ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 15/221 96/7206 1.79602463519e-07 ko04060 Cytokine-cytokine receptor interaction 21/221 191/7206 3.20118522149e-07 ko00350 Tyrosine metabolism 9/221 33/7206 4.14441028142e-07 ko00643 Styrene degradation 4/221 4/7206 8.61589110006e-07 ko04064 NF-kappa B signaling pathway 12/221 96/7206 3.30068586935e-05 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/221 4/7206 0.000111287275962 ko00120 Primary bile acid biosynthesis 5/221 20/7206 0.000275792366847 ko04658 Th1 and Th2 cell differentiation 10/221 96/7206 0.000674403645402 ko00140 Steroid hormone biosynthesis 6/221 41/7206 0.00142309814228 ko04659 Th17 cell differentiation 10/221 106/7206 0.00145909360002 ko00360 Phenylalanine metabolism 4/221 17/7206 0.00149590524556 ko04630 Jak-STAT signaling pathway 11/221 132/7206 0.00234427208978 ko00950 Isoquinoline alkaloid biosynthesis 3/221 10/7206 0.00291101781842 ko00100 Steroid biosynthesis 4/221 21/7206 0.00341663860843 ko04657 IL-17 signaling pathway 8/221 87/7206 0.00502497270013 ko04672 Intestinal immune network for IgA production 5/221 37/7206 0.00507593885327 ko05321 Inflammatory bowel disease (IBD) 6/221 56/7206 0.00702200946998 ko04380 Osteoclast differentiation 10/221 134/7206 0.00794942480766 ko04621 NOD-like receptor signaling pathway 11/221 157/7206 0.00870212947701 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/221 5/7206 0.0088080054404 ko04650 Natural killer cell mediated cytotoxicity 8/221 97/7206 0.00958284739481 ko04710 Circadian rhythm 5/221 43/7206 0.0096649309995 ko04360 Axon guidance 1/221 233/7206 0.0105771792608 ko05340 Primary immunodeficiency 4/221 30/7206 0.0126175180797 ko00380 Tryptophan metabolism 5/221 50/7206 0.0179111487533 ko04662 B cell receptor signaling pathway 7/221 88/7206 0.0180191405635 ko04972 Pancreatic secretion 8/221 111/7206 0.0203818283059 ko04975 Fat digestion and absorption 4/221 35/7206 0.0214120533017 ko00740 Riboflavin metabolism 2/221 8/7206 0.0232075371886 ko00401 Novobiocin biosynthesis 1/221 1/7206 0.0306688870386 ko05162 Measles 8/221 120/7206 0.0307688403079 ko00920 Sulfur metabolism 2/221 10/7206 0.0358255673108 ko05164 Influenza A 10/221 167/7206 0.0375206686607 ko00330 Arginine and proline metabolism 5/221 61/7206 0.0384589495877 ko00051 Fructose and mannose metabolism 4/221 42/7206 0.0388171711686 ko00983 Drug metabolism - other enzymes 4/221 42/7206 0.0388171711686 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/221 11/7206 0.0429173100014 ko05161 Hepatitis B 10/221 173/7206 0.0440164744416 ko04723 Retrograde endocannabinoid signaling 1/221 175/7206 0.0452822425031