ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04380	Osteoclast differentiation	41/489	134/7206	3.57277543478e-17
ko04060	Cytokine-cytokine receptor interaction	43/489	191/7206	1.00171756429e-12
ko04621	NOD-like receptor signaling pathway	37/489	157/7206	9.76340476207e-12
ko04064	NF-kappa B signaling pathway	28/489	96/7206	1.54890805819e-11
ko05164	Influenza A	34/489	167/7206	4.37863276113e-09
ko05162	Measles	28/489	120/7206	4.46041774389e-09
ko04658	Th1 and Th2 cell differentiation	24/489	96/7206	1.36588670287e-08
ko04217	Necroptosis	34/489	178/7206	2.40153143136e-08
ko04659	Th17 cell differentiation	25/489	106/7206	2.42398139608e-08
ko05168	Herpes simplex infection	34/489	182/7206	4.28083667599e-08
ko05140	Leishmaniasis	20/489	75/7206	7.01785784627e-08
ko05321	Inflammatory bowel disease (IBD)	16/489	56/7206	5.21585938079e-07
ko04620	Toll-like receptor signaling pathway	22/489	100/7206	6.20784943889e-07
ko05145	Toxoplasmosis	25/489	126/7206	8.54501830159e-07
ko04650	Natural killer cell mediated cytotoxicity	21/489	97/7206	1.48007179757e-06
ko05340	Primary immunodeficiency	11/489	30/7206	2.10139751521e-06
ko05150	Staphylococcus aureus infection	12/489	36/7206	2.32111696602e-06
ko00120	Primary bile acid biosynthesis	9/489	20/7206	2.42577437408e-06
ko04610	Complement and coagulation cascades	18/489	79/7206	3.86279693005e-06
ko04630	Jak-STAT signaling pathway	24/489	132/7206	7.072227497e-06
ko05167	Kaposi's sarcoma-associated herpesvirus infection	30/489	191/7206	1.26728112141e-05
ko05161	Hepatitis B	28/489	173/7206	1.7154165065e-05
ko04662	B cell receptor signaling pathway	18/489	88/7206	1.91351627992e-05
ko04660	T cell receptor signaling pathway	22/489	124/7206	2.53962721609e-05
ko04668	TNF signaling pathway	21/489	120/7206	4.78134909667e-05
ko04622	RIG-I-like receptor signaling pathway	14/489	62/7206	5.13215982991e-05
ko04623	Cytosolic DNA-sensing pathway	11/489	41/7206	6.12855722379e-05
ko04723	Retrograde endocannabinoid signaling	1/489	175/7206	9.83931301001e-05
ko05160	Hepatitis C	24/489	153/7206	0.000107052334237
ko04672	Intestinal immune network for IgA production	10/489	37/7206	0.000123920340535
ko05152	Tuberculosis	27/489	187/7206	0.000163842197605
ko00350	Tyrosine metabolism	9/489	33/7206	0.000251138312456
ko05142	Chagas disease (American trypanosomiasis)	21/489	130/7206	0.000256795656994
ko00950	Isoquinoline alkaloid biosynthesis	5/489	10/7206	0.000266940732648
ko05323	Rheumatoid arthritis	16/489	89/7206	0.000273275910543
ko05034	Alcoholism	4/489	238/7206	0.000353217069013
ko04728	Dopaminergic synapse	2/489	185/7206	0.000494942980287
ko00360	Phenylalanine metabolism	6/489	17/7206	0.000614664790278
ko05133	Pertussis	15/489	87/7206	0.000668869446623
ko03040	Spliceosome	1/489	145/7206	0.000678845137128
ko05144	Malaria	10/489	45/7206	0.000694172402555
ko04611	Platelet activation	23/489	163/7206	0.000720770165873
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/489	4/7206	0.00117994869168
ko04210	Apoptosis	24/489	180/7206	0.0013299553813
ko04666	Fc gamma R-mediated phagocytosis	18/489	122/7206	0.00154790919696
ko03010	Ribosome	1/489	129/7206	0.00216568070996
ko04062	Chemokine signaling pathway	25/489	201/7206	0.00264818404735
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	3/489	5/7206	0.00280111081957
ko04640	Hematopoietic cell lineage	11/489	64/7206	0.0034891464462
ko05169	Epstein-Barr virus infection	25/489	206/7206	0.00438508879589
ko05330	Allograft rejection	6/489	24/7206	0.00444955255534
ko04933	AGE-RAGE signaling pathway in diabetic complications	18/489	135/7206	0.00503758279329
ko04612	Antigen processing and presentation	12/489	77/7206	0.00533077540526
ko05016	Huntington's disease	5/489	215/7206	0.00537168710711
ko05332	Graft-versus-host disease	5/489	18/7206	0.0057616286391
ko05166	HTLV-I infection	32/489	292/7206	0.00607359118929
ko04727	GABAergic synapse	1/489	110/7206	0.00666329072571
ko04710	Circadian rhythm	8/489	43/7206	0.00745914754714
ko05146	Amoebiasis	14/489	99/7206	0.00754703836316
ko00590	Arachidonic acid metabolism	9/489	52/7206	0.00758185097971
ko04657	IL-17 signaling pathway	13/489	87/7206	0.00762096956414
ko04713	Circadian entrainment	2/489	136/7206	0.00859539821594
ko04310	Wnt signaling pathway	4/489	181/7206	0.00997945442724
ko05320	Autoimmune thyroid disease	6/489	29/7206	0.0117720968727
ko05131	Shigellosis	12/489	82/7206	0.01187946477
ko05134	Legionellosis	11/489	74/7206	0.0160137258172
ko04360	Axon guidance	7/489	233/7206	0.0164463349507
ko04390	Hippo signaling pathway	5/489	188/7206	0.0180478978441
ko04916	Melanogenesis	3/489	142/7206	0.0180551129559
ko04110	Cell cycle	3/489	145/7206	0.0182059753759
ko04072	Phospholipase D signaling pathway	22/489	197/7206	0.0202892589281
ko00330	Arginine and proline metabolism	9/489	61/7206	0.0208617486626
ko00565	Ether lipid metabolism	7/489	42/7206	0.0215399403403
ko05310	Asthma	4/489	17/7206	0.024544847044
ko04726	Serotonergic synapse	3/489	137/7206	0.024970021073
ko04137	Mitophagy - animal	11/489	82/7206	0.0249893895705
ko00643	Styrene degradation	2/489	4/7206	0.0251545064841
ko05212	Pancreatic cancer	11/489	83/7206	0.0266492891737
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/489	92/7206	0.0326315720511
ko04012	ErbB signaling pathway	2/489	109/7206	0.0333935535659
ko05032	Morphine addiction	2/489	110/7206	0.0335808668768
ko04724	Glutamatergic synapse	4/489	152/7206	0.0338923630105
ko00592	alpha-Linolenic acid metabolism	4/489	19/7206	0.0359169143568
ko04974	Protein digestion and absorption	12/489	96/7206	0.0374368984991
ko04664	Fc epsilon RI signaling pathway	10/489	77/7206	0.0386978102864
ko05132	Salmonella infection	12/489	98/7206	0.0406814117559
ko04740	Olfactory transduction	1/489	80/7206	0.0426907153989
ko04068	FoxO signaling pathway	18/489	167/7206	0.0430976214986