ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 9/387 20/7206 3.35704697261e-07 ko04610 Complement and coagulation cascades 15/387 79/7206 1.55419601118e-05 ko05323 Rheumatoid arthritis 16/387 89/7206 1.67387371092e-05 ko04640 Hematopoietic cell lineage 13/387 64/7206 2.71264545432e-05 ko04060 Cytokine-cytokine receptor interaction 25/387 191/7206 2.83720225658e-05 ko00190 Oxidative phosphorylation 19/387 127/7206 4.18179981946e-05 ko04966 Collecting duct acid secretion 8/387 26/7206 4.27493058277e-05 ko00010 Glycolysis / Gluconeogenesis 13/387 74/7206 0.000132435744639 ko04630 Jak-STAT signaling pathway 18/387 132/7206 0.000223774888259 ko04380 Osteoclast differentiation 18/387 134/7206 0.000270792888878 ko04145 Phagosome 20/387 162/7206 0.000512757040924 ko05150 Staphylococcus aureus infection 8/387 36/7206 0.000515831574545 ko05144 Malaria 9/387 45/7206 0.000534333842444 ko04650 Natural killer cell mediated cytotoxicity 14/387 97/7206 0.00061825504361 ko04611 Platelet activation 19/387 163/7206 0.00122690056668 ko05224 Breast cancer 1/387 174/7206 0.00165844066235 ko04064 NF-kappa B signaling pathway 13/387 96/7206 0.00174772004169 ko00680 Methane metabolism 7/387 34/7206 0.00185845714996 ko04550 Signaling pathways regulating pluripotency of stem cells 1/387 165/7206 0.00234484681879 ko03013 RNA transport 1/387 166/7206 0.0023892075585 ko04146 Peroxisome 12/387 89/7206 0.00269561256932 ko00592 alpha-Linolenic acid metabolism 5/387 19/7206 0.00270592688908 ko05120 Epithelial cell signaling in Helicobacter pylori infection 12/387 92/7206 0.00356497177842 ko05340 Primary immunodeficiency 6/387 30/7206 0.004562974824 ko00380 Tryptophan metabolism 8/387 50/7206 0.00474356443467 ko00590 Arachidonic acid metabolism 8/387 52/7206 0.00605659477253 ko05110 Vibrio cholerae infection 9/387 63/7206 0.00608309792628 ko05152 Tuberculosis 19/387 187/7206 0.00739655326976 ko05310 Asthma 4/387 17/7206 0.011156162461 ko04137 Mitophagy - animal 10/387 82/7206 0.0119444730468 ko05200 Pathways in cancer 15/387 492/7206 0.0166689701049 ko05140 Leishmaniasis 9/387 75/7206 0.01838663274 ko05034 Alcoholism 5/387 238/7206 0.0185266993853 ko04666 Fc gamma R-mediated phagocytosis 13/387 122/7206 0.0225552205355 ko00051 Fructose and mannose metabolism 6/387 42/7206 0.0234925707755 ko01230 Biosynthesis of amino acids 10/387 85/7206 0.0240744511453 ko04110 Cell cycle 2/387 145/7206 0.0244593801182 ko04142 Lysosome 15/387 151/7206 0.0257854503451 ko05206 MicroRNAs in cancer 3/387 177/7206 0.0261966110899 ko01200 Carbon metabolism 13/387 128/7206 0.0262756189901 ko00030 Pentose phosphate pathway 5/387 32/7206 0.0264561662201 ko05203 Viral carcinogenesis 7/387 277/7206 0.0290071135234 ko05321 Inflammatory bowel disease (IBD) 7/387 56/7206 0.029215478056 ko04022 cGMP-PKG signaling pathway 19/387 216/7206 0.0307835705235 ko05215 Prostate cancer 1/387 111/7206 0.0309514566632 ko00620 Pyruvate metabolism 6/387 46/7206 0.035102766172 ko00362 Benzoate degradation 2/387 6/7206 0.0373659389082 ko04721 Synaptic vesicle cycle 9/387 80/7206 0.0386741564615 ko04660 T cell receptor signaling pathway 12/387 124/7206 0.0420118799778 ko05204 Chemical carcinogenesis 6/387 48/7206 0.0420843255416 ko04914 Progesterone-mediated oocyte maturation 1/387 104/7206 0.0447814017294 ko04932 Non-alcoholic fatty liver disease (NAFLD) 16/387 182/7206 0.0449846767022 ko04270 Vascular smooth muscle contraction 14/387 154/7206 0.0459258090324 ko01521 EGFR tyrosine kinase inhibitor resistance 1/387 106/7206 0.0459340832299 ko00982 Drug metabolism - cytochrome P450 5/387 37/7206 0.0461091874954 ko04139 Mitophagy - yeast 5/387 37/7206 0.0461091874954