ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	113/631	423/7206	1.42202722738e-29
ko04724	Glutamatergic synapse	60/631	152/7206	1.59712799542e-25
ko05033	Nicotine addiction	36/631	56/7206	4.82587946658e-25
ko04727	GABAergic synapse	43/631	110/7206	2.27120132479e-18
ko05032	Morphine addiction	43/631	110/7206	2.27120132479e-18
ko04721	Synaptic vesicle cycle	35/631	80/7206	5.17781527606e-17
ko04728	Dopaminergic synapse	54/631	185/7206	3.58213639829e-16
ko04723	Retrograde endocannabinoid signaling	51/631	175/7206	2.67079660066e-15
ko04024	cAMP signaling pathway	67/631	279/7206	4.73081904776e-15
ko04713	Circadian entrainment	43/631	136/7206	1.84776223812e-14
ko04725	Cholinergic synapse	44/631	160/7206	2.19581508994e-12
ko04911	Insulin secretion	35/631	117/7206	3.16359642446e-11
ko04020	Calcium signaling pathway	54/631	265/7206	2.40452266054e-09
ko04261	Adrenergic signaling in cardiomyocytes	45/631	205/7206	4.08357727673e-09
ko04921	Oxytocin signaling pathway	45/631	209/7206	1.13214380347e-08
ko04726	Serotonergic synapse	34/631	137/7206	1.35745716056e-08
ko04742	Taste transduction	19/631	61/7206	5.41588390868e-07
ko04514	Cell adhesion molecules (CAMs)	30/631	130/7206	5.42264354337e-07
ko05030	Cocaine addiction	21/631	73/7206	6.1122699478e-07
ko04720	Long-term potentiation	25/631	99/7206	8.12200271705e-07
ko04970	Salivary secretion	24/631	95/7206	1.33712059014e-06
ko05031	Amphetamine addiction	23/631	91/7206	2.20128527917e-06
ko04010	MAPK signaling pathway	53/631	321/7206	4.20230870723e-06
ko04060	Cytokine-cytokine receptor interaction	2/631	191/7206	6.52025991904e-06
ko05203	Viral carcinogenesis	6/631	277/7206	6.7586951491e-06
ko04972	Pancreatic secretion	24/631	111/7206	2.39283490671e-05
ko03040	Spliceosome	1/631	145/7206	3.95949258519e-05
ko05164	Influenza A	2/631	167/7206	4.43761099192e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/631	74/7206	4.86023687977e-05
ko04072	Phospholipase D signaling pathway	35/631	197/7206	5.10252746832e-05
ko04022	cGMP-PKG signaling pathway	37/631	216/7206	6.72707598803e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/631	14/7206	7.58194222248e-05
ko04260	Cardiac muscle contraction	21/631	98/7206	8.78780101833e-05
ko04744	Phototransduction	11/631	36/7206	0.000166804187664
ko04966	Collecting duct acid secretion	9/631	26/7206	0.000228645647014
ko04730	Long-term depression	17/631	78/7206	0.000328547263603
ko04964	Proximal tubule bicarbonate reclamation	9/631	29/7206	0.000576987105688
ko04120	Ubiquitin mediated proteolysis	2/631	138/7206	0.000632723782044
ko04971	Gastric acid secretion	19/631	98/7206	0.000836683708303
ko05169	Epstein-Barr virus infection	6/631	206/7206	0.00104644337591
ko05322	Systemic lupus erythematosus	3/631	151/7206	0.00113075411647
ko04350	TGF-beta signaling pathway	1/631	103/7206	0.00133314428334
ko05205	Proteoglycans in cancer	10/631	271/7206	0.00137272164506
ko04141	Protein processing in endoplasmic reticulum	5/631	184/7206	0.00137845755123
ko04110	Cell cycle	3/631	145/7206	0.0015803598781
ko05168	Herpes simplex infection	5/631	182/7206	0.00195828877179
ko04925	Aldosterone synthesis and secretion	19/631	105/7206	0.00239462748559
ko05110	Vibrio cholerae infection	13/631	63/7206	0.00271723799492
ko05162	Measles	2/631	120/7206	0.00277586268085
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/631	79/7206	0.00382155791558
ko04630	Jak-STAT signaling pathway	3/631	132/7206	0.00452448845328
ko04745	Phototransduction - fly	9/631	38/7206	0.00460386442441
ko04550	Signaling pathways regulating pluripotency of stem cells	5/631	165/7206	0.00499126427374
ko03013	RNA transport	5/631	166/7206	0.00501665064536
ko05215	Prostate cancer	2/631	111/7206	0.00575105119684
ko04360	Axon guidance	33/631	233/7206	0.006236799609
ko04014	Ras signaling pathway	38/631	279/7206	0.00650480646651
ko04915	Estrogen signaling pathway	21/631	131/7206	0.00699521724533
ko05161	Hepatitis B	6/631	173/7206	0.00917969451323
ko04621	NOD-like receptor signaling pathway	5/631	157/7206	0.00942655544981
ko04070	Phosphatidylinositol signaling system	18/631	112/7206	0.0104347518772
ko05414	Dilated cardiomyopathy	18/631	112/7206	0.0104347518772
ko04924	Renin secretion	15/631	86/7206	0.0105166496456
ko00512	Mucin type O-glycan biosynthesis	7/631	29/7206	0.0108062087464
ko04612	Antigen processing and presentation	1/631	77/7206	0.0133674340103
ko03008	Ribosome biogenesis in eukaryotes	1/631	79/7206	0.0139591817669
ko05120	Epithelial cell signaling in Helicobacter pylori infection	15/631	92/7206	0.01525228307
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/631	59/7206	0.0166236588782
ko04140	Autophagy - animal	6/631	164/7206	0.0166421108766
ko04214	Apoptosis - fly	1/631	72/7206	0.0194022868521
ko00310	Lysine degradation	1/631	73/7206	0.0196775899888
ko04218	Cellular senescence	7/631	177/7206	0.0210138987959
ko04144	Endocytosis	42/631	342/7206	0.0236493512648
ko05166	HTLV-I infection	15/631	292/7206	0.0257617833048
ko05223	Non-small cell lung cancer	1/631	66/7206	0.0280626514885
ko03018	RNA degradation	2/631	84/7206	0.0318013942903
ko05410	Hypertrophic cardiomyopathy (HCM)	15/631	100/7206	0.0323705301432
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/631	182/7206	0.0329188904997
ko04071	Sphingolipid signaling pathway	22/631	162/7206	0.0343425443475
ko04510	Focal adhesion	12/631	240/7206	0.0359008763607
ko04068	FoxO signaling pathway	7/631	167/7206	0.0363250265637
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/631	15/7206	0.0364305983341
ko04540	Gap junction	18/631	128/7206	0.0393852881175
ko04640	Hematopoietic cell lineage	1/631	64/7206	0.0417583764327
ko04064	NF-kappa B signaling pathway	3/631	96/7206	0.0453222104102
ko05202	Transcriptional misregulation in cancer	9/631	188/7206	0.0496438685939