ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 18/138 191/7206 1.87115412589e-08 ko04621 NOD-like receptor signaling pathway 15/138 157/7206 2.61451940792e-07 ko05131 Shigellosis 11/138 82/7206 3.73941286285e-07 ko05164 Influenza A 14/138 167/7206 3.25253560774e-06 ko05132 Salmonella infection 9/138 98/7206 9.90756971546e-05 ko04657 IL-17 signaling pathway 8/138 87/7206 0.000241499375533 ko05162 Measles 9/138 120/7206 0.000461418990032 ko04668 TNF signaling pathway 9/138 120/7206 0.000461418990032 ko05100 Bacterial invasion of epithelial cells 8/138 99/7206 0.000583708160919 ko04620 Toll-like receptor signaling pathway 8/138 100/7206 0.00062438272832 ko05160 Hepatitis C 10/138 153/7206 0.000669822114865 ko00140 Steroid hormone biosynthesis 5/138 41/7206 0.00103132678879 ko04217 Necroptosis 10/138 178/7206 0.00211903749838 ko04666 Fc gamma R-mediated phagocytosis 8/138 122/7206 0.0022726324975 ko04932 Non-alcoholic fatty liver disease (NAFLD) 10/138 182/7206 0.00249498660474 ko05167 Kaposi's sarcoma-associated herpesvirus infection 10/138 191/7206 0.00353813729507 ko04630 Jak-STAT signaling pathway 8/138 132/7206 0.00370547981461 ko04380 Osteoclast differentiation 8/138 134/7206 0.00406146854826 ko04931 Insulin resistance 8/138 137/7206 0.00464436758464 ko05150 Staphylococcus aureus infection 4/138 36/7206 0.0047157082101 ko05161 Hepatitis B 9/138 173/7206 0.00582387319434 ko04622 RIG-I-like receptor signaling pathway 5/138 62/7206 0.00646548097617 ko05323 Rheumatoid arthritis 6/138 89/7206 0.00700270335822 ko04210 Apoptosis 9/138 180/7206 0.00750202717929 ko04623 Cytosolic DNA-sensing pathway 4/138 41/7206 0.00753233105106 ko05168 Herpes simplex infection 9/138 182/7206 0.00804356634063 ko04660 T cell receptor signaling pathway 7/138 124/7206 0.00951903527306 ko05142 Chagas disease (American trypanosomiasis) 7/138 130/7206 0.0121591043546 ko04068 FoxO signaling pathway 8/138 167/7206 0.0146081013431 ko04062 Chemokine signaling pathway 9/138 201/7206 0.0147932440584 ko05130 Pathogenic Escherichia coli infection 5/138 77/7206 0.0157333495088 ko04610 Complement and coagulation cascades 5/138 79/7206 0.0174140784878 ko04213 Longevity regulating pathway - multiple species 5/138 86/7206 0.0242211017465 ko05133 Pertussis 5/138 87/7206 0.0253152600387 ko04662 B cell receptor signaling pathway 5/138 88/7206 0.0264407222159 ko05152 Tuberculosis 8/138 187/7206 0.0268217393303 ko04920 Adipocytokine signaling pathway 5/138 89/7206 0.0275977471478 ko04211 Longevity regulating pathway 6/138 123/7206 0.0303346909464 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/138 92/7206 0.0312605920723 ko01522 Endocrine resistance 6/138 124/7206 0.0313931141159 ko05221 Acute myeloid leukemia 4/138 63/7206 0.0321434170206 ko04672 Intestinal immune network for IgA production 3/138 37/7206 0.0332408211603 ko04064 NF-kappa B signaling pathway 5/138 96/7206 0.0365996825736 ko04650 Natural killer cell mediated cytotoxicity 5/138 97/7206 0.0380169591642 ko04960 Aldosterone-regulated sodium reabsorption 3/138 41/7206 0.0431725345343 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/138 135/7206 0.0446472212271 ko00051 Fructose and mannose metabolism 3/138 42/7206 0.0458624334065 ko04710 Circadian rhythm 3/138 43/7206 0.0486336037215