ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	91/735	145/7206	5.10769051824e-55
ko04110	Cell cycle	66/735	145/7206	1.86267329952e-28
ko03030	DNA replication	32/735	38/7206	1.54303807753e-26
ko03013	RNA transport	67/735	166/7206	3.99036756267e-25
ko03460	Fanconi anemia pathway	36/735	51/7206	6.65427603844e-25
ko04111	Cell cycle - yeast	47/735	90/7206	8.81980945989e-24
ko03440	Homologous recombination	31/735	41/7206	4.28181506358e-23
ko04113	Meiosis - yeast	35/735	70/7206	3.25387673729e-17
ko03008	Ribosome biogenesis in eukaryotes	35/735	79/7206	3.84423333904e-15
ko03430	Mismatch repair	18/735	22/7206	5.8154889214e-15
ko05322	Systemic lupus erythematosus	48/735	151/7206	1.61559417625e-13
ko03420	Nucleotide excision repair	24/735	46/7206	1.00340383666e-12
ko03410	Base excision repair	21/735	38/7206	6.19094918914e-12
ko00240	Pyrimidine metabolism	34/735	110/7206	1.40407881302e-09
ko03018	RNA degradation	28/735	84/7206	6.19308913803e-09
ko04144	Endocytosis	8/735	342/7206	1.39613865001e-08
ko03015	mRNA surveillance pathway	29/735	93/7206	1.84853993556e-08
ko05034	Alcoholism	52/735	238/7206	7.8436870391e-08
ko04024	cAMP signaling pathway	6/735	279/7206	1.6632353748e-07
ko05010	Alzheimer's disease	2/735	202/7206	1.75736550782e-07
ko04022	cGMP-PKG signaling pathway	3/735	216/7206	2.80116202009e-07
ko04060	Cytokine-cytokine receptor interaction	2/735	191/7206	3.704196829e-07
ko05203	Viral carcinogenesis	56/735	277/7206	4.17013357286e-07
ko04621	NOD-like receptor signaling pathway	1/735	157/7206	1.45366890804e-06
ko04270	Vascular smooth muscle contraction	1/735	154/7206	2.2546333349e-06
ko03022	Basal transcription factors	16/735	44/7206	3.13131755575e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/735	182/7206	8.93843781877e-06
ko04724	Glutamatergic synapse	2/735	152/7206	1.84508518931e-05
ko04723	Retrograde endocannabinoid signaling	3/735	175/7206	1.95190099968e-05
ko04514	Cell adhesion molecules (CAMs)	1/735	130/7206	2.45304376746e-05
ko04261	Adrenergic signaling in cardiomyocytes	5/735	205/7206	3.04832576285e-05
ko03450	Non-homologous end-joining	8/735	15/7206	3.77954468077e-05
ko00190	Oxidative phosphorylation	1/735	127/7206	3.79504051369e-05
ko04015	Rap1 signaling pathway	10/735	278/7206	4.51640729906e-05
ko04510	Focal adhesion	8/735	240/7206	8.01621386632e-05
ko04713	Circadian entrainment	2/735	136/7206	8.56487820496e-05
ko04921	Oxytocin signaling pathway	6/735	209/7206	0.000100685677443
ko05414	Dilated cardiomyopathy	1/735	112/7206	0.000116569434001
ko04218	Cellular senescence	35/735	177/7206	0.000120420140257
ko05152	Tuberculosis	5/735	187/7206	0.000120858848568
ko05012	Parkinson's disease	3/735	155/7206	0.000124139565647
ko04151	PI3K-Akt signaling pathway	19/735	390/7206	0.00013946735724
ko04014	Ras signaling pathway	11/735	279/7206	0.000160672910402
ko04810	Regulation of actin cytoskeleton	10/735	264/7206	0.000161548475165
ko04142	Lysosome	3/735	151/7206	0.000178953694857
ko05166	HTLV-I infection	50/735	292/7206	0.000224411750722
ko04725	Cholinergic synapse	4/735	160/7206	0.000297424424446
ko05410	Hypertrophic cardiomyopathy (HCM)	1/735	100/7206	0.000382096320952
ko04668	TNF signaling pathway	2/735	120/7206	0.000389340131315
ko04750	Inflammatory mediator regulation of TRP channels	2/735	122/7206	0.000395457484212
ko04010	MAPK signaling pathway	15/735	321/7206	0.000431123352336
ko04931	Insulin resistance	3/735	137/7206	0.000507260874668
ko04728	Dopaminergic synapse	6/735	185/7206	0.000510694348605
ko04062	Chemokine signaling pathway	7/735	201/7206	0.000534121143818
ko04974	Protein digestion and absorption	1/735	96/7206	0.000566527256794
ko04971	Gastric acid secretion	1/735	98/7206	0.000573979730936
ko04380	Osteoclast differentiation	3/735	134/7206	0.000739301711886
ko04070	Phosphatidylinositol signaling system	2/735	112/7206	0.000822549429323
ko04120	Ubiquitin mediated proteolysis	27/735	138/7206	0.00087420800329
ko04611	Platelet activation	5/735	163/7206	0.000929059818037
ko04915	Estrogen signaling pathway	3/735	131/7206	0.00108644100848
ko04727	GABAergic synapse	2/735	110/7206	0.00121014548454
ko05032	Morphine addiction	2/735	110/7206	0.00121014548454
ko04146	Peroxisome	1/735	89/7206	0.00123844282131
ko04972	Pancreatic secretion	2/735	111/7206	0.00124058250355
ko05031	Amphetamine addiction	1/735	91/7206	0.00128570500887
ko04115	p53 signaling pathway	17/735	74/7206	0.00133563992986
ko05205	Proteoglycans in cancer	13/735	271/7206	0.00145265624241
ko05145	Toxoplasmosis	3/735	126/7206	0.001507537819
ko00230	Purine metabolism	34/735	194/7206	0.00156677126398
ko03020	RNA polymerase	9/735	29/7206	0.0017386294373
ko04659	Th17 cell differentiation	2/735	106/7206	0.00175119573527
ko04924	Renin secretion	1/735	86/7206	0.00184868147243
ko04066	HIF-1 signaling pathway	3/735	123/7206	0.00220553778172
ko04726	Serotonergic synapse	4/735	137/7206	0.00238862972924
ko04620	Toll-like receptor signaling pathway	2/735	100/7206	0.0024925262871
ko04114	Oocyte meiosis	26/735	139/7206	0.00252308581428
ko04072	Phospholipase D signaling pathway	8/735	197/7206	0.00256297109964
ko05142	Chagas disease (American trypanosomiasis)	4/735	130/7206	0.00327206339001
ko04630	Jak-STAT signaling pathway	4/735	132/7206	0.00329398942402
ko04923	Regulation of lipolysis in adipocytes	1/735	77/7206	0.00397419176734
ko04721	Synaptic vesicle cycle	1/735	80/7206	0.0042477275897
ko04922	Glucagon signaling pathway	4/735	128/7206	0.00459963407517
ko04914	Progesterone-mediated oocyte maturation	20/735	104/7206	0.00481760028371
ko04530	Tight junction	11/735	228/7206	0.00507780872814
ko05030	Cocaine addiction	1/735	73/7206	0.00584683038098
ko05140	Leishmaniasis	1/735	75/7206	0.00602527107941
ko04912	GnRH signaling pathway	4/735	122/7206	0.00633870410337
ko05202	Transcriptional misregulation in cancer	31/735	188/7206	0.00676083462678
ko00562	Inositol phosphate metabolism	2/735	89/7206	0.00743591799719
ko04360	Axon guidance	12/735	233/7206	0.00787327452886
ko04371	Apelin signaling pathway	8/735	177/7206	0.00801836536089
ko04925	Aldosterone synthesis and secretion	3/735	105/7206	0.00844445916951
ko04670	Leukocyte transendothelial migration	6/735	151/7206	0.00902487252301
ko05418	Fluid shear stress and atherosclerosis	8/735	173/7206	0.0106476048173
ko04152	AMPK signaling pathway	7/735	161/7206	0.0115261072797
ko00670	One carbon pool by folate	6/735	20/7206	0.0122325010697
ko04138	Autophagy - yeast	2/735	81/7206	0.0152113089332
ko04658	Th1 and Th2 cell differentiation	3/735	96/7206	0.0164329124384
ko04660	T cell receptor signaling pathway	5/735	124/7206	0.016478458524
ko04650	Natural killer cell mediated cytotoxicity	3/735	97/7206	0.0166223342198
ko04742	Taste transduction	1/735	61/7206	0.0184460219423
ko04640	Hematopoietic cell lineage	1/735	64/7206	0.0195221524349
ko05200	Pathways in cancer	35/735	492/7206	0.0202678004513
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/735	135/7206	0.021239917417
ko04512	ECM-receptor interaction	2/735	79/7206	0.0224519371858
ko05120	Epithelial cell signaling in Helicobacter pylori infection	3/735	92/7206	0.0229307553107
ko04145	Phagosome	8/735	162/7206	0.0245937839569
ko04962	Vasopressin-regulated water reabsorption	1/735	58/7206	0.027163350659
ko05231	Choline metabolism in cancer	6/735	134/7206	0.0290938887421
ko04910	Insulin signaling pathway	9/735	172/7206	0.0292102296657
ko00010	Glycolysis / Gluconeogenesis	2/735	74/7206	0.0311947284757
ko05134	Legionellosis	2/735	74/7206	0.0311947284757
ko05133	Pertussis	3/735	87/7206	0.0317061057762
ko04662	B cell receptor signaling pathway	3/735	88/7206	0.0318830960607
ko05323	Rheumatoid arthritis	3/735	89/7206	0.0322827116024
ko01200	Carbon metabolism	6/735	128/7206	0.0378497493559
ko04540	Gap junction	6/735	128/7206	0.0378497493559
ko05016	Huntington's disease	13/735	215/7206	0.0392536971465
ko05160	Hepatitis C	8/735	153/7206	0.0416658616083
ko04720	Long-term potentiation	4/735	99/7206	0.0429661080045
ko00564	Glycerophospholipid metabolism	4/735	99/7206	0.0429661080045
ko04918	Thyroid hormone synthesis	3/735	86/7206	0.0455884849135
ko05168	Herpes simplex infection	27/735	182/7206	0.045985585481
ko04140	Autophagy - animal	9/735	164/7206	0.0488506164505
ko04666	Fc gamma R-mediated phagocytosis	6/735	122/7206	0.0497405959381