ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	69/668	152/7206	2.81858581824e-32
ko05033	Nicotine addiction	41/668	56/7206	6.08882833175e-31
ko04080	Neuroactive ligand-receptor interaction	116/668	423/7206	3.83303218702e-29
ko04744	Phototransduction	27/668	36/7206	3.33414110265e-21
ko04727	GABAergic synapse	47/668	110/7206	7.13770771203e-21
ko04728	Dopaminergic synapse	61/668	185/7206	7.46206596351e-20
ko04713	Circadian entrainment	51/668	136/7206	1.56384644517e-19
ko04723	Retrograde endocannabinoid signaling	58/668	175/7206	4.82281321317e-19
ko05032	Morphine addiction	44/668	110/7206	2.8888236127e-18
ko04725	Cholinergic synapse	47/668	160/7206	2.14673109677e-13
ko04721	Synaptic vesicle cycle	31/668	80/7206	8.72565802893e-13
ko04740	Olfactory transduction	29/668	80/7206	3.35230651872e-11
ko04726	Serotonergic synapse	39/668	137/7206	7.33895018813e-11
ko04024	cAMP signaling pathway	61/668	279/7206	1.09055490348e-10
ko05030	Cocaine addiction	26/668	73/7206	5.55083380354e-10
ko05031	Amphetamine addiction	29/668	91/7206	1.15927204181e-09
ko04742	Taste transduction	23/668	61/7206	1.52267683812e-09
ko04911	Insulin secretion	33/668	117/7206	2.83988269422e-09
ko04720	Long-term potentiation	27/668	99/7206	1.70892158547e-07
ko04261	Adrenergic signaling in cardiomyocytes	42/668	205/7206	5.72917557652e-07
ko04921	Oxytocin signaling pathway	42/668	209/7206	1.21022459549e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/668	74/7206	1.99628745428e-06
ko04970	Salivary secretion	24/668	95/7206	3.68165764499e-06
ko04020	Calcium signaling pathway	47/668	265/7206	1.13037801313e-05
ko03040	Spliceosome	1/668	145/7206	1.71372242487e-05
ko05203	Viral carcinogenesis	8/668	277/7206	3.18132355144e-05
ko04120	Ubiquitin mediated proteolysis	1/668	138/7206	3.87357140613e-05
ko04730	Long-term depression	19/668	78/7206	6.48287970472e-05
ko05164	Influenza A	3/668	167/7206	0.00012524039021
ko04022	cGMP-PKG signaling pathway	37/668	216/7206	0.000192241473028
ko04745	Phototransduction - fly	11/668	38/7206	0.000466394256711
ko04060	Cytokine-cytokine receptor interaction	5/668	191/7206	0.000523336404018
ko05034	Alcoholism	38/668	238/7206	0.000854483964623
ko05162	Measles	2/668	120/7206	0.00125444712474
ko05205	Proteoglycans in cancer	11/668	271/7206	0.00128351901306
ko04010	MAPK signaling pathway	47/668	321/7206	0.001501405151
ko04925	Aldosterone synthesis and secretion	20/668	105/7206	0.0017605570148
ko04514	Cell adhesion molecules (CAMs)	23/668	130/7206	0.00204012706282
ko05322	Systemic lupus erythematosus	4/668	151/7206	0.00250445119807
ko05168	Herpes simplex infection	6/668	182/7206	0.00265465697435
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/668	182/7206	0.00265465697435
ko04260	Cardiac muscle contraction	18/668	98/7206	0.00425876294284
ko05169	Epstein-Barr virus infection	8/668	206/7206	0.00469478226325
ko04621	NOD-like receptor signaling pathway	5/668	157/7206	0.00493097653061
ko05161	Hepatitis B	6/668	173/7206	0.00493602910248
ko04072	Phospholipase D signaling pathway	30/668	197/7206	0.00582113214562
ko04014	Ras signaling pathway	40/668	279/7206	0.00582812394858
ko04150	mTOR signaling pathway	7/668	184/7206	0.00649340439099
ko04924	Renin secretion	16/668	86/7206	0.00723144702049
ko04972	Pancreatic secretion	19/668	111/7206	0.00758884533068
ko00564	Glycerophospholipid metabolism	2/668	99/7206	0.0078055635505
ko03013	RNA transport	6/668	166/7206	0.00928925371904
ko04610	Complement and coagulation cascades	1/668	79/7206	0.00939439631125
ko05166	HTLV-I infection	15/668	292/7206	0.0099071384924
ko05215	Prostate cancer	3/668	111/7206	0.0122260721487
ko04971	Gastric acid secretion	17/668	98/7206	0.0122885892099
ko04110	Cell cycle	5/668	145/7206	0.012841301315
ko04214	Apoptosis - fly	1/668	72/7206	0.0130362834013
ko04930	Type II diabetes mellitus	11/668	54/7206	0.0146018973204
ko04146	Peroxisome	2/668	89/7206	0.015663583952
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/668	79/7206	0.016910958865
ko04510	Focal adhesion	12/668	240/7206	0.0171690519943
ko04976	Bile secretion	14/668	80/7206	0.0180228894257
ko04062	Chemokine signaling pathway	29/668	201/7206	0.0181330584292
ko04141	Protein processing in endoplasmic reticulum	8/668	184/7206	0.01942727262
ko03018	RNA degradation	2/668	84/7206	0.0221807073407
ko04350	TGF-beta signaling pathway	3/668	103/7206	0.0240905151311
ko04330	Notch signaling pathway	1/668	62/7206	0.0276978657334
ko00561	Glycerolipid metabolism	1/668	63/7206	0.0277028129371
ko04978	Mineral absorption	8/668	40/7206	0.0279757807875
ko03008	Ribosome biogenesis in eukaryotes	2/668	79/7206	0.0313735353048
ko04064	NF-kappa B signaling pathway	3/668	96/7206	0.0325032283281
ko04371	Apelin signaling pathway	25/668	177/7206	0.0343569408795
ko04360	Axon guidance	31/668	233/7206	0.0379777278913
ko01212	Fatty acid metabolism	1/668	60/7206	0.0408953988841
ko05145	Toxoplasmosis	5/668	126/7206	0.0419620782362
ko05140	Leishmaniasis	2/668	75/7206	0.0442852765308
ko00240	Pyrimidine metabolism	4/668	110/7206	0.0444410868582
ko01524	Platinum drug resistance	2/668	76/7206	0.0445668325436
ko05130	Pathogenic Escherichia coli infection	2/668	77/7206	0.0451355165107
ko04964	Proximal tubule bicarbonate reclamation	6/668	29/7206	0.0465603116406
ko04915	Estrogen signaling pathway	19/668	131/7206	0.0465934779407
ko04217	Necroptosis	9/668	178/7206	0.0491893940672