ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04744	Phototransduction	24/422	36/7206	9.17379353164e-22
ko04724	Glutamatergic synapse	46/422	152/7206	1.38563409958e-21
ko04727	GABAergic synapse	39/422	110/7206	3.1676766834e-21
ko05032	Morphine addiction	36/422	110/7206	2.40275181299e-18
ko05033	Nicotine addiction	25/422	56/7206	8.01540046526e-17
ko04713	Circadian entrainment	38/422	136/7206	1.1063010986e-16
ko04723	Retrograde endocannabinoid signaling	43/422	175/7206	1.80276169325e-16
ko04728	Dopaminergic synapse	44/422	185/7206	2.92561403355e-16
ko04080	Neuroactive ligand-receptor interaction	69/422	423/7206	1.32193224618e-15
ko04721	Synaptic vesicle cycle	26/422	80/7206	1.73955520154e-13
ko04725	Cholinergic synapse	36/422	160/7206	1.03789332023e-12
ko04740	Olfactory transduction	24/422	80/7206	1.06980095631e-11
ko04726	Serotonergic synapse	30/422	137/7206	1.78143787519e-10
ko04911	Insulin secretion	26/422	117/7206	2.17307232817e-09
ko04970	Salivary secretion	20/422	95/7206	4.13219406069e-07
ko04730	Long-term depression	17/422	78/7206	1.85272749322e-06
ko04024	cAMP signaling pathway	37/422	279/7206	2.6312775013e-06
ko05031	Amphetamine addiction	18/422	91/7206	4.06798166679e-06
ko04742	Taste transduction	14/422	61/7206	8.0047688046e-06
ko05203	Viral carcinogenesis	2/422	277/7206	1.14119421054e-05
ko04921	Oxytocin signaling pathway	29/422	209/7206	1.36610753165e-05
ko05030	Cocaine addiction	15/422	73/7206	1.60467705568e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/422	59/7206	2.69716040447e-05
ko04925	Aldosterone synthesis and secretion	18/422	105/7206	3.22119768747e-05
ko04745	Phototransduction - fly	10/422	38/7206	4.57242052486e-05
ko04971	Gastric acid secretion	16/422	98/7206	0.000160047334865
ko04720	Long-term potentiation	16/422	99/7206	0.000180857892731
ko04261	Adrenergic signaling in cardiomyocytes	26/422	205/7206	0.000195248065086
ko05168	Herpes simplex infection	1/422	182/7206	0.000328193888031
ko05034	Alcoholism	28/422	238/7206	0.000356005010026
ko04972	Pancreatic secretion	16/422	111/7206	0.000682908792459
ko05164	Influenza A	1/422	167/7206	0.000705550053946
ko05166	HTLV-I infection	5/422	292/7206	0.000802184657537
ko04964	Proximal tubule bicarbonate reclamation	7/422	29/7206	0.00113719989595
ko04540	Gap junction	17/422	128/7206	0.00162034358846
ko04020	Calcium signaling pathway	28/422	265/7206	0.0020012382648
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/422	182/7206	0.00207572167478
ko05205	Proteoglycans in cancer	5/422	271/7206	0.00213227183631
ko05322	Systemic lupus erythematosus	1/422	151/7206	0.00229342719512
ko03040	Spliceosome	1/422	145/7206	0.00339605137151
ko05169	Epstein-Barr virus infection	3/422	206/7206	0.00362784587525
ko04120	Ubiquitin mediated proteolysis	1/422	138/7206	0.00492749146657
ko04976	Bile secretion	11/422	80/7206	0.00657062267353
ko04810	Regulation of actin cytoskeleton	6/422	264/7206	0.00730709335444
ko04510	Focal adhesion	5/422	240/7206	0.00740947966058
ko04062	Chemokine signaling pathway	21/422	201/7206	0.00884542088923
ko04960	Aldosterone-regulated sodium reabsorption	7/422	41/7206	0.0089327639349
ko04371	Apelin signaling pathway	19/422	177/7206	0.00893977917097
ko04668	TNF signaling pathway	1/422	120/7206	0.00995273441444
ko04660	T cell receptor signaling pathway	1/422	124/7206	0.0103373963946
ko05014	Amyotrophic lateral sclerosis (ALS)	10/422	74/7206	0.0105470269104
ko04022	cGMP-PKG signaling pathway	22/422	216/7206	0.0112660179456
ko00230	Purine metabolism	20/422	194/7206	0.0122560248978
ko04218	Cellular senescence	3/422	177/7206	0.0136443765205
ko04924	Renin secretion	11/422	86/7206	0.0166122540764
ko04918	Thyroid hormone synthesis	11/422	86/7206	0.0166122540764
ko04110	Cell cycle	2/422	145/7206	0.0180090015722
ko04014	Ras signaling pathway	26/422	279/7206	0.0182683131083
ko04060	Cytokine-cytokine receptor interaction	4/422	191/7206	0.0187034447582
ko05215	Prostate cancer	1/422	111/7206	0.0219271803083
ko04514	Cell adhesion molecules (CAMs)	14/422	130/7206	0.0228296561393
ko04380	Osteoclast differentiation	2/422	134/7206	0.0243108613999
ko04141	Protein processing in endoplasmic reticulum	4/422	184/7206	0.0254409731277
ko04978	Mineral absorption	6/422	40/7206	0.027485835615
ko04260	Cardiac muscle contraction	11/422	98/7206	0.0301275000943
ko04750	Inflammatory mediator regulation of TRP channels	13/422	122/7206	0.0309554526584
ko04217	Necroptosis	4/422	178/7206	0.0345305386728
ko04210	Apoptosis	4/422	180/7206	0.0348456990377
ko05160	Hepatitis C	3/422	153/7206	0.0351872016309
ko04621	NOD-like receptor signaling pathway	3/422	157/7206	0.0364244009557
ko04010	MAPK signaling pathway	28/422	321/7206	0.0373762964899
ko05211	Renal cell carcinoma	1/422	96/7206	0.0447069165556
ko04658	Th1 and Th2 cell differentiation	1/422	96/7206	0.0447069165556
ko05161	Hepatitis B	4/422	173/7206	0.0470575752814