ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04610	Complement and coagulation cascades	39/476	79/7206	9.77044898945e-26
ko04974	Protein digestion and absorption	29/476	96/7206	1.26337267721e-12
ko04975	Fat digestion and absorption	17/476	35/7206	9.82016724145e-12
ko01200	Carbon metabolism	28/476	128/7206	1.1354296166e-08
ko04976	Bile secretion	21/476	80/7206	2.77906205605e-08
ko00260	Glycine, serine and threonine metabolism	16/476	48/7206	3.21127284039e-08
ko04977	Vitamin digestion and absorption	11/476	22/7206	3.38064635003e-08
ko04978	Mineral absorption	14/476	40/7206	1.17348594687e-07
ko00010	Glycolysis / Gluconeogenesis	19/476	74/7206	1.8837766594e-07
ko00983	Drug metabolism - other enzymes	13/476	42/7206	1.67841541464e-06
ko00620	Pyruvate metabolism	13/476	46/7206	5.2406425876e-06
ko03320	PPAR signaling pathway	16/476	69/7206	7.44862363342e-06
ko00500	Starch and sucrose metabolism	11/476	35/7206	9.08290043178e-06
ko04950	Maturity onset diabetes of the young	10/476	29/7206	9.19363778315e-06
ko04973	Carbohydrate digestion and absorption	12/476	42/7206	1.070302509e-05
ko05150	Staphylococcus aureus infection	11/476	36/7206	1.23112334048e-05
ko00630	Glyoxylate and dicarboxylate metabolism	11/476	38/7206	2.18480765382e-05
ko04922	Glucagon signaling pathway	22/476	128/7206	2.79477270739e-05
ko05166	HTLV-I infection	4/476	292/7206	3.10311087399e-05
ko00380	Tryptophan metabolism	12/476	50/7206	7.22819517675e-05
ko04614	Renin-angiotensin system	7/476	18/7206	8.81094993538e-05
ko01230	Biosynthesis of amino acids	16/476	85/7206	0.000114448884113
ko00330	Arginine and proline metabolism	13/476	61/7206	0.000135466408841
ko04360	Axon guidance	3/476	233/7206	0.000144894183765
ko00040	Pentose and glucuronate interconversions	8/476	26/7206	0.000184709968892
ko04920	Adipocytokine signaling pathway	16/476	89/7206	0.000200837887126
ko00980	Metabolism of xenobiotics by cytochrome P450	10/476	40/7206	0.000201112387714
ko00052	Galactose metabolism	9/476	33/7206	0.000204851252488
ko03013	RNA transport	1/476	166/7206	0.000215067028069
ko05204	Chemical carcinogenesis	11/476	48/7206	0.000224434065483
ko00680	Methane metabolism	9/476	34/7206	0.000262553280336
ko00830	Retinol metabolism	10/476	42/7206	0.000309772823425
ko00591	Linoleic acid metabolism	7/476	22/7206	0.000374390083424
ko04964	Proximal tubule bicarbonate reclamation	8/476	29/7206	0.000425535742004
ko04144	Endocytosis	8/476	342/7206	0.000468190317146
ko04310	Wnt signaling pathway	2/476	181/7206	0.000685713831657
ko00270	Cysteine and methionine metabolism	10/476	47/7206	0.000809001886144
ko00340	Histidine metabolism	7/476	25/7206	0.000887257794335
ko05200	Pathways in cancer	16/476	492/7206	0.000961838654499
ko03040	Spliceosome	1/476	145/7206	0.00102326438706
ko04110	Cell cycle	1/476	145/7206	0.00102326438706
ko00350	Tyrosine metabolism	8/476	33/7206	0.0010892457947
ko00140	Steroid hormone biosynthesis	9/476	41/7206	0.00115917930269
ko04062	Chemokine signaling pathway	3/476	201/7206	0.00125799061542
ko04972	Pancreatic secretion	17/476	111/7206	0.0013798936259
ko04120	Ubiquitin mediated proteolysis	1/476	138/7206	0.00148182338117
ko00020	Citrate cycle (TCA cycle)	8/476	35/7206	0.00164302494246
ko04146	Peroxisome	14/476	89/7206	0.00193192460536
ko05034	Alcoholism	5/476	238/7206	0.00206313179151
ko00982	Drug metabolism - cytochrome P450	8/476	37/7206	0.00239880174775
ko00053	Ascorbate and aldarate metabolism	6/476	22/7206	0.00241552166176
ko04141	Protein processing in endoplasmic reticulum	3/476	184/7206	0.00242423758962
ko04390	Hippo signaling pathway	3/476	188/7206	0.00248811703312
ko00561	Glycerolipid metabolism	11/476	63/7206	0.00248933342127
ko00232	Caffeine metabolism	3/476	5/7206	0.00259050580484
ko04010	MAPK signaling pathway	9/476	321/7206	0.00270044002442
ko05203	Viral carcinogenesis	7/476	277/7206	0.00287631479023
ko04660	T cell receptor signaling pathway	1/476	124/7206	0.00314555934918
ko02010	ABC transporters	8/476	39/7206	0.00340296460258
ko05169	Epstein-Barr virus infection	4/476	206/7206	0.00387093335881
ko00030	Pentose phosphate pathway	7/476	32/7206	0.00415436973627
ko04724	Glutamatergic synapse	2/476	152/7206	0.00426052996471
ko04666	Fc gamma R-mediated phagocytosis	1/476	122/7206	0.00476858416308
ko05161	Hepatitis B	3/476	173/7206	0.00480703346216
ko04723	Retrograde endocannabinoid signaling	3/476	175/7206	0.00488441283434
ko05206	MicroRNAs in cancer	3/476	177/7206	0.00503301216805
ko04152	AMPK signaling pathway	20/476	161/7206	0.00565196941533
ko00640	Propanoate metabolism	7/476	34/7206	0.00592225759189
ko00710	Carbon fixation in photosynthetic organisms	6/476	27/7206	0.00723351638672
ko04216	Ferroptosis	8/476	44/7206	0.00733731339904
ko00120	Primary bile acid biosynthesis	5/476	20/7206	0.00832887688283
ko04114	Oocyte meiosis	2/476	139/7206	0.00855855644471
ko00520	Amino sugar and nucleotide sugar metabolism	9/476	55/7206	0.00925433226497
ko04722	Neurotrophin signaling pathway	3/476	160/7206	0.00938887265799
ko04727	GABAergic synapse	1/476	110/7206	0.010121348185
ko05032	Morphine addiction	1/476	110/7206	0.010121348185
ko00100	Steroid biosynthesis	5/476	21/7206	0.0103507604671
ko00250	Alanine, aspartate and glutamate metabolism	7/476	38/7206	0.0110616839149
ko00521	Streptomycin biosynthesis	3/476	8/7206	0.0124869740366
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/476	135/7206	0.0125722409192
ko04924	Renin secretion	12/476	86/7206	0.0131539397723
ko04621	NOD-like receptor signaling pathway	3/476	157/7206	0.0134173229307
ko04217	Necroptosis	4/476	178/7206	0.0135661233312
ko04520	Adherens junction	1/476	103/7206	0.0144654034296
ko04350	TGF-beta signaling pathway	1/476	103/7206	0.0144654034296
ko04072	Phospholipase D signaling pathway	5/476	197/7206	0.0186011585798
ko04014	Ras signaling pathway	9/476	279/7206	0.0187103763578
ko00051	Fructose and mannose metabolism	7/476	42/7206	0.0188490823436
ko00590	Arachidonic acid metabolism	8/476	52/7206	0.0196596359051
ko04658	Th1 and Th2 cell differentiation	1/476	96/7206	0.0207320449476
ko05100	Bacterial invasion of epithelial cells	1/476	99/7206	0.0217958769139
ko00720	Carbon fixation pathways in prokaryotes	4/476	17/7206	0.0224569520537
ko00360	Phenylalanine metabolism	4/476	17/7206	0.0224569520537
ko04931	Insulin resistance	16/476	137/7206	0.022753827679
ko00643	Styrene degradation	2/476	4/7206	0.0238932184495
ko00524	Neomycin, kanamycin and gentamicin biosynthesis	2/476	4/7206	0.0238932184495
ko05162	Measles	2/476	120/7206	0.024128526285
ko04912	GnRH signaling pathway	2/476	122/7206	0.0247763206949
ko04060	Cytokine-cytokine receptor interaction	5/476	191/7206	0.0251163537511
ko04550	Signaling pathways regulating pluripotency of stem cells	4/476	165/7206	0.0252077168735
ko00480	Glutathione metabolism	8/476	55/7206	0.0267929718668
ko04662	B cell receptor signaling pathway	1/476	88/7206	0.0296581044791
ko04657	IL-17 signaling pathway	1/476	87/7206	0.0296674697856
ko04391	Hippo signaling pathway - fly	1/476	90/7206	0.0300282006731
ko00592	alpha-Linolenic acid metabolism	4/476	19/7206	0.0329547335552
ko04015	Rap1 signaling pathway	10/476	278/7206	0.0361395902169
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/476	5/7206	0.0380950268799
ko00564	Glycerophospholipid metabolism	12/476	99/7206	0.0381358771305
ko05220	Chronic myeloid leukemia	1/476	85/7206	0.0439568954442
ko04218	Cellular senescence	5/476	177/7206	0.0442873357992
ko05210	Colorectal cancer	1/476	86/7206	0.044683324539
ko04142	Lysosome	4/476	151/7206	0.0459605848257
ko05205	Proteoglycans in cancer	10/476	271/7206	0.0460829664228
ko04914	Progesterone-mediated oocyte maturation	2/476	104/7206	0.0469099448508
ko04012	ErbB signaling pathway	2/476	109/7206	0.0483602770304