ko pathway ratio_in_study ratio_in_pop p_value ko04713 Circadian entrainment 20/265 136/7206 9.60277705211e-08 ko04020 Calcium signaling pathway 28/265 265/7206 3.72544469997e-07 ko04724 Glutamatergic synapse 20/265 152/7206 6.1421184218e-07 ko04710 Circadian rhythm 10/265 43/7206 2.50180931885e-06 ko05031 Amphetamine addiction 14/265 91/7206 4.94696195762e-06 ko04080 Neuroactive ligand-receptor interaction 34/265 423/7206 1.28555640559e-05 ko04925 Aldosterone synthesis and secretion 14/265 105/7206 2.6779703685e-05 ko05032 Morphine addiction 14/265 110/7206 4.54786820021e-05 ko04720 Long-term potentiation 13/265 99/7206 6.11999991616e-05 ko00010 Glycolysis / Gluconeogenesis 11/265 74/7206 7.20908755583e-05 ko04725 Cholinergic synapse 17/265 160/7206 7.47110500712e-05 ko04921 Oxytocin signaling pathway 20/265 209/7206 7.81744962205e-05 ko04728 Dopaminergic synapse 18/265 185/7206 0.000144770525848 ko04024 cAMP signaling pathway 23/265 279/7206 0.000248010611258 ko04744 Phototransduction 7/265 36/7206 0.000280621830227 ko04745 Phototransduction - fly 7/265 38/7206 0.0003983948401 ko04740 Olfactory transduction 10/265 80/7206 0.000647420796049 ko04727 GABAergic synapse 12/265 110/7206 0.000675723282192 ko04930 Type II diabetes mellitus 8/265 54/7206 0.00072018297185 ko01200 Carbon metabolism 13/265 128/7206 0.000809681029956 ko04971 Gastric acid secretion 11/265 98/7206 0.000885686459957 ko05033 Nicotine addiction 8/265 56/7206 0.00092277790515 ko05014 Amyotrophic lateral sclerosis (ALS) 9/265 74/7206 0.00146201124776 ko04750 Inflammatory mediator regulation of TRP channels 12/265 122/7206 0.00168732302123 ko00710 Carbon fixation in photosynthetic organisms 5/265 27/7206 0.00268867532418 ko04626 Plant-pathogen interaction 4/265 18/7206 0.00363836128291 ko04911 Insulin secretion 11/265 117/7206 0.00370983514311 ko01230 Biosynthesis of amino acids 9/265 85/7206 0.00383516191071 ko04726 Serotonergic synapse 12/265 137/7206 0.00444084294631 ko00030 Pentose phosphate pathway 5/265 32/7206 0.00577470015675 ko00350 Tyrosine metabolism 5/265 33/7206 0.00660581476158 ko04922 Glucagon signaling pathway 11/265 128/7206 0.00730086328619 ko00680 Methane metabolism 5/265 34/7206 0.00751728518797 ko04070 Phosphatidylinositol signaling system 10/265 112/7206 0.00796501983805 ko04711 Circadian rhythm - fly 3/265 13/7206 0.0106937328385 ko04723 Retrograde endocannabinoid signaling 13/265 175/7206 0.013471175153 ko04371 Apelin signaling pathway 13/265 177/7206 0.0144968434132 ko04066 HIF-1 signaling pathway 10/265 123/7206 0.0148699895316 ko05168 Herpes simplex infection 1/265 182/7206 0.0151547860369 ko04960 Aldosterone-regulated sodium reabsorption 5/265 41/7206 0.0164462788417 ko00362 Benzoate degradation 2/265 6/7206 0.018323418293 ko04068 FoxO signaling pathway 12/265 167/7206 0.0216686475932 ko00360 Phenylalanine metabolism 3/265 17/7206 0.0228163325763 ko04970 Salivary secretion 8/265 95/7206 0.0231864030053 ko05214 Glioma 7/265 79/7206 0.0256077342501 ko04270 Vascular smooth muscle contraction 11/265 154/7206 0.0291365074479 ko04072 Phospholipase D signaling pathway 13/265 197/7206 0.0342651231226 ko04014 Ras signaling pathway 17/265 279/7206 0.0347137716238 ko04213 Longevity regulating pathway - multiple species 7/265 86/7206 0.038319658768 ko04211 Longevity regulating pathway 9/265 123/7206 0.0465274765731 ko04060 Cytokine-cytokine receptor interaction 2/265 191/7206 0.0492207496001