ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	71/735	152/7206	1.83944863745e-31
ko05033	Nicotine addiction	42/735	56/7206	1.13319442248e-30
ko04080	Neuroactive ligand-receptor interaction	117/735	423/7206	7.47234372556e-26
ko05032	Morphine addiction	54/735	110/7206	1.88527475349e-25
ko04727	GABAergic synapse	53/735	110/7206	1.68775853688e-24
ko04723	Retrograde endocannabinoid signaling	63/735	175/7206	1.48664241934e-20
ko04728	Dopaminergic synapse	65/735	185/7206	1.59569191288e-20
ko04713	Circadian entrainment	52/735	136/7206	1.81072818764e-18
ko04721	Synaptic vesicle cycle	38/735	80/7206	1.30873952706e-17
ko04744	Phototransduction	25/735	36/7206	2.26583997548e-17
ko04725	Cholinergic synapse	53/735	160/7206	1.16947749462e-15
ko04024	cAMP signaling pathway	70/735	279/7206	3.08064955192e-13
ko04020	Calcium signaling pathway	66/735	265/7206	2.12262960647e-12
ko04742	Taste transduction	26/735	61/7206	4.13266370833e-11
ko04726	Serotonergic synapse	41/735	137/7206	8.56382950372e-11
ko04911	Insulin secretion	37/735	117/7206	1.24586536457e-10
ko05030	Cocaine addiction	26/735	73/7206	4.39202774546e-09
ko05031	Amphetamine addiction	29/735	91/7206	1.06364067427e-08
ko04921	Oxytocin signaling pathway	48/735	209/7206	4.0832582882e-08
ko04261	Adrenergic signaling in cardiomyocytes	47/735	205/7206	6.03319114063e-08
ko04720	Long-term potentiation	29/735	99/7206	8.6797462893e-08
ko04010	MAPK signaling pathway	60/735	321/7206	2.7152068262e-06
ko05203	Viral carcinogenesis	8/735	277/7206	3.97470773429e-06
ko03040	Spliceosome	1/735	145/7206	4.8393864891e-06
ko04060	Cytokine-cytokine receptor interaction	4/735	191/7206	1.69939764235e-05
ko04970	Salivary secretion	24/735	95/7206	1.9002615953e-05
ko04514	Cell adhesion molecules (CAMs)	29/735	130/7206	4.66447596295e-05
ko04022	cGMP-PKG signaling pathway	41/735	216/7206	8.05624966907e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/735	74/7206	0.000109622997893
ko04925	Aldosterone synthesis and secretion	24/735	105/7206	0.000119777327239
ko05164	Influenza A	4/735	167/7206	0.000146694290062
ko05168	Herpes simplex infection	5/735	182/7206	0.00017081330727
ko03013	RNA transport	4/735	166/7206	0.000216378081623
ko04730	Long-term depression	19/735	78/7206	0.000232034896398
ko04072	Phospholipase D signaling pathway	37/735	197/7206	0.000277319362526
ko05205	Proteoglycans in cancer	11/735	271/7206	0.00029554238226
ko04260	Cardiac muscle contraction	22/735	98/7206	0.000297660553807
ko04972	Pancreatic secretion	24/735	111/7206	0.000350235263231
ko05169	Epstein-Barr virus infection	7/735	206/7206	0.000390764625009
ko04120	Ubiquitin mediated proteolysis	3/735	138/7206	0.000516213215827
ko05322	Systemic lupus erythematosus	4/735	151/7206	0.000595565104268
ko04966	Collecting duct acid secretion	9/735	26/7206	0.00071769978958
ko04740	Olfactory transduction	18/735	80/7206	0.0011072964551
ko04110	Cell cycle	4/735	145/7206	0.00120832324057
ko04964	Proximal tubule bicarbonate reclamation	9/735	29/7206	0.0017386294373
ko04915	Estrogen signaling pathway	25/735	131/7206	0.00188396233517
ko05162	Measles	3/735	120/7206	0.00209041267687
ko04971	Gastric acid secretion	20/735	98/7206	0.00210402883211
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/735	79/7206	0.00234041310794
ko04141	Protein processing in endoplasmic reticulum	8/735	184/7206	0.00613907264576
ko04924	Renin secretion	17/735	86/7206	0.00641539738575
ko04070	Phosphatidylinositol signaling system	21/735	112/7206	0.00649221464914
ko04540	Gap junction	23/735	128/7206	0.00713900657644
ko04350	TGF-beta signaling pathway	3/735	103/7206	0.00834164180895
ko05034	Alcoholism	37/735	238/7206	0.00857812097462
ko04750	Inflammatory mediator regulation of TRP channels	22/735	122/7206	0.0092636670716
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/735	14/7206	0.00995238457083
ko04930	Type II diabetes mellitus	12/735	54/7206	0.010018723821
ko05110	Vibrio cholerae infection	13/735	63/7206	0.0109689787691
ko05414	Dilated cardiomyopathy	20/735	112/7206	0.0111583601068
ko04745	Phototransduction - fly	9/735	38/7206	0.0123010334938
ko04621	NOD-like receptor signaling pathway	7/735	157/7206	0.0154075265341
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/735	59/7206	0.016144430783
ko04064	NF-kappa B signaling pathway	3/735	96/7206	0.0164329124384
ko04371	Apelin signaling pathway	28/735	177/7206	0.0165318951999
ko05215	Prostate cancer	4/735	111/7206	0.0167838789536
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/735	182/7206	0.0175127135843
ko04071	Sphingolipid signaling pathway	26/735	162/7206	0.0175779969528
ko04140	Autophagy - animal	8/735	164/7206	0.0185565630906
ko04640	Hematopoietic cell lineage	1/735	64/7206	0.0195221524349
ko04610	Complement and coagulation cascades	2/735	79/7206	0.0224519371858
ko04360	Axon guidance	34/735	233/7206	0.0278226730234
ko04630	Jak-STAT signaling pathway	6/735	132/7206	0.0284522401388
ko05161	Hepatitis B	9/735	173/7206	0.0294784052497
ko05410	Hypertrophic cardiomyopathy (HCM)	17/735	100/7206	0.0300023532519
ko00310	Lysine degradation	2/735	73/7206	0.0307705153681
ko05140	Leishmaniasis	2/735	75/7206	0.0318801923411
ko04146	Peroxisome	3/735	89/7206	0.0322827116024
ko05166	HTLV-I infection	19/735	292/7206	0.0374009612602
ko04510	Focal adhesion	15/735	240/7206	0.03893512124
ko04976	Bile secretion	14/735	80/7206	0.0392689844869
ko00480	Glutathione metabolism	1/735	55/7206	0.0403340771197
ko04014	Ras signaling pathway	39/735	279/7206	0.0427777872933
ko03320	PPAR signaling pathway	2/735	69/7206	0.0435527934088
ko05131	Shigellosis	3/735	82/7206	0.0438797939837
ko04137	Mitophagy - animal	3/735	82/7206	0.0438797939837
ko03018	RNA degradation	3/735	84/7206	0.0441575598214
ko05220	Chronic myeloid leukemia	3/735	85/7206	0.0447293169808