ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	53/539	152/7206	6.08571564338e-23
ko05032	Morphine addiction	41/539	110/7206	3.40567070496e-19
ko04080	Neuroactive ligand-receptor interaction	84/539	423/7206	1.20895359166e-17
ko04723	Retrograde endocannabinoid signaling	49/539	175/7206	9.54939053664e-17
ko04727	GABAergic synapse	38/539	110/7206	1.42416810418e-16
ko04713	Circadian entrainment	42/539	136/7206	3.51059203627e-16
ko05033	Nicotine addiction	26/539	56/7206	2.33475174426e-15
ko04728	Dopaminergic synapse	47/539	185/7206	2.50395098702e-14
ko04020	Calcium signaling pathway	53/539	265/7206	1.58229876367e-11
ko04911	Insulin secretion	32/539	117/7206	4.88018788479e-11
ko05031	Amphetamine addiction	27/539	91/7206	2.17313413884e-10
ko04024	cAMP signaling pathway	51/539	279/7206	1.40079292162e-09
ko04925	Aldosterone synthesis and secretion	28/539	105/7206	1.5324056548e-09
ko04720	Long-term potentiation	27/539	99/7206	1.75641462992e-09
ko04261	Adrenergic signaling in cardiomyocytes	41/539	205/7206	3.58031308172e-09
ko04725	Cholinergic synapse	35/539	160/7206	4.54739107306e-09
ko04010	MAPK signaling pathway	53/539	321/7206	2.50576883781e-08
ko05030	Cocaine addiction	21/539	73/7206	4.16713467611e-08
ko04742	Taste transduction	19/539	61/7206	4.4741433725e-08
ko04921	Oxytocin signaling pathway	38/539	209/7206	2.62510947377e-07
ko04070	Phosphatidylinositol signaling system	25/539	112/7206	5.08480451164e-07
ko04726	Serotonergic synapse	27/539	137/7206	2.41913028607e-06
ko04072	Phospholipase D signaling pathway	34/539	197/7206	3.14961840256e-06
ko04915	Estrogen signaling pathway	26/539	131/7206	3.2425959409e-06
ko04970	Salivary secretion	21/539	95/7206	4.92047682675e-06
ko04060	Cytokine-cytokine receptor interaction	1/539	191/7206	8.94689655551e-06
ko04912	GnRH signaling pathway	23/539	122/7206	2.86714625555e-05
ko04730	Long-term depression	17/539	78/7206	4.75387288128e-05
ko04022	cGMP-PKG signaling pathway	33/539	216/7206	6.36248406179e-05
ko04740	Olfactory transduction	17/539	80/7206	6.68278706238e-05
ko05414	Dilated cardiomyopathy	21/539	112/7206	6.89828597319e-05
ko04971	Gastric acid secretion	19/539	98/7206	9.51689405008e-05
ko04972	Pancreatic secretion	20/539	111/7206	0.000180779332644
ko00562	Inositol phosphate metabolism	17/539	89/7206	0.000265292058979
ko04371	Apelin signaling pathway	27/539	177/7206	0.000381078811329
ko04540	Gap junction	21/539	128/7206	0.000522799922373
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/539	79/7206	0.000642892416237
ko04750	Inflammatory mediator regulation of TRP channels	20/539	122/7206	0.000725601343981
ko04721	Synaptic vesicle cycle	15/539	80/7206	0.000738066375858
ko05168	Herpes simplex infection	3/539	182/7206	0.000841798772078
ko04923	Regulation of lipolysis in adipocytes	14/539	77/7206	0.00149996426977
ko04918	Thyroid hormone synthesis	15/539	86/7206	0.00159688097069
ko00515	Mannose type O-glycan biosynthesis	7/539	25/7206	0.00184363371295
ko04110	Cell cycle	2/539	145/7206	0.00200763190736
ko03013	RNA transport	3/539	166/7206	0.00240904465593
ko05231	Choline metabolism in cancer	20/539	134/7206	0.00247713422486
ko04062	Chemokine signaling pathway	27/539	201/7206	0.00252433839998
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/539	14/7206	0.00260621155271
ko00513	Various types of N-glycan biosynthesis	9/539	42/7206	0.00327772312872
ko04145	Phagosome	3/539	162/7206	0.00349337915118
ko00512	Mucin type O-glycan biosynthesis	7/539	29/7206	0.0046090983105
ko05203	Viral carcinogenesis	9/539	277/7206	0.00478763448994
ko05034	Alcoholism	30/539	238/7206	0.00531977368477
ko04916	Melanogenesis	20/539	142/7206	0.00543551653042
ko04914	Progesterone-mediated oocyte maturation	16/539	104/7206	0.00702658573909
ko05202	Transcriptional misregulation in cancer	5/539	188/7206	0.00712443290535
ko04270	Vascular smooth muscle contraction	21/539	154/7206	0.0074606185796
ko04211	Longevity regulating pathway	17/539	123/7206	0.0137372464964
ko04014	Ras signaling pathway	32/539	279/7206	0.0142284357077
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	6/539	28/7206	0.0155415098801
ko04744	Phototransduction	7/539	36/7206	0.0156562161371
ko00240	Pyrimidine metabolism	2/539	110/7206	0.0165048565705
ko04930	Type II diabetes mellitus	9/539	54/7206	0.0176043240032
ko04745	Phototransduction - fly	7/539	38/7206	0.0208082294494
ko04114	Oocyte meiosis	18/539	139/7206	0.0210170898028
ko04141	Protein processing in endoplasmic reticulum	6/539	184/7206	0.0227410865819
ko04071	Sphingolipid signaling pathway	20/539	162/7206	0.022907161364
ko04350	TGF-beta signaling pathway	2/539	103/7206	0.02329124594
ko05014	Amyotrophic lateral sclerosis (ALS)	11/539	74/7206	0.0238711774899
ko00190	Oxidative phosphorylation	3/539	127/7206	0.0250315847268
ko04320	Dorso-ventral axis formation	6/539	31/7206	0.0251274605034
ko04015	Rap1 signaling pathway	31/539	278/7206	0.02615373437
ko03008	Ribosome biogenesis in eukaryotes	1/539	79/7206	0.0292376995223
ko00510	N-Glycan biosynthesis	8/539	50/7206	0.0306731795774
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/539	182/7206	0.0307467914682
ko04213	Longevity regulating pathway - multiple species	12/539	86/7206	0.0351938888594
ko04924	Renin secretion	12/539	86/7206	0.0351938888594
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/539	59/7206	0.0399146409944
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/539	26/7206	0.0407313299504
ko04360	Axon guidance	26/539	233/7206	0.0413643640037
ko04012	ErbB signaling pathway	14/539	109/7206	0.0415935554218
ko04630	Jak-STAT signaling pathway	4/539	132/7206	0.045186659764