ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	145/793	423/7206	3.17321281423e-40
ko05033	Nicotine addiction	48/793	56/7206	1.62983433531e-38
ko04724	Glutamatergic synapse	80/793	152/7206	8.58185192535e-38
ko05032	Morphine addiction	61/793	110/7206	1.15455799831e-30
ko04727	GABAergic synapse	59/793	110/7206	1.25705862566e-28
ko04723	Retrograde endocannabinoid signaling	71/793	175/7206	1.07161521993e-24
ko04728	Dopaminergic synapse	73/793	185/7206	1.74480789201e-24
ko04713	Circadian entrainment	59/793	136/7206	1.90623559479e-22
ko04725	Cholinergic synapse	59/793	160/7206	2.86941412609e-18
ko04721	Synaptic vesicle cycle	39/793	80/7206	2.21328569265e-17
ko04744	Phototransduction	25/793	36/7206	1.41904402365e-16
ko04024	cAMP signaling pathway	77/793	279/7206	3.6160350808e-15
ko04726	Serotonergic synapse	48/793	137/7206	4.4627975492e-14
ko04020	Calcium signaling pathway	72/793	265/7206	9.34202431758e-14
ko04911	Insulin secretion	43/793	117/7206	1.44043572126e-13
ko04742	Taste transduction	29/793	61/7206	6.83870290128e-13
ko04921	Oxytocin signaling pathway	60/793	209/7206	7.44891290158e-13
ko04720	Long-term potentiation	36/793	99/7206	2.07615322692e-11
ko05031	Amphetamine addiction	34/793	91/7206	3.17125228765e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/793	205/7206	4.26780256548e-10
ko05030	Cocaine addiction	27/793	73/7206	4.51571593683e-09
ko05203	Viral carcinogenesis	6/793	277/7206	3.69680898696e-08
ko04970	Salivary secretion	30/793	95/7206	4.38448962412e-08
ko04010	MAPK signaling pathway	66/793	321/7206	3.4128403693e-07
ko04925	Aldosterone synthesis and secretion	30/793	105/7206	5.16119398787e-07
ko04060	Cytokine-cytokine receptor interaction	3/793	191/7206	8.40605959859e-07
ko03040	Spliceosome	1/793	145/7206	1.31151490892e-06
ko04971	Gastric acid secretion	27/793	98/7206	4.11899072576e-06
ko04972	Pancreatic secretion	29/793	111/7206	7.97606969727e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	22/793	74/7206	8.41707065269e-06
ko04740	Olfactory transduction	23/793	80/7206	9.79802367566e-06
ko04022	cGMP-PKG signaling pathway	45/793	216/7206	1.99452134677e-05
ko04730	Long-term depression	22/793	78/7206	2.12736791607e-05
ko04072	Phospholipase D signaling pathway	42/793	197/7206	2.28021565419e-05
ko05169	Epstein-Barr virus infection	6/793	206/7206	2.31033165433e-05
ko05164	Influenza A	4/793	167/7206	4.73594526385e-05
ko04260	Cardiac muscle contraction	25/793	98/7206	4.93975615869e-05
ko05168	Herpes simplex infection	5/793	182/7206	5.74414370323e-05
ko04110	Cell cycle	3/793	145/7206	7.69718896725e-05
ko04745	Phototransduction - fly	13/793	38/7206	0.000123318271816
ko04070	Phosphatidylinositol signaling system	25/793	112/7206	0.000605398384459
ko04621	NOD-like receptor signaling pathway	5/793	157/7206	0.000661151044723
ko04120	Ubiquitin mediated proteolysis	4/793	138/7206	0.0008168878214
ko05322	Systemic lupus erythematosus	5/793	151/7206	0.000889371207931
ko05162	Measles	3/793	120/7206	0.000999640706761
ko04915	Estrogen signaling pathway	27/793	131/7206	0.00105157665004
ko04966	Collecting duct acid secretion	9/793	26/7206	0.0012486063028
ko04141	Protein processing in endoplasmic reticulum	8/793	184/7206	0.00178387236185
ko03013	RNA transport	7/793	166/7206	0.0024569913922
ko04924	Renin secretion	19/793	86/7206	0.0026192475235
ko04612	Antigen processing and presentation	1/793	77/7206	0.00268393818908
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/793	79/7206	0.00295076181859
ko04964	Proximal tubule bicarbonate reclamation	9/793	29/7206	0.00295640619754
ko04550	Signaling pathways regulating pluripotency of stem cells	7/793	165/7206	0.00342494305952
ko05110	Vibrio cholerae infection	15/793	63/7206	0.00345809848213
ko04014	Ras signaling pathway	46/793	279/7206	0.00448270340367
ko04630	Jak-STAT signaling pathway	5/793	132/7206	0.0045893702152
ko05205	Proteoglycans in cancer	16/793	271/7206	0.00531021602874
ko05414	Dilated cardiomyopathy	22/793	112/7206	0.00579116020049
ko05034	Alcoholism	40/793	238/7206	0.00588217166018
ko04140	Autophagy - animal	8/793	164/7206	0.00779809007436
ko04064	NF-kappa B signaling pathway	3/793	96/7206	0.00809177969687
ko04750	Inflammatory mediator regulation of TRP channels	23/793	122/7206	0.00829256650009
ko04640	Hematopoietic cell lineage	1/793	64/7206	0.00832601862805
ko04540	Gap junction	24/793	128/7206	0.00938552821883
ko05161	Hepatitis B	9/793	173/7206	0.00970663588738
ko05166	HTLV-I infection	19/793	292/7206	0.00981419261115
ko04514	Cell adhesion molecules (CAMs)	24/793	130/7206	0.0101803045222
ko03008	Ribosome biogenesis in eukaryotes	2/793	79/7206	0.0103603804354
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/793	59/7206	0.011435500395
ko04330	Notch signaling pathway	1/793	62/7206	0.0125433455642
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/793	14/7206	0.0136538440297
ko04371	Apelin signaling pathway	30/793	177/7206	0.0145685910394
ko05140	Leishmaniasis	2/793	75/7206	0.0147933387623
ko04510	Focal adhesion	15/793	240/7206	0.0153598613484
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/793	182/7206	0.0156433564568
ko04062	Chemokine signaling pathway	33/793	201/7206	0.0162486616173
ko05231	Choline metabolism in cancer	24/793	134/7206	0.0166913394466
ko04976	Bile secretion	16/793	80/7206	0.0175094579312
ko04214	Apoptosis - fly	2/793	72/7206	0.0213107521628
ko00310	Lysine degradation	2/793	73/7206	0.0217696310445
ko05215	Prostate cancer	5/793	111/7206	0.0218007896291
ko03018	RNA degradation	3/793	84/7206	0.022292491488
ko04670	Leukocyte transendothelial migration	8/793	151/7206	0.0243151669586
ko00562	Inositol phosphate metabolism	17/793	89/7206	0.0245052260569
ko04210	Apoptosis	11/793	180/7206	0.0299284399355
ko03320	PPAR signaling pathway	2/793	69/7206	0.0307728492576
ko05410	Hypertrophic cardiomyopathy (HCM)	18/793	100/7206	0.034566020964
ko00230	Purine metabolism	31/793	194/7206	0.0352196150068
ko04668	TNF signaling pathway	6/793	120/7206	0.03770561622
ko01524	Platinum drug resistance	3/793	76/7206	0.0430357484894
ko04973	Carbohydrate digestion and absorption	9/793	42/7206	0.0433861328888
ko05202	Transcriptional misregulation in cancer	12/793	188/7206	0.0436632081447
ko04930	Type II diabetes mellitus	11/793	54/7206	0.044660973078
ko05418	Fluid shear stress and atherosclerosis	11/793	173/7206	0.0485964634529
ko04015	Rap1 signaling pathway	41/793	278/7206	0.04993944959