ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 17/177 36/7206 1.14115347063e-18 ko04727 GABAergic synapse 22/177 110/7206 1.23166252022e-14 ko04724 Glutamatergic synapse 25/177 152/7206 2.03743334498e-14 ko05032 Morphine addiction 19/177 110/7206 1.3754981616e-11 ko05033 Nicotine addiction 14/177 56/7206 4.10930832346e-11 ko04723 Retrograde endocannabinoid signaling 22/177 175/7206 2.04821756514e-10 ko04713 Circadian entrainment 16/177 136/7206 1.78781013876e-07 ko04721 Synaptic vesicle cycle 12/177 80/7206 4.67674737003e-07 ko04728 Dopaminergic synapse 18/177 185/7206 5.40964889385e-07 ko04911 Insulin secretion 13/177 117/7206 5.09512552574e-06 ko04726 Serotonergic synapse 14/177 137/7206 5.91343057877e-06 ko05030 Cocaine addiction 10/177 73/7206 1.00964790684e-05 ko05034 Alcoholism 17/177 238/7206 6.98824759627e-05 ko04514 Cell adhesion molecules (CAMs) 12/177 130/7206 7.69059898283e-05 ko04080 Neuroactive ligand-receptor interaction 24/177 423/7206 0.0001145645759 ko04024 cAMP signaling pathway 18/177 279/7206 0.000157754056048 ko04062 Chemokine signaling pathway 13/177 201/7206 0.00129189358206 ko05031 Amphetamine addiction 8/177 91/7206 0.0016934477107 ko04725 Cholinergic synapse 11/177 160/7206 0.0018720175128 ko05014 Amyotrophic lateral sclerosis (ALS) 7/177 74/7206 0.00215594956111 ko04742 Taste transduction 6/177 61/7206 0.00365815678064 ko04260 Cardiac muscle contraction 7/177 98/7206 0.0101512389391 ko04740 Olfactory transduction 6/177 80/7206 0.0135223371531 ko04261 Adrenergic signaling in cardiomyocytes 11/177 205/7206 0.0176434710079 ko04810 Regulation of actin cytoskeleton 1/177 264/7206 0.0227341160092 ko04014 Ras signaling pathway 13/177 279/7206 0.0266018812626 ko04970 Salivary secretion 6/177 95/7206 0.02901714065 ko04964 Proximal tubule bicarbonate reclamation 3/177 29/7206 0.0333405370356 ko04720 Long-term potentiation 6/177 99/7206 0.0345628545806 ko04976 Bile secretion 5/177 80/7206 0.0463784653581