ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	158/912	423/7206	2.80703120225e-41
ko04724	Glutamatergic synapse	73/912	152/7206	4.03058190089e-27
ko05033	Nicotine addiction	42/912	56/7206	8.47244151093e-27
ko05032	Morphine addiction	55/912	110/7206	9.75284184327e-22
ko04727	GABAergic synapse	53/912	110/7206	4.84975945923e-20
ko04728	Dopaminergic synapse	71/912	185/7206	2.09378304126e-19
ko04024	cAMP signaling pathway	89/912	279/7206	7.00252121604e-18
ko04723	Retrograde endocannabinoid signaling	66/912	175/7206	1.20202887878e-17
ko04713	Circadian entrainment	56/912	136/7206	3.68000460729e-17
ko04725	Cholinergic synapse	61/912	160/7206	1.17865010797e-16
ko04721	Synaptic vesicle cycle	37/912	80/7206	1.18669571503e-13
ko04020	Calcium signaling pathway	76/912	265/7206	1.21535267458e-12
ko04726	Serotonergic synapse	49/912	137/7206	2.181751894e-12
ko04911	Insulin secretion	44/912	117/7206	4.13559435393e-12
ko04360	Axon guidance	68/912	233/7206	8.0203301128e-12
ko04921	Oxytocin signaling pathway	58/912	209/7206	2.53719124632e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/912	205/7206	3.30746532942e-09
ko03040	Spliceosome	1/912	145/7206	9.05052477684e-08
ko05031	Amphetamine addiction	31/912	91/7206	9.40970919658e-08
ko04742	Taste transduction	24/912	61/7206	1.22276068193e-07
ko05030	Cocaine addiction	26/912	73/7206	3.78707713755e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/912	74/7206	5.14796333881e-07
ko05203	Viral carcinogenesis	11/912	277/7206	7.57979543996e-07
ko04010	MAPK signaling pathway	71/912	321/7206	1.73282206076e-06
ko04720	Long-term potentiation	30/912	99/7206	3.94531244825e-06
ko04514	Cell adhesion molecules (CAMs)	35/912	130/7206	1.16816181548e-05
ko04972	Pancreatic secretion	31/912	111/7206	1.60329007103e-05
ko03013	RNA transport	5/912	166/7206	2.53028907078e-05
ko05322	Systemic lupus erythematosus	4/912	151/7206	3.05108934923e-05
ko04970	Salivary secretion	27/912	95/7206	3.19508976044e-05
ko04925	Aldosterone synthesis and secretion	29/912	105/7206	3.73784888403e-05
ko04022	cGMP-PKG signaling pathway	49/912	216/7206	3.95018501906e-05
ko05168	Herpes simplex infection	7/912	182/7206	6.3265527509e-05
ko04971	Gastric acid secretion	27/912	98/7206	7.83701757717e-05
ko05164	Influenza A	6/912	167/7206	8.13439351025e-05
ko04730	Long-term depression	23/912	78/7206	8.50954485218e-05
ko04072	Phospholipase D signaling pathway	44/912	197/7206	0.000121133048475
ko04014	Ras signaling pathway	57/912	279/7206	0.000210479768563
ko04540	Gap junction	31/912	128/7206	0.000252091055451
ko04744	Phototransduction	13/912	36/7206	0.00027407414945
ko04610	Complement and coagulation cascades	1/912	79/7206	0.000488969464783
ko03008	Ribosome biogenesis in eukaryotes	1/912	79/7206	0.000488969464783
ko04141	Protein processing in endoplasmic reticulum	9/912	184/7206	0.000656933288126
ko04070	Phosphatidylinositol signaling system	27/912	112/7206	0.000794707919216
ko04060	Cytokine-cytokine receptor interaction	10/912	191/7206	0.000853622794619
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/912	79/7206	0.00182474461553
ko04915	Estrogen signaling pathway	29/912	131/7206	0.00208508642651
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/912	59/7206	0.00241739184063
ko04071	Sphingolipid signaling pathway	34/912	162/7206	0.00256389367394
ko04260	Cardiac muscle contraction	23/912	98/7206	0.00309303167076
ko04640	Hematopoietic cell lineage	1/912	64/7206	0.00368589346257
ko04120	Ubiquitin mediated proteolysis	7/912	138/7206	0.00421226501072
ko04612	Antigen processing and presentation	2/912	77/7206	0.00488480576095
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/912	14/7206	0.00492352660141
ko04918	Thyroid hormone synthesis	20/912	86/7206	0.00529087916088
ko04146	Peroxisome	3/912	89/7206	0.00554789428952
ko05205	Proteoglycans in cancer	20/912	271/7206	0.00666426605754
ko04621	NOD-like receptor signaling pathway	9/912	157/7206	0.00706222714123
ko04964	Proximal tubule bicarbonate reclamation	9/912	29/7206	0.0075763303598
ko04015	Rap1 signaling pathway	50/912	278/7206	0.00966487763654
ko04371	Apelin signaling pathway	34/912	177/7206	0.0113926276015
ko04217	Necroptosis	12/912	178/7206	0.015850126377
ko04711	Circadian rhythm - fly	5/912	13/7206	0.0172377382708
ko00240	Pyrimidine metabolism	6/912	110/7206	0.0198501158216
ko00330	Arginine and proline metabolism	2/912	61/7206	0.019977980568
ko05414	Dilated cardiomyopathy	23/912	112/7206	0.020564763103
ko04930	Type II diabetes mellitus	13/912	54/7206	0.0208791565192
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/912	182/7206	0.0232381247419
ko03420	Nucleotide excision repair	1/912	46/7206	0.0250470570775
ko04976	Bile secretion	17/912	80/7206	0.0269561038672
ko05131	Shigellosis	4/912	82/7206	0.0292628981658
ko03018	RNA degradation	4/912	84/7206	0.0299520570194
ko01200	Carbon metabolism	8/912	128/7206	0.0305333211868
ko04110	Cell cycle	10/912	145/7206	0.0318824480185
ko04960	Aldosterone-regulated sodium reabsorption	10/912	41/7206	0.0323587236363
ko05169	Epstein-Barr virus infection	16/912	206/7206	0.0328641910711
ko03022	Basal transcription factors	1/912	44/7206	0.0374467036774
ko04923	Regulation of lipolysis in adipocytes	16/912	77/7206	0.0380663619728
ko04966	Collecting duct acid secretion	7/912	26/7206	0.0382917538752
ko00071	Fatty acid degradation	1/912	45/7206	0.0386529125125
ko00480	Glutathione metabolism	2/912	55/7206	0.0406894629748
ko05321	Inflammatory bowel disease (IBD)	2/912	56/7206	0.041141458864
ko05231	Choline metabolism in cancer	25/912	134/7206	0.0476359396671
ko04745	Phototransduction - fly	9/912	38/7206	0.0494706684694