ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	36/732	56/7206	8.63893216294e-23
ko04080	Neuroactive ligand-receptor interaction	111/732	423/7206	1.32710045219e-22
ko04724	Glutamatergic synapse	56/732	152/7206	5.26482467462e-19
ko04721	Synaptic vesicle cycle	36/732	80/7206	7.32822777995e-16
ko04728	Dopaminergic synapse	57/732	185/7206	3.0458480679e-15
ko04360	Axon guidance	63/732	233/7206	9.391341854e-14
ko04727	GABAergic synapse	38/732	110/7206	2.9339789018e-12
ko04713	Circadian entrainment	43/732	136/7206	3.30221942733e-12
ko05032	Morphine addiction	36/732	110/7206	6.6087945992e-11
ko04723	Retrograde endocannabinoid signaling	46/732	175/7206	6.56025553464e-10
ko04024	cAMP signaling pathway	62/732	279/7206	1.59117401469e-09
ko04725	Cholinergic synapse	41/732	160/7206	1.2769916534e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/732	74/7206	1.26738254885e-07
ko04514	Cell adhesion molecules (CAMs)	34/732	130/7206	1.33307534855e-07
ko05031	Amphetamine addiction	27/732	91/7206	1.66717042748e-07
ko05030	Cocaine addiction	23/732	73/7206	4.18385322213e-07
ko04726	Serotonergic synapse	34/732	137/7206	5.15738038892e-07
ko04911	Insulin secretion	30/732	117/7206	1.15498845606e-06
ko05203	Viral carcinogenesis	7/732	277/7206	1.24554098469e-06
ko03040	Spliceosome	1/732	145/7206	4.80196718272e-06
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/732	14/7206	1.87834699782e-05
ko04261	Adrenergic signaling in cardiomyocytes	40/732	205/7206	4.88104266224e-05
ko04742	Taste transduction	17/732	61/7206	7.90824644827e-05
ko04060	Cytokine-cytokine receptor interaction	5/732	191/7206	8.57847105105e-05
ko04120	Ubiquitin mediated proteolysis	2/732	138/7206	8.66041820482e-05
ko04720	Long-term potentiation	23/732	99/7206	0.00013132865468
ko04010	MAPK signaling pathway	54/732	321/7206	0.000198117525606
ko03013	RNA transport	4/732	166/7206	0.000213528044787
ko05168	Herpes simplex infection	5/732	182/7206	0.000249326755305
ko04621	NOD-like receptor signaling pathway	4/732	157/7206	0.000424577900158
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/732	59/7206	0.000611313805801
ko05164	Influenza A	5/732	167/7206	0.000664482172638
ko04141	Protein processing in endoplasmic reticulum	6/732	184/7206	0.000721553570272
ko05322	Systemic lupus erythematosus	4/732	151/7206	0.000888020490279
ko01200	Carbon metabolism	3/732	128/7206	0.0010330470878
ko00240	Pyrimidine metabolism	2/732	110/7206	0.00120395566342
ko04970	Salivary secretion	20/732	95/7206	0.00157167279923
ko04730	Long-term depression	17/732	78/7206	0.00199974723832
ko04391	Hippo signaling pathway - fly	19/732	90/7206	0.00215296062082
ko03018	RNA degradation	1/732	84/7206	0.00285850823446
ko04921	Oxytocin signaling pathway	35/732	209/7206	0.00334887195602
ko03008	Ribosome biogenesis in eukaryotes	1/732	79/7206	0.00407438596594
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/732	79/7206	0.00720202634093
ko04146	Peroxisome	2/732	89/7206	0.00743135901856
ko04020	Calcium signaling pathway	40/732	265/7206	0.0093737930047
ko04972	Pancreatic secretion	20/732	111/7206	0.0102923486996
ko04966	Collecting duct acid secretion	7/732	26/7206	0.0127248805325
ko04512	ECM-receptor interaction	15/732	79/7206	0.0141934149198
ko04137	Mitophagy - animal	2/732	82/7206	0.0153522740864
ko04022	cGMP-PKG signaling pathway	33/732	216/7206	0.0158339357255
ko04064	NF-kappa B signaling pathway	3/732	96/7206	0.0164154541471
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/732	182/7206	0.0173767714542
ko05210	Colorectal cancer	16/732	86/7206	0.0174237009346
ko05205	Proteoglycans in cancer	16/732	271/7206	0.0178357717015
ko05169	Epstein-Barr virus infection	11/732	206/7206	0.0186344272167
ko00561	Glycerolipid metabolism	1/732	63/7206	0.0188587270043
ko04640	Hematopoietic cell lineage	1/732	64/7206	0.0193765601302
ko04612	Antigen processing and presentation	2/732	77/7206	0.0216423410115
ko04211	Longevity regulating pathway	5/732	123/7206	0.022617444189
ko04964	Proximal tubule bicarbonate reclamation	7/732	29/7206	0.0231181573182
ko04611	Platelet activation	8/732	163/7206	0.0247006644151
ko04540	Gap junction	21/732	128/7206	0.0255997698412
ko04260	Cardiac muscle contraction	17/732	98/7206	0.0267270137625
ko05162	Measles	5/732	120/7206	0.0310388544246
ko00010	Glycolysis / Gluconeogenesis	2/732	74/7206	0.0310744373804
ko05140	Leishmaniasis	2/732	75/7206	0.0316784189857
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/732	8/7206	0.039588319101
ko04974	Protein digestion and absorption	16/732	96/7206	0.0406068373586
ko05321	Inflammatory bowel disease (IBD)	1/732	56/7206	0.0412127985521
ko04014	Ras signaling pathway	39/732	279/7206	0.0423619232563
ko00564	Glycerophospholipid metabolism	4/732	99/7206	0.0428515067915
ko05146	Amoebiasis	4/732	99/7206	0.0428515067915
ko04217	Necroptosis	10/732	178/7206	0.0435434306418
ko04962	Vasopressin-regulated water reabsorption	11/732	58/7206	0.0445074450202
ko01230	Biosynthesis of amino acids	3/732	85/7206	0.0445423967758
ko04140	Autophagy - animal	9/732	164/7206	0.0486404811908