ko pathway ratio_in_study ratio_in_pop p_value ko04550 Signaling pathways regulating pluripotency of stem cells 38/403 165/7206 2.4086108838e-14 ko05217 Basal cell carcinoma 24/403 68/7206 6.8975786067e-14 ko04360 Axon guidance 40/403 233/7206 1.07368360308e-10 ko05200 Pathways in cancer 61/403 492/7206 2.50520317834e-09 ko04310 Wnt signaling pathway 31/403 181/7206 1.59469537236e-08 ko05224 Breast cancer 30/403 174/7206 2.34315650354e-08 ko04390 Hippo signaling pathway 31/403 188/7206 3.99960978886e-08 ko04340 Hedgehog signaling pathway 16/403 58/7206 6.22316358456e-08 ko04330 Notch signaling pathway 16/403 62/7206 1.72924551828e-07 ko04110 Cell cycle 25/403 145/7206 3.58509730554e-07 ko05202 Transcriptional misregulation in cancer 27/403 188/7206 4.95431288626e-06 ko04111 Cell cycle - yeast 17/403 90/7206 7.82064131096e-06 ko05206 MicroRNAs in cancer 25/403 177/7206 1.5013363909e-05 ko04080 Neuroactive ligand-receptor interaction 6/403 423/7206 1.54619552532e-05 ko04950 Maturity onset diabetes of the young 9/403 29/7206 1.79971448465e-05 ko04350 TGF-beta signaling pathway 16/403 103/7206 0.000170973658914 ko04919 Thyroid hormone signaling pathway 19/403 143/7206 0.000356459578468 ko04391 Hippo signaling pathway - fly 14/403 90/7206 0.000425749214755 ko05205 Proteoglycans in cancer 29/403 271/7206 0.000644524035145 ko04022 cGMP-PKG signaling pathway 2/403 216/7206 0.000731149499982 ko05166 HTLV-I infection 30/403 292/7206 0.00103292665451 ko04921 Oxytocin signaling pathway 2/403 209/7206 0.00105538311756 ko04020 Calcium signaling pathway 4/403 265/7206 0.00146560181037 ko05010 Alzheimer's disease 2/403 202/7206 0.00152066522157 ko04113 Meiosis - yeast 11/403 70/7206 0.00159000240714 ko00310 Lysine degradation 11/403 73/7206 0.00224941814077 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 6/403 26/7206 0.00260588239158 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/403 182/7206 0.0029894755453 ko04724 Glutamatergic synapse 1/403 152/7206 0.00343696057208 ko05222 Small cell lung cancer 12/403 89/7206 0.00375443908331 ko04723 Retrograde endocannabinoid signaling 2/403 175/7206 0.00426627863137 ko04341 Hedgehog signaling pathway - fly 7/403 38/7206 0.00453379964204 ko03410 Base excision repair 7/403 38/7206 0.00453379964204 ko05215 Prostate cancer 14/403 111/7206 0.00499644870698 ko04726 Serotonergic synapse 1/403 137/7206 0.00717638831325 ko04520 Adherens junction 13/403 103/7206 0.00720946506827 ko04916 Melanogenesis 16/403 142/7206 0.00809566571386 ko04725 Cholinergic synapse 2/403 160/7206 0.00863228408876 ko04611 Platelet activation 2/403 163/7206 0.00870939392344 ko01200 Carbon metabolism 1/403 128/7206 0.0101660131964 ko04270 Vascular smooth muscle contraction 2/403 154/7206 0.0122393980453 ko04013 MAPK signaling pathway - fly 13/403 115/7206 0.0128844835705 ko04062 Chemokine signaling pathway 4/403 201/7206 0.0188062543361 ko04972 Pancreatic secretion 1/403 111/7206 0.0210140339039 ko05032 Morphine addiction 1/403 110/7206 0.0210249300403 ko00230 Purine metabolism 4/403 194/7206 0.025605584503 ko04072 Phospholipase D signaling pathway 4/403 197/7206 0.026018983405 ko05218 Melanoma 10/403 85/7206 0.0268910107057 ko05220 Chronic myeloid leukemia 10/403 85/7206 0.0268910107057 ko04011 MAPK signaling pathway - yeast 7/403 53/7206 0.0270662043783 ko05034 Alcoholism 6/403 238/7206 0.0311426987633 ko04915 Estrogen signaling pathway 2/403 131/7206 0.0341522294764 ko04141 Protein processing in endoplasmic reticulum 4/403 184/7206 0.034628345799 ko03015 mRNA surveillance pathway 10/403 93/7206 0.0387795627227 ko04650 Natural killer cell mediated cytotoxicity 1/403 97/7206 0.0437443409525 ko04260 Cardiac muscle contraction 1/403 98/7206 0.0439216282531 ko04971 Gastric acid secretion 1/403 98/7206 0.0439216282531 ko04261 Adrenergic signaling in cardiomyocytes 5/403 205/7206 0.0441493875494 ko04217 Necroptosis 4/403 178/7206 0.0466840066187 ko05322 Systemic lupus erythematosus 3/403 151/7206 0.0482055109142 ko04150 mTOR signaling pathway 17/403 184/7206 0.0483633949071