ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	109/796	423/7206	1.4298404487e-18
ko05033	Nicotine addiction	32/796	56/7206	4.37771620012e-17
ko04724	Glutamatergic synapse	47/796	152/7206	1.6465239646e-11
ko04727	GABAergic synapse	34/796	110/7206	1.12036087939e-08
ko04728	Dopaminergic synapse	47/796	185/7206	2.9369621839e-08
ko04713	Circadian entrainment	37/796	136/7206	1.09241760218e-07
ko04261	Adrenergic signaling in cardiomyocytes	48/796	205/7206	3.2629627973e-07
ko04514	Cell adhesion molecules (CAMs)	35/796	130/7206	5.31348794076e-07
ko04911	Insulin secretion	32/796	117/7206	6.96782171891e-07
ko04974	Protein digestion and absorption	28/796	96/7206	8.42318057219e-07
ko03040	Spliceosome	1/796	145/7206	1.32263173572e-06
ko04260	Cardiac muscle contraction	28/796	98/7206	1.33399959353e-06
ko05032	Morphine addiction	30/796	110/7206	1.65541495793e-06
ko04723	Retrograde endocannabinoid signaling	41/796	175/7206	2.05895598311e-06
ko04721	Synaptic vesicle cycle	24/796	80/7206	2.94945534167e-06
ko04950	Maturity onset diabetes of the young	13/796	29/7206	4.14753610813e-06
ko04725	Cholinergic synapse	38/796	160/7206	4.36100518353e-06
ko04060	Cytokine-cytokine receptor interaction	4/796	191/7206	5.5105177067e-06
ko04512	ECM-receptor interaction	23/796	79/7206	8.28264872912e-06
ko05203	Viral carcinogenesis	10/796	277/7206	8.5000957665e-06
ko04976	Bile secretion	23/796	80/7206	1.04346390434e-05
ko04024	cAMP signaling pathway	55/796	279/7206	1.43031208658e-05
ko04010	MAPK signaling pathway	61/796	321/7206	1.54517104925e-05
ko04742	Taste transduction	19/796	61/7206	1.74599980396e-05
ko05162	Measles	1/796	120/7206	2.26688358268e-05
ko05030	Cocaine addiction	21/796	73/7206	2.48990194085e-05
ko04120	Ubiquitin mediated proteolysis	2/796	138/7206	2.55063534099e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/796	74/7206	3.12187048504e-05
ko03013	RNA transport	4/796	166/7206	4.7152771679e-05
ko05164	Influenza A	4/796	167/7206	4.74938130376e-05
ko04360	Axon guidance	46/796	233/7206	7.0091490168e-05
ko04964	Proximal tubule bicarbonate reclamation	11/796	29/7206	0.00014763099966
ko05168	Herpes simplex infection	6/796	182/7206	0.000179732911616
ko04978	Mineral absorption	13/796	40/7206	0.000230953906948
ko00564	Glycerophospholipid metabolism	1/796	99/7206	0.000256491172712
ko05410	Hypertrophic cardiomyopathy (HCM)	24/796	100/7206	0.000270266496348
ko05031	Amphetamine addiction	22/796	91/7206	0.000298682058957
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/796	79/7206	0.000360572351662
ko04726	Serotonergic synapse	29/796	137/7206	0.000476282738824
ko04151	PI3K-Akt signaling pathway	65/796	390/7206	0.000612772539037
ko04970	Salivary secretion	22/796	95/7206	0.000704608760838
ko04141	Protein processing in endoplasmic reticulum	7/796	184/7206	0.000726425160293
ko04610	Complement and coagulation cascades	19/796	79/7206	0.000849668047549
ko04140	Autophagy - animal	6/796	164/7206	0.000937723729867
ko04217	Necroptosis	7/796	178/7206	0.000964534273955
ko05166	HTLV-I infection	16/796	292/7206	0.00111866906558
ko05414	Dilated cardiomyopathy	24/796	112/7206	0.00119704000491
ko04924	Renin secretion	20/796	86/7206	0.00135043960655
ko04921	Oxytocin signaling pathway	38/796	209/7206	0.00162602723897
ko03008	Ribosome biogenesis in eukaryotes	1/796	79/7206	0.00175685959213
ko04621	NOD-like receptor signaling pathway	6/796	157/7206	0.00179434499818
ko04740	Olfactory transduction	18/796	80/7206	0.00322064856356
ko04142	Lysosome	6/796	151/7206	0.00347396901581
ko04110	Cell cycle	6/796	145/7206	0.0045991971706
ko04730	Long-term depression	17/796	78/7206	0.00542170871729
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/796	182/7206	0.00554651004779
ko04150	mTOR signaling pathway	9/796	184/7206	0.0056836224083
ko05169	Epstein-Barr virus infection	11/796	206/7206	0.00641043823933
ko04137	Mitophagy - animal	2/796	82/7206	0.00718036813523
ko04138	Autophagy - yeast	2/796	81/7206	0.00718120727253
ko04218	Cellular senescence	9/796	177/7206	0.00732833892102
ko03018	RNA degradation	2/796	84/7206	0.00744231309699
ko05016	Huntington's disease	12/796	215/7206	0.00765125486715
ko04211	Longevity regulating pathway	5/796	123/7206	0.00861552548159
ko05161	Hepatitis B	9/796	173/7206	0.00968177369818
ko00561	Glycerolipid metabolism	1/796	63/7206	0.0130670242776
ko00600	Sphingolipid metabolism	1/796	63/7206	0.0130670242776
ko00430	Taurine and hypotaurine metabolism	5/796	14/7206	0.01386823777
ko04744	Phototransduction	9/796	36/7206	0.0141085487974
ko04612	Antigen processing and presentation	2/796	77/7206	0.0154871568387
ko04062	Chemokine signaling pathway	12/796	201/7206	0.0163973742619
ko04914	Progesterone-mediated oocyte maturation	4/796	104/7206	0.0166941675053
ko05322	Systemic lupus erythematosus	8/796	151/7206	0.018128375925
ko04022	cGMP-PKG signaling pathway	35/796	216/7206	0.0199598161357
ko00190	Oxidative phosphorylation	6/796	127/7206	0.0210869839413
ko04214	Apoptosis - fly	2/796	72/7206	0.0213853753964
ko05152	Tuberculosis	11/796	187/7206	0.0237760129401
ko04011	MAPK signaling pathway - yeast	1/796	53/7206	0.0263414118371
ko00280	Valine, leucine and isoleucine degradation	1/796	54/7206	0.0266946206534
ko04020	Calcium signaling pathway	41/796	265/7206	0.0273409626075
ko00520	Amino sugar and nucleotide sugar metabolism	1/796	55/7206	0.027398739526
ko04210	Apoptosis	11/796	180/7206	0.0298870472608
ko00240	Pyrimidine metabolism	5/796	110/7206	0.0301249816642
ko04540	Gap junction	22/796	128/7206	0.0320396977463
ko04630	Jak-STAT signaling pathway	7/796	132/7206	0.0343106243471
ko05012	Parkinson's disease	9/796	155/7206	0.037088130602
ko00380	Tryptophan metabolism	1/796	50/7206	0.0388303041902
ko04144	Endocytosis	26/796	342/7206	0.0414713961417
ko04640	Hematopoietic cell lineage	2/796	64/7206	0.0427963526028
ko01524	Platinum drug resistance	3/796	76/7206	0.0429574074475
ko04972	Pancreatic secretion	19/796	111/7206	0.0466495883993