ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 15/113 80/7206 9.39891258035e-13 ko05120 Epithelial cell signaling in Helicobacter pylori infection 13/113 92/7206 1.36528824308e-09 ko05110 Vibrio cholerae infection 11/113 63/7206 2.67965489682e-09 ko04966 Collecting duct acid secretion 8/113 26/7206 3.51927712863e-09 ko05323 Rheumatoid arthritis 10/113 89/7206 1.08462010587e-06 ko04713 Circadian entrainment 12/113 136/7206 1.22079050433e-06 ko04145 Phagosome 13/113 162/7206 1.2694219969e-06 ko04728 Dopaminergic synapse 13/113 185/7206 5.61823081329e-06 ko04727 GABAergic synapse 10/113 110/7206 7.59668675663e-06 ko05030 Cocaine addiction 8/113 73/7206 1.64173538878e-05 ko04744 Phototransduction 6/113 36/7206 1.72779759164e-05 ko04724 Glutamatergic synapse 11/113 152/7206 2.3445460169e-05 ko00190 Oxidative phosphorylation 10/113 127/7206 2.71111824783e-05 ko05014 Amyotrophic lateral sclerosis (ALS) 7/113 74/7206 0.000146458430991 ko05033 Nicotine addiction 6/113 56/7206 0.000223245841847 ko05032 Morphine addiction 8/113 110/7206 0.000309466230136 ko04723 Retrograde endocannabinoid signaling 10/113 175/7206 0.00039507237194 ko04725 Cholinergic synapse 9/113 160/7206 0.000870211003513 ko04720 Long-term potentiation 7/113 99/7206 0.000878558706405 ko05034 Alcoholism 11/113 238/7206 0.00120586119319 ko04726 Serotonergic synapse 8/113 137/7206 0.00133076208169 ko04014 Ras signaling pathway 12/113 279/7206 0.00134594755515 ko04911 Insulin secretion 7/113 117/7206 0.00232386539366 ko05031 Amphetamine addiction 6/113 91/7206 0.00294176569315 ko04024 cAMP signaling pathway 11/113 279/7206 0.00419300153089 ko04730 Long-term depression 5/113 78/7206 0.00738331159693 ko04142 Lysosome 7/113 151/7206 0.00936409561051 ko04261 Adrenergic signaling in cardiomyocytes 8/113 205/7206 0.0149411471794 ko00430 Taurine and hypotaurine metabolism 2/113 14/7206 0.0196136252205 ko04371 Apelin signaling pathway 7/113 177/7206 0.0209058148372 ko02024 Quorum sensing 2/113 15/7206 0.0224020177502 ko04150 mTOR signaling pathway 7/113 184/7206 0.02521983882 ko04972 Pancreatic secretion 5/113 111/7206 0.0299255309732 ko05167 Kaposi's sarcoma-associated herpesvirus infection 7/113 191/7206 0.0301109841675 ko04626 Plant-pathogen interaction 2/113 18/7206 0.0316640693073 ko04664 Fc epsilon RI signaling pathway 4/113 77/7206 0.0323493107202 ko04062 Chemokine signaling pathway 7/113 201/7206 0.0381560240838 ko04016 MAPK signaling pathway - plant 2/113 20/7206 0.0385337994386 ko04722 Neurotrophin signaling pathway 6/113 160/7206 0.0394508932962 ko04015 Rap1 signaling pathway 9/113 278/7206 0.0413681746333 ko04071 Sphingolipid signaling pathway 6/113 162/7206 0.041512841072 ko04921 Oxytocin signaling pathway 7/113 209/7206 0.0455301056545