ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	30/418	56/7206	4.81812489256e-23
ko04080	Neuroactive ligand-receptor interaction	79/418	423/7206	7.46158832874e-22
ko04724	Glutamatergic synapse	39/418	152/7206	7.46235084789e-16
ko04727	GABAergic synapse	32/418	110/7206	6.89226216928e-15
ko05032	Morphine addiction	30/418	110/7206	3.29304938284e-13
ko04723	Retrograde endocannabinoid signaling	37/418	175/7206	2.77354063328e-12
ko04728	Dopaminergic synapse	38/418	185/7206	3.55462629234e-12
ko04713	Circadian entrainment	31/418	136/7206	2.28106509206e-11
ko04721	Synaptic vesicle cycle	23/418	80/7206	6.32201934046e-11
ko05030	Cocaine addiction	19/418	73/7206	1.85390977595e-08
ko04024	cAMP signaling pathway	41/418	279/7206	2.28090839288e-08
ko04725	Cholinergic synapse	29/418	160/7206	2.87287503154e-08
ko04010	MAPK signaling pathway	43/418	321/7206	2.22924577806e-07
ko04360	Axon guidance	34/418	233/7206	4.57156720397e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	17/418	74/7206	7.37200561802e-07
ko04921	Oxytocin signaling pathway	31/418	209/7206	1.04502493109e-06
ko04726	Serotonergic synapse	23/418	137/7206	3.21203691541e-06
ko04911	Insulin secretion	20/418	117/7206	1.06979259263e-05
ko05031	Amphetamine addiction	17/418	91/7206	1.47825094059e-05
ko04514	Cell adhesion molecules (CAMs)	21/418	130/7206	1.59507539952e-05
ko04261	Adrenergic signaling in cardiomyocytes	28/418	205/7206	2.15136723349e-05
ko04742	Taste transduction	13/418	61/7206	3.55678688618e-05
ko04970	Salivary secretion	16/418	95/7206	9.79698301e-05
ko04720	Long-term potentiation	16/418	99/7206	0.000162014088211
ko05203	Viral carcinogenesis	4/418	277/7206	0.000530670808207
ko04972	Pancreatic secretion	16/418	111/7206	0.000615649756193
ko04015	Rap1 signaling pathway	30/418	278/7206	0.000906344312508
ko04964	Proximal tubule bicarbonate reclamation	7/418	29/7206	0.00107515777506
ko05164	Influenza A	1/418	167/7206	0.00109310937931
ko04060	Cytokine-cytokine receptor interaction	2/418	191/7206	0.00145154504901
ko04260	Cardiac muscle contraction	14/418	98/7206	0.0014519043499
ko04971	Gastric acid secretion	14/418	98/7206	0.0014519043499
ko04020	Calcium signaling pathway	28/418	265/7206	0.00183243039804
ko05205	Proteoglycans in cancer	5/418	271/7206	0.00210370688112
ko05169	Epstein-Barr virus infection	3/418	206/7206	0.00354768916475
ko04120	Ubiquitin mediated proteolysis	1/418	138/7206	0.00483110435417
ko04730	Long-term depression	11/418	78/7206	0.00504481757904
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11/418	79/7206	0.0055646127774
ko03013	RNA transport	2/418	166/7206	0.00621464648562
ko01200	Carbon metabolism	1/418	128/7206	0.00686147319424
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/418	14/7206	0.00701217894593
ko04630	Jak-STAT signaling pathway	1/418	132/7206	0.00712229309813
ko04621	NOD-like receptor signaling pathway	2/418	157/7206	0.00865418762309
ko02024	Quorum sensing	4/418	15/7206	0.0091310922412
ko04925	Aldosterone synthesis and secretion	13/418	105/7206	0.00921296108027
ko05162	Measles	1/418	120/7206	0.0099702277939
ko04915	Estrogen signaling pathway	15/418	131/7206	0.0120211509054
ko04217	Necroptosis	3/418	178/7206	0.0135629131907
ko05414	Dilated cardiomyopathy	13/418	112/7206	0.0136940116245
ko04071	Sphingolipid signaling pathway	17/418	162/7206	0.0159776901924
ko04961	Endocrine and other factor-regulated calcium reabsorption	8/418	59/7206	0.0197063623595
ko04540	Gap junction	14/418	128/7206	0.0199718586317
ko00240	Pyrimidine metabolism	1/418	110/7206	0.0213042772223
ko04976	Bile secretion	10/418	80/7206	0.0248524676686
ko04140	Autophagy - animal	3/418	164/7206	0.0260273240792
ko04014	Ras signaling pathway	25/418	279/7206	0.0261371235156
ko04072	Phospholipase D signaling pathway	19/418	197/7206	0.0286841431946
ko00564	Glycerophospholipid metabolism	1/418	99/7206	0.0302211274016
ko04350	TGF-beta signaling pathway	1/418	103/7206	0.0307440802882
ko05168	Herpes simplex infection	4/418	182/7206	0.0349401934049
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/418	182/7206	0.0349401934049
ko04940	Type I diabetes mellitus	5/418	32/7206	0.0353507105028
ko04150	mTOR signaling pathway	4/418	184/7206	0.0355396534196
ko04141	Protein processing in endoplasmic reticulum	4/418	184/7206	0.0355396534196
ko05166	HTLV-I infection	9/418	292/7206	0.0404084402725
ko00430	Taurine and hypotaurine metabolism	3/418	14/7206	0.0437332016457
ko05161	Hepatitis B	4/418	173/7206	0.0467040217997
ko04218	Cellular senescence	4/418	177/7206	0.0480228498674
ko04110	Cell cycle	3/418	145/7206	0.0480316374627
ko04066	HIF-1 signaling pathway	2/418	123/7206	0.0484999445952
ko04510	Focal adhesion	7/418	240/7206	0.0491577514186
ko05322	Systemic lupus erythematosus	3/418	151/7206	0.0497212362532