ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 17/231 96/7206 7.25692932896e-09 ko00643 Styrene degradation 4/231 4/7206 1.02966223265e-06 ko00380 Tryptophan metabolism 10/231 50/7206 3.14117606416e-06 ko00350 Tyrosine metabolism 8/231 33/7206 6.85547510201e-06 ko00680 Methane metabolism 8/231 34/7206 8.71952836482e-06 ko01200 Carbon metabolism 15/231 128/7206 1.29634173648e-05 ko00010 Glycolysis / Gluconeogenesis 11/231 74/7206 2.03703231062e-05 ko00140 Steroid hormone biosynthesis 8/231 41/7206 3.77952067052e-05 ko04610 Complement and coagulation cascades 11/231 79/7206 3.82435090306e-05 ko00830 Retinol metabolism 8/231 42/7206 4.54135015238e-05 ko05204 Chemical carcinogenesis 8/231 48/7206 0.000122992716776 ko04614 Renin-angiotensin system 5/231 18/7206 0.000197300257675 ko00980 Metabolism of xenobiotics by cytochrome P450 7/231 40/7206 0.000239874126655 ko00120 Primary bile acid biosynthesis 5/231 20/7206 0.000338755369268 ko00620 Pyruvate metabolism 7/231 46/7206 0.000584824994283 ko04972 Pancreatic secretion 11/231 111/7206 0.000813577971646 ko04976 Bile secretion 9/231 80/7206 0.000977596532168 ko00230 Purine metabolism 15/231 194/7206 0.001363510218 ko01230 Biosynthesis of amino acids 9/231 85/7206 0.00151122963165 ko00360 Phenylalanine metabolism 4/231 17/7206 0.00176177390919 ko05133 Pertussis 9/231 87/7206 0.00178127463132 ko05134 Legionellosis 8/231 74/7206 0.00240271441535 ko00030 Pentose phosphate pathway 5/231 32/7206 0.00321611484219 ko04512 ECM-receptor interaction 8/231 79/7206 0.00362749661608 ko00052 Galactose metabolism 5/231 33/7206 0.00369318895755 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/231 11/7206 0.00443336280418 ko05410 Hypertrophic cardiomyopathy (HCM) 9/231 100/7206 0.00461429173803 ko04022 cGMP-PKG signaling pathway 15/231 216/7206 0.00466415471744 ko04510 Focal adhesion 16/231 240/7206 0.00466879887424 ko00630 Glyoxylate and dicarboxylate metabolism 5/231 38/7206 0.00686118813535 ko05034 Alcoholism 1/231 238/7206 0.0074199675396 ko00340 Histidine metabolism 4/231 25/7206 0.00766018486567 ko00040 Pentose and glucuronate interconversions 4/231 26/7206 0.00882961006398 ko04014 Ras signaling pathway 2/231 279/7206 0.00889162264191 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/231 5/7206 0.00959793377619 ko05160 Hepatitis C 11/231 153/7206 0.00991294931193 ko00983 Drug metabolism - other enzymes 5/231 42/7206 0.010486748392 ko00720 Carbon fixation pathways in prokaryotes 3/231 17/7206 0.0158557602258 ko04270 Vascular smooth muscle contraction 11/231 154/7206 0.0166493721788 ko00260 Glycine, serine and threonine metabolism 5/231 48/7206 0.0180906580379 ko04611 Platelet activation 11/231 163/7206 0.0200627304586 ko04146 Peroxisome 7/231 89/7206 0.0236530417934 ko04975 Fat digestion and absorption 4/231 35/7206 0.0247304610269 ko00670 One carbon pool by folate 3/231 20/7206 0.0247758799061 ko05150 Staphylococcus aureus infection 4/231 36/7206 0.0271433823995 ko00100 Steroid biosynthesis 3/231 21/7206 0.028237498845 ko04371 Apelin signaling pathway 11/231 177/7206 0.0295503954337 ko00982 Drug metabolism - cytochrome P450 4/231 37/7206 0.0296923231505 ko00520 Amino sugar and nucleotide sugar metabolism 5/231 55/7206 0.0307311898768 ko04080 Neuroactive ligand-receptor interaction 6/231 423/7206 0.0314079716763 ko04310 Wnt signaling pathway 1/231 181/7206 0.0314888924106 ko04150 mTOR signaling pathway 1/231 184/7206 0.0316821316754 ko00053 Ascorbate and aldarate metabolism 3/231 22/7206 0.0319420891255 ko00401 Novobiocin biosynthesis 1/231 1/7206 0.0320566194839 ko00250 Alanine, aspartate and glutamate metabolism 4/231 38/7206 0.0323783390341 ko04360 Axon guidance 2/231 233/7206 0.0354067431395 ko04971 Gastric acid secretion 7/231 98/7206 0.0373987277477 ko00920 Sulfur metabolism 2/231 10/7206 0.0388594248159 ko00051 Fructose and mannose metabolism 4/231 42/7206 0.0445054990237 ko00330 Arginine and proline metabolism 5/231 61/7206 0.0451232551398 ko05224 Breast cancer 1/231 174/7206 0.0460699435631 ko04723 Retrograde endocannabinoid signaling 1/231 175/7206 0.0463542015414