ko pathway ratio_in_study ratio_in_pop p_value ko04921 Oxytocin signaling pathway 13/113 209/7206 2.10649174695e-05 ko04270 Vascular smooth muscle contraction 11/113 154/7206 2.65003584171e-05 ko04371 Apelin signaling pathway 11/113 177/7206 9.5113857004e-05 ko04022 cGMP-PKG signaling pathway 12/113 216/7206 0.000132913276428 ko04922 Glucagon signaling pathway 9/113 128/7206 0.000167160703083 ko04626 Plant-pathogen interaction 3/113 18/7206 0.00258058928947 ko04020 Calcium signaling pathway 11/113 265/7206 0.00282842857864 ko05145 Toxoplasmosis 7/113 126/7206 0.00352607729351 ko04152 AMPK signaling pathway 8/113 161/7206 0.00366453813388 ko04971 Gastric acid secretion 6/113 98/7206 0.00425305973736 ko05410 Hypertrophic cardiomyopathy (HCM) 6/113 100/7206 0.00469660743627 ko04713 Circadian entrainment 7/113 136/7206 0.00536442582728 ko04137 Mitophagy - animal 5/113 82/7206 0.00908427795963 ko04911 Insulin secretion 6/113 117/7206 0.00995197658389 ko04213 Longevity regulating pathway - multiple species 5/113 86/7206 0.0110387164678 ko04066 HIF-1 signaling pathway 6/113 123/7206 0.0125421513462 ko04725 Cholinergic synapse 7/113 160/7206 0.0126263551608 ko04920 Adipocytokine signaling pathway 5/113 89/7206 0.0126807964298 ko04261 Adrenergic signaling in cardiomyocytes 8/113 205/7206 0.0149411471794 ko04068 FoxO signaling pathway 7/113 167/7206 0.0156792606867 ko04745 Phototransduction - fly 3/113 38/7206 0.0212721697758 ko04217 Necroptosis 7/113 178/7206 0.0214879621378 ko04916 Melanogenesis 6/113 142/7206 0.0238177091868 ko04925 Aldosterone synthesis and secretion 5/113 105/7206 0.0242559021898 ko00051 Fructose and mannose metabolism 3/113 42/7206 0.0276772457336 ko05414 Dilated cardiomyopathy 5/113 112/7206 0.0309451542697 ko00660 C5-Branched dibasic acid metabolism 1/113 2/7206 0.031118990016 ko00230 Purine metabolism 7/113 194/7206 0.0323911610927 ko04740 Olfactory transduction 4/113 80/7206 0.0364954710968 ko04024 cAMP signaling pathway 9/113 279/7206 0.0417883285586 ko04912 GnRH signaling pathway 5/113 122/7206 0.0423491677807 ko04611 Platelet activation 6/113 163/7206 0.0425689977245