ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 31/259 79/7206 5.35623254329e-25 ko04950 Maturity onset diabetes of the young 15/259 29/7206 7.14569943365e-15 ko04975 Fat digestion and absorption 14/259 35/7206 5.00624162392e-12 ko00260 Glycine, serine and threonine metabolism 13/259 48/7206 7.76022642212e-09 ko05150 Staphylococcus aureus infection 9/259 36/7206 3.49937275333e-06 ko04977 Vitamin digestion and absorption 7/259 22/7206 7.66907373816e-06 ko01200 Carbon metabolism 14/259 128/7206 0.000187580079708 ko00472 D-Arginine and D-ornithine metabolism 3/259 5/7206 0.00043501492272 ko00311 Penicillin and cephalosporin biosynthesis 3/259 5/7206 0.00043501492272 ko03320 PPAR signaling pathway 9/259 69/7206 0.000746768268448 ko01230 Biosynthesis of amino acids 10/259 85/7206 0.000878632822712 ko04931 Insulin resistance 13/259 137/7206 0.00123783444713 ko00330 Arginine and proline metabolism 8/259 61/7206 0.00141090881112 ko04512 ECM-receptor interaction 9/259 79/7206 0.00198484755081 ko00040 Pentose and glucuronate interconversions 5/259 26/7206 0.0020413857797 ko04974 Protein digestion and absorption 10/259 96/7206 0.00224165963309 ko00710 Carbon fixation in photosynthetic organisms 5/259 27/7206 0.00243294168249 ko04978 Mineral absorption 6/259 40/7206 0.0027932192764 ko00480 Glutathione metabolism 7/259 55/7206 0.00331494079324 ko00983 Drug metabolism - other enzymes 6/259 42/7206 0.00359552171793 ko04146 Peroxisome 9/259 89/7206 0.00449148645034 ko00010 Glycolysis / Gluconeogenesis 8/259 74/7206 0.00483673756242 ko00030 Pentose phosphate pathway 5/259 32/7206 0.00524331607179 ko00270 Cysteine and methionine metabolism 6/259 47/7206 0.00633878139285 ko05169 Epstein-Barr virus infection 1/259 206/7206 0.00718845908941 ko04921 Oxytocin signaling pathway 1/259 209/7206 0.00724292240855 ko05016 Huntington's disease 1/259 215/7206 0.00763696740125 ko00020 Citrate cycle (TCA cycle) 5/259 35/7206 0.00774520262021 ko05217 Basal cell carcinoma 7/259 68/7206 0.0106790389238 ko04062 Chemokine signaling pathway 1/259 201/7206 0.0107262322814 ko05010 Alzheimer's disease 1/259 202/7206 0.0108280957161 ko00232 Caffeine metabolism 2/259 5/7206 0.0119763305759 ko02010 ABC transporters 5/259 39/7206 0.0122304429631 ko00770 Pantothenate and CoA biosynthesis 3/259 14/7206 0.0124488612432 ko05034 Alcoholism 2/259 238/7206 0.0126025838971 ko05020 Prion diseases 5/259 40/7206 0.0135786177756 ko04141 Protein processing in endoplasmic reticulum 1/259 184/7206 0.015090212303 ko00051 Fructose and mannose metabolism 5/259 42/7206 0.0165678145048 ko04973 Carbohydrate digestion and absorption 5/259 42/7206 0.0165678145048 ko04340 Hedgehog signaling pathway 6/259 58/7206 0.017237340999 ko04216 Ferroptosis 5/259 44/7206 0.0199650306945 ko05161 Hepatitis B 1/259 173/7206 0.021793918078 ko04723 Retrograde endocannabinoid signaling 1/259 175/7206 0.0218981321757 ko04080 Neuroactive ligand-receptor interaction 7/259 423/7206 0.0219522255598 ko04217 Necroptosis 1/259 178/7206 0.0222668594942 ko04210 Apoptosis 1/259 180/7206 0.022654706865 ko04614 Renin-angiotensin system 3/259 18/7206 0.0251099460698 ko00564 Glycerophospholipid metabolism 8/259 99/7206 0.0256035490943 ko00052 Galactose metabolism 4/259 33/7206 0.0294277457691 ko04722 Neurotrophin signaling pathway 1/259 160/7206 0.0313957575979 ko04725 Cholinergic synapse 1/259 160/7206 0.0313957575979 ko04140 Autophagy - animal 1/259 164/7206 0.0315686115125 ko04151 PI3K-Akt signaling pathway 22/259 390/7206 0.0344850953552 ko05166 HTLV-I infection 4/259 292/7206 0.0353769985036 ko00500 Starch and sucrose metabolism 4/259 35/7206 0.0356265808706 ko00590 Arachidonic acid metabolism 5/259 52/7206 0.0379742407818 ko04920 Adipocytokine signaling pathway 7/259 89/7206 0.0404372610871 ko00591 Linoleic acid metabolism 3/259 22/7206 0.0426738505146 ko04010 MAPK signaling pathway 5/259 321/7206 0.0447617485621 ko05012 Parkinson's disease 1/259 155/7206 0.0458698308311 ko00250 Alanine, aspartate and glutamate metabolism 4/259 38/7206 0.0462357633061 ko00630 Glyoxylate and dicarboxylate metabolism 4/259 38/7206 0.0462357633061 ko05203 Viral carcinogenesis 4/259 277/7206 0.0474252320138