ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 25/373 96/7206 8.18568361778e-12 ko04610 Complement and coagulation cascades 20/373 79/7206 1.82794863108e-09 ko04978 Mineral absorption 12/373 40/7206 4.6382927893e-07 ko04976 Bile secretion 16/373 80/7206 2.47077838052e-06 ko04614 Renin-angiotensin system 7/373 18/7206 1.82325028224e-05 ko04977 Vitamin digestion and absorption 7/373 22/7206 8.15715262717e-05 ko04740 Olfactory transduction 13/373 80/7206 0.000207141868309 ko00983 Drug metabolism - other enzymes 9/373 42/7206 0.000235479386655 ko04975 Fat digestion and absorption 8/373 35/7206 0.00032775091384 ko00830 Retinol metabolism 8/373 42/7206 0.00119653313473 ko04080 Neuroactive ligand-receptor interaction 37/373 423/7206 0.0014175434059 ko04260 Cardiac muscle contraction 13/373 98/7206 0.00151900199095 ko05161 Hepatitis B 1/373 173/7206 0.0015493927307 ko04972 Pancreatic secretion 14/373 111/7206 0.00166302615439 ko05410 Hypertrophic cardiomyopathy (HCM) 13/373 100/7206 0.00183052682605 ko05203 Viral carcinogenesis 4/373 277/7206 0.00203278483848 ko05033 Nicotine addiction 9/373 56/7206 0.00210814713836 ko03013 RNA transport 1/373 166/7206 0.0022607299467 ko05204 Chemical carcinogenesis 8/373 48/7206 0.00291746045833 ko04742 Taste transduction 9/373 61/7206 0.00384339571859 ko04060 Cytokine-cytokine receptor interaction 2/373 191/7206 0.00433037296378 ko00591 Linoleic acid metabolism 5/373 22/7206 0.00458545234737 ko04621 NOD-like receptor signaling pathway 1/373 157/7206 0.00510894307447 ko04390 Hippo signaling pathway 2/373 188/7206 0.00649068471329 ko04919 Thyroid hormone signaling pathway 1/373 143/7206 0.00697882358266 ko03040 Spliceosome 1/373 145/7206 0.00702569047941 ko04512 ECM-receptor interaction 10/373 79/7206 0.00722646515853 ko00620 Pyruvate metabolism 7/373 46/7206 0.00877159670782 ko05150 Staphylococcus aureus infection 6/373 36/7206 0.00961255738723 ko05166 HTLV-I infection 6/373 292/7206 0.00992820342571 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/373 135/7206 0.0101275678349 ko04120 Ubiquitin mediated proteolysis 1/373 138/7206 0.0102500901461 ko00982 Drug metabolism - cytochrome P450 6/373 37/7206 0.0109863090735 ko04072 Phospholipase D signaling pathway 3/373 197/7206 0.0135223957176 ko00380 Tryptophan metabolism 7/373 50/7206 0.0137229199856 ko04062 Chemokine signaling pathway 3/373 201/7206 0.0139384793175 ko05200 Pathways in cancer 14/373 492/7206 0.0147546485667 ko04964 Proximal tubule bicarbonate reclamation 5/373 29/7206 0.0153693052647 ko00980 Metabolism of xenobiotics by cytochrome P450 6/373 40/7206 0.0159319805051 ko00590 Arachidonic acid metabolism 7/373 52/7206 0.0168336881513 ko00140 Steroid hormone biosynthesis 6/373 41/7206 0.0178751015212 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 9/373 79/7206 0.0202255522342 ko05162 Measles 1/373 120/7206 0.0212130832628 ko00480 Glutathione metabolism 7/373 55/7206 0.0223869863583 ko00053 Ascorbate and aldarate metabolism 4/373 22/7206 0.0246291005255 ko04217 Necroptosis 3/373 178/7206 0.0257753207452 ko04310 Wnt signaling pathway 3/373 181/7206 0.0258629472855 ko00350 Tyrosine metabolism 5/373 33/7206 0.0259620918643 ko05168 Herpes simplex infection 3/373 182/7206 0.0259830763098 ko04150 mTOR signaling pathway 3/373 184/7206 0.026359799346 ko04141 Protein processing in endoplasmic reticulum 3/373 184/7206 0.026359799346 ko04725 Cholinergic synapse 15/373 160/7206 0.0274261758404 ko04727 GABAergic synapse 11/373 110/7206 0.0292647159247 ko05032 Morphine addiction 11/373 110/7206 0.0292647159247 ko04144 Endocytosis 9/373 342/7206 0.0322085208358 ko00410 beta-Alanine metabolism 5/373 35/7206 0.0326608505116 ko00770 Pantothenate and CoA biosynthesis 3/373 14/7206 0.0327085945095 ko04360 Axon guidance 5/373 233/7206 0.0336998740246 ko05169 Epstein-Barr virus infection 4/373 206/7206 0.0357926844021 ko00260 Glycine, serine and threonine metabolism 6/373 48/7206 0.0361228022728 ko04218 Cellular senescence 3/373 177/7206 0.0365796932316 ko00340 Histidine metabolism 4/373 25/7206 0.0377333745955 ko01200 Carbon metabolism 12/373 128/7206 0.0412663788339 ko04924 Renin secretion 9/373 86/7206 0.0430947495484 ko04914 Progesterone-mediated oocyte maturation 1/373 104/7206 0.0440379585972 ko04659 Th17 cell differentiation 1/373 106/7206 0.0442924305288 ko01521 EGFR tyrosine kinase inhibitor resistance 1/373 106/7206 0.0442924305288 ko00250 Alanine, aspartate and glutamate metabolism 5/373 38/7206 0.0445658825491 ko04140 Autophagy - animal 3/373 164/7206 0.0485702695304 ko04550 Signaling pathways regulating pluripotency of stem cells 3/373 165/7206 0.0487193253124 ko02010 ABC transporters 5/373 39/7206 0.0490402809156 ko04114 Oocyte meiosis 2/373 139/7206 0.0495331049099