ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	93/514	423/7206	2.22852826479e-24
ko05033	Nicotine addiction	29/514	56/7206	3.12862454001e-19
ko04721	Synaptic vesicle cycle	34/514	80/7206	7.22798628156e-19
ko04724	Glutamatergic synapse	44/514	152/7206	1.66567436725e-16
ko04728	Dopaminergic synapse	47/514	185/7206	4.02220256775e-15
ko04713	Circadian entrainment	37/514	136/7206	3.95886462099e-13
ko04727	GABAergic synapse	32/514	110/7206	2.21527590576e-12
ko04024	cAMP signaling pathway	52/514	279/7206	6.54798326588e-11
ko04725	Cholinergic synapse	37/514	160/7206	7.74494063061e-11
ko04723	Retrograde endocannabinoid signaling	38/514	175/7206	3.07020684406e-10
ko05032	Morphine addiction	29/514	110/7206	3.3877257575e-10
ko04921	Oxytocin signaling pathway	42/514	209/7206	4.53760603213e-10
ko04261	Adrenergic signaling in cardiomyocytes	41/514	205/7206	8.6046125101e-10
ko04726	Serotonergic synapse	32/514	137/7206	1.17615420811e-09
ko04911	Insulin secretion	29/514	117/7206	1.64671605364e-09
ko04720	Long-term potentiation	26/514	99/7206	3.10067370942e-09
ko05031	Amphetamine addiction	24/514	91/7206	1.15633632131e-08
ko05030	Cocaine addiction	20/514	73/7206	9.79137474593e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	20/514	74/7206	1.25420027828e-07
ko04970	Salivary secretion	20/514	95/7206	8.84616646411e-06
ko04020	Calcium signaling pathway	38/514	265/7206	2.66923988095e-05
ko04010	MAPK signaling pathway	43/514	321/7206	5.0137278716e-05
ko04742	Taste transduction	14/514	61/7206	7.31110787615e-05
ko04730	Long-term depression	16/514	78/7206	9.68905651285e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/514	59/7206	0.000204528870979
ko04022	cGMP-PKG signaling pathway	31/514	216/7206	0.000216304581917
ko04966	Collecting duct acid secretion	8/514	26/7206	0.00031389732856
ko05322	Systemic lupus erythematosus	1/514	151/7206	0.000314279341928
ko04924	Renin secretion	16/514	86/7206	0.000319724676043
ko04514	Cell adhesion molecules (CAMs)	21/514	130/7206	0.000374721117205
ko04360	Axon guidance	32/514	233/7206	0.00037561006108
ko04260	Cardiac muscle contraction	17/514	98/7206	0.000496202316137
ko04971	Gastric acid secretion	17/514	98/7206	0.000496202316137
ko04540	Gap junction	20/514	128/7206	0.000744899281433
ko04745	Phototransduction - fly	9/514	38/7206	0.00111961506473
ko04626	Plant-pathogen interaction	6/514	18/7206	0.00113166955703
ko05168	Herpes simplex infection	3/514	182/7206	0.00118983102136
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/514	14/7206	0.00211023634439
ko05162	Measles	1/514	120/7206	0.0021102710011
ko03040	Spliceosome	2/514	145/7206	0.00286696687615
ko04071	Sphingolipid signaling pathway	22/514	162/7206	0.00298023919726
ko04925	Aldosterone synthesis and secretion	16/514	105/7206	0.00333715364859
ko03013	RNA transport	3/514	166/7206	0.0033628813932
ko04964	Proximal tubule bicarbonate reclamation	7/514	29/7206	0.00353671991373
ko05166	HTLV-I infection	9/514	292/7206	0.00355209916936
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/514	79/7206	0.00359128060297
ko04014	Ras signaling pathway	33/514	279/7206	0.0040283644709
ko05110	Vibrio cholerae infection	11/514	63/7206	0.00450331357646
ko04114	Oocyte meiosis	19/514	139/7206	0.00658766138495
ko04750	Inflammatory mediator regulation of TRP channels	17/514	122/7206	0.00683788973156
ko04960	Aldosterone-regulated sodium reabsorption	8/514	41/7206	0.00744708164587
ko04972	Pancreatic secretion	16/514	111/7206	0.00760522520492
ko04070	Phosphatidylinositol signaling system	16/514	112/7206	0.00792185166423
ko05203	Viral carcinogenesis	9/514	277/7206	0.00830508164243
ko04060	Cytokine-cytokine receptor interaction	5/514	191/7206	0.00978226987159
ko05010	Alzheimer's disease	24/514	202/7206	0.0119973854882
ko04015	Rap1 signaling pathway	31/514	278/7206	0.0120257840123
ko04141	Protein processing in endoplasmic reticulum	5/514	184/7206	0.0132418972854
ko05164	Influenza A	4/514	167/7206	0.0136816361127
ko05034	Alcoholism	27/514	238/7206	0.0144984676919
ko05414	Dilated cardiomyopathy	15/514	112/7206	0.0151798699939
ko04072	Phospholipase D signaling pathway	23/514	197/7206	0.0166150862461
ko04120	Ubiquitin mediated proteolysis	3/514	138/7206	0.0180564575379
ko04621	NOD-like receptor signaling pathway	4/514	157/7206	0.018196831005
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/514	182/7206	0.0182971763424
ko04657	IL-17 signaling pathway	1/514	87/7206	0.0202059243846
ko04146	Peroxisome	1/514	89/7206	0.0204619290464
ko04978	Mineral absorption	7/514	40/7206	0.0214408129985
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/514	92/7206	0.0216666298673
ko05214	Glioma	11/514	79/7206	0.0264895403597
ko04973	Carbohydrate digestion and absorption	7/514	42/7206	0.0274580198269
ko04145	Phagosome	19/514	162/7206	0.0293409633403
ko04350	TGF-beta signaling pathway	2/514	103/7206	0.0330723239842
ko04744	Phototransduction	6/514	36/7206	0.0399429487866
ko00910	Nitrogen metabolism	4/514	19/7206	0.0420494402612
ko04612	Antigen processing and presentation	1/514	77/7206	0.0425826017225
ko04668	TNF signaling pathway	3/514	120/7206	0.0471918031046