ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 21/209 79/7206 3.20886744005e-15 ko04974 Protein digestion and absorption 14/209 96/7206 5.65635949481e-07 ko00380 Tryptophan metabolism 10/209 50/7206 1.26618765848e-06 ko04976 Bile secretion 11/209 80/7206 1.70029836484e-05 ko00140 Steroid hormone biosynthesis 8/209 41/7206 1.83497386739e-05 ko00830 Retinol metabolism 8/209 42/7206 2.21087367847e-05 ko00350 Tyrosine metabolism 7/209 33/7206 3.51007129999e-05 ko04975 Fat digestion and absorption 7/209 35/7206 5.25925902411e-05 ko05204 Chemical carcinogenesis 8/209 48/7206 6.08630764652e-05 ko00260 Glycine, serine and threonine metabolism 8/209 48/7206 6.08630764652e-05 ko04972 Pancreatic secretion 12/209 111/7206 8.1529449581e-05 ko00643 Styrene degradation 3/209 4/7206 9.41718929087e-05 ko04614 Renin-angiotensin system 5/209 18/7206 0.000123142461535 ko04978 Mineral absorption 7/209 40/7206 0.000128918385108 ko00120 Primary bile acid biosynthesis 5/209 20/7206 0.000212515049489 ko04977 Vitamin digestion and absorption 5/209 22/7206 0.00034427589151 ko05150 Staphylococcus aureus infection 6/209 36/7206 0.000521134196198 ko00630 Glyoxylate and dicarboxylate metabolism 6/209 38/7206 0.000703818327703 ko00980 Metabolism of xenobiotics by cytochrome P450 6/209 40/7206 0.000932503497031 ko00983 Drug metabolism - other enzymes 6/209 42/7206 0.00121448539653 ko04913 Ovarian steroidogenesis 7/209 63/7206 0.00217765544239 ko00591 Linoleic acid metabolism 4/209 22/7206 0.00333539028444 ko00982 Drug metabolism - cytochrome P450 5/209 37/7206 0.00400382080216 ko00250 Alanine, aspartate and glutamate metabolism 5/209 38/7206 0.00450382117704 ko00340 Histidine metabolism 4/209 25/7206 0.00538931199803 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/209 5/7206 0.00790206772586 ko04964 Proximal tubule bicarbonate reclamation 4/209 29/7206 0.00924575719666 ko00360 Phenylalanine metabolism 3/209 17/7206 0.0121101732131 ko04270 Vascular smooth muscle contraction 10/209 154/7206 0.013858477936 ko03320 PPAR signaling pathway 6/209 69/7206 0.0145576150493 ko04360 Axon guidance 1/209 233/7206 0.0153429287388 ko05034 Alcoholism 1/209 238/7206 0.0158869333581 ko00670 One carbon pool by folate 3/209 20/7206 0.0190501493971 ko00100 Steroid biosynthesis 3/209 21/7206 0.021759915746 ko05016 Huntington's disease 1/209 215/7206 0.0218899993167 ko01524 Platinum drug resistance 6/209 76/7206 0.0224961742641 ko04923 Regulation of lipolysis in adipocytes 6/209 77/7206 0.0238281878906 ko00053 Ascorbate and aldarate metabolism 3/209 22/7206 0.0246690513453 ko02010 ABC transporters 4/209 39/7206 0.0255949925731 ko05203 Viral carcinogenesis 2/209 277/7206 0.0258476738479 ko04611 Platelet activation 10/209 163/7206 0.0276983055399 ko00401 Novobiocin biosynthesis 1/209 1/7206 0.0290036081045 ko00920 Sulfur metabolism 2/209 10/7206 0.0323186716205 ko04973 Carbohydrate digestion and absorption 4/209 42/7206 0.0325829364793 ko04924 Renin secretion 6/209 86/7206 0.038235202274 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/209 11/7206 0.0387582976818 ko05133 Pertussis 6/209 87/7206 0.0401157902148 ko00620 Pyruvate metabolism 4/209 46/7206 0.043475867657 ko04146 Peroxisome 6/209 89/7206 0.0440506735997 ko04390 Hippo signaling pathway 1/209 188/7206 0.045424203444 ko04060 Cytokine-cytokine receptor interaction 1/209 191/7206 0.0458457970431 ko00270 Cysteine and methionine metabolism 4/209 47/7206 0.0464821403854 ko05166 HTLV-I infection 3/209 292/7206 0.0491278212703 ko05200 Pathways in cancer 7/209 492/7206 0.049489898801