0226822071611
ko04622	RIG-I-like receptor signaling pathway	10/550	62/7206	0.0251208001482
ko04068	FoxO signaling pathway	21/550	167/7206	0.0252571210389
ko05142	Chagas disease (American trypanosomiasis)	17/550	130/7206	0.0281329177716
ko05224	Breast cancer	6/550	174/7206	0.030102141036
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	2/550	4/7206	0.0314561853007
ko04137	Mitophagy - animal	12/550	82/7206	0.0321861586935
ko04120	Ubiquitin mediated proteolysis	4/550	138/7206	0.033642358634
ko04960	Aldosterone-regulated sodium reabsorption	7/550	41/7206	0.0336511567415
ko00480	Glutathione metabolism	9/550	55/7206	0.0346533527378
ko05310	Asthma	4/550	17/7206	0.0359387128071
ko03320	PPAR signaling pathway	10/550	69/7206	0.039469546025
ko04657	IL-17 signaling pathway	12/550	87/7206	0.0397087489374
ko01524	Platinum drug resistance	11/550	76/7206	0.0454467541411
ko04664	Fc epsilon RI signaling pathway	11/550	77/7206	0.0468612599741
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/550	5/7206	0.0498034242027
ko00281	Geraniol degradation	2/550	5/7206	0.0498034242027