ko pathway ratio_in_study ratio_in_pop p_value ko04020 Calcium signaling pathway 4/12 265/7206 0.000700641013877 ko04972 Pancreatic secretion 3/12 111/7206 0.00070725493377 ko04911 Insulin secretion 3/12 117/7206 0.000824745050432 ko04924 Renin secretion 2/12 86/7206 0.00859758209286 ko04918 Thyroid hormone synthesis 2/12 86/7206 0.00859758209286 ko04970 Salivary secretion 2/12 95/7206 0.0104158843483 ko04971 Gastric acid secretion 2/12 98/7206 0.0110570142098 ko04925 Aldosterone synthesis and secretion 2/12 105/7206 0.0126197900571 ko04070 Phosphatidylinositol signaling system 2/12 112/7206 0.0142744792565 ko04912 GnRH signaling pathway 2/12 122/7206 0.0167938585953 ko04750 Inflammatory mediator regulation of TRP channels 2/12 122/7206 0.0167938585953 ko04922 Glucagon signaling pathway 2/12 128/7206 0.0183912374076 ko04540 Gap junction 2/12 128/7206 0.0183912374076 ko04915 Estrogen signaling pathway 2/12 131/7206 0.0192135668199 ko04713 Circadian entrainment 2/12 136/7206 0.0206186229483 ko04114 Oocyte meiosis 2/12 139/7206 0.0214821200822 ko04724 Glutamatergic synapse 2/12 152/7206 0.0253973537917 ko04270 Vascular smooth muscle contraction 2/12 154/7206 0.0260242277001 ko04725 Cholinergic synapse 2/12 160/7206 0.0279432102956 ko04611 Platelet activation 2/12 163/7206 0.0289240211958 ko04723 Retrograde endocannabinoid signaling 2/12 175/7206 0.0329861446017 ko04371 Apelin signaling pathway 2/12 177/7206 0.0336843640333 ko00230 Purine metabolism 2/12 194/7206 0.0398554054772 ko04921 Oxytocin signaling pathway 2/12 209/7206 0.0456380916506 ko04022 cGMP-PKG signaling pathway 2/12 216/7206 0.0484402055074