ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	60/491	152/7206	1.32645338174e-31
ko04080	Neuroactive ligand-receptor interaction	101/491	423/7206	2.05387057639e-31
ko05033	Nicotine addiction	33/491	56/7206	8.26149417869e-25
ko04713	Circadian entrainment	43/491	136/7206	1.68625562812e-18
ko04723	Retrograde endocannabinoid signaling	48/491	175/7206	1.10589296293e-17
ko04728	Dopaminergic synapse	49/491	185/7206	2.41636487782e-17
ko05032	Morphine addiction	37/491	110/7206	4.55948580912e-17
ko04727	GABAergic synapse	36/491	110/7206	3.34961654666e-16
ko04024	cAMP signaling pathway	58/491	279/7206	4.42115030721e-15
ko04721	Synaptic vesicle cycle	28/491	80/7206	1.06364875867e-13
ko04725	Cholinergic synapse	40/491	160/7206	1.94437914244e-13
ko04921	Oxytocin signaling pathway	45/491	209/7206	1.7830672183e-12
ko05031	Amphetamine addiction	27/491	91/7206	2.54700871421e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	24/491	74/7206	4.10531612852e-11
ko04911	Insulin secretion	29/491	117/7206	5.61687958174e-10
ko04720	Long-term potentiation	26/491	99/7206	1.16229613995e-09
ko05030	Cocaine addiction	22/491	73/7206	1.32442547358e-09
ko04742	Taste transduction	20/491	61/7206	1.4350572566e-09
ko04261	Adrenergic signaling in cardiomyocytes	39/491	205/7206	2.72354585345e-09
ko04020	Calcium signaling pathway	45/491	265/7206	6.79540089039e-09
ko04010	MAPK signaling pathway	50/491	321/7206	2.08321622647e-08
ko04726	Serotonergic synapse	29/491	137/7206	2.7330320734e-08
ko04730	Long-term depression	18/491	78/7206	3.36897807483e-06
ko04970	Salivary secretion	20/491	95/7206	4.4296370408e-06
ko04972	Pancreatic secretion	21/491	111/7206	1.49670945904e-05
ko04514	Cell adhesion molecules (CAMs)	23/491	130/7206	1.86607247869e-05
ko04060	Cytokine-cytokine receptor interaction	1/491	191/7206	3.02422272429e-05
ko04260	Cardiac muscle contraction	18/491	98/7206	9.08655922516e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/491	79/7206	0.000236887124152
ko04072	Phospholipase D signaling pathway	28/491	197/7206	0.00024244857552
ko04915	Estrogen signaling pathway	21/491	131/7206	0.000275244753561
ko04971	Gastric acid secretion	17/491	98/7206	0.000290789694344
ko04022	cGMP-PKG signaling pathway	28/491	216/7206	0.00085506902233
ko05164	Influenza A	2/491	167/7206	0.000972024540874
ko04120	Ubiquitin mediated proteolysis	1/491	138/7206	0.000994361168232
ko04540	Gap junction	19/491	128/7206	0.00110398437836
ko05414	Dilated cardiomyopathy	17/491	112/7206	0.00175361606209
ko04924	Renin secretion	14/491	86/7206	0.00185018049526
ko05203	Viral carcinogenesis	7/491	277/7206	0.00213667544756
ko04925	Aldosterone synthesis and secretion	16/491	105/7206	0.00241904020928
ko05162	Measles	1/491	120/7206	0.00312257577715
ko05034	Alcoholism	28/491	238/7206	0.00381006909335
ko04750	Inflammatory mediator regulation of TRP channels	17/491	122/7206	0.00527877009085
ko00240	Pyrimidine metabolism	1/491	110/7206	0.00667492297938
ko04141	Protein processing in endoplasmic reticulum	4/491	184/7206	0.00711538653214
ko05410	Hypertrophic cardiomyopathy (HCM)	14/491	100/7206	0.00833434251912
ko04350	TGF-beta signaling pathway	1/491	103/7206	0.0096707528646
ko04930	Type II diabetes mellitus	9/491	54/7206	0.00997057109333
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/491	14/7206	0.0123060977548
ko04745	Phototransduction - fly	7/491	38/7206	0.0129890759834
ko05322	Systemic lupus erythematosus	3/491	151/7206	0.0131619436678
ko05010	Alzheimer's disease	23/491	202/7206	0.0149401560061
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/491	59/7206	0.0174483214351
ko04550	Signaling pathways regulating pluripotency of stem cells	4/491	165/7206	0.0183481177174
ko05205	Proteoglycans in cancer	9/491	271/7206	0.0187083567656
ko04740	Olfactory transduction	11/491	80/7206	0.0224747809854
ko04360	Axon guidance	25/491	233/7206	0.0234851275151
ko05168	Herpes simplex infection	5/491	182/7206	0.024351843398
ko04150	mTOR signaling pathway	5/491	184/7206	0.0247024271559
ko04510	Focal adhesion	8/491	240/7206	0.0262298448547
ko04626	Plant-pathogen interaction	4/491	18/7206	0.030308986598
ko04146	Peroxisome	1/491	89/7206	0.0306538876313
ko05215	Prostate cancer	2/491	111/7206	0.0340428846856
ko04630	Jak-STAT signaling pathway	3/491	132/7206	0.0346438016088
ko04621	NOD-like receptor signaling pathway	4/491	157/7206	0.0350649884599
ko05110	Vibrio cholerae infection	9/491	63/7206	0.037369019428
ko04014	Ras signaling pathway	28/491	279/7206	0.0382703900863
ko04114	Oocyte meiosis	16/491	139/7206	0.0387665969372
ko03008	Ribosome biogenesis in eukaryotes	1/491	79/7206	0.0426099598615
ko00512	Mucin type O-glycan biosynthesis	5/491	29/7206	0.0438976181296
ko05169	Epstein-Barr virus infection	7/491	206/7206	0.0486060741909