ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	71/733	152/7206	1.53863248365e-31
ko05033	Nicotine addiction	39/733	56/7206	1.39765960091e-26
ko04080	Neuroactive ligand-receptor interaction	115/733	423/7206	8.39805403354e-25
ko04713	Circadian entrainment	58/733	136/7206	2.22522800302e-23
ko04728	Dopaminergic synapse	68/733	185/7206	8.76344486724e-23
ko05032	Morphine addiction	48/733	110/7206	4.9157608681e-20
ko04723	Retrograde endocannabinoid signaling	62/733	175/7206	6.83601212895e-20
ko04727	GABAergic synapse	47/733	110/7206	3.52135307773e-19
ko04721	Synaptic vesicle cycle	36/733	80/7206	7.65612394557e-16
ko04744	Phototransduction	23/733	36/7206	6.86000746351e-15
ko04921	Oxytocin signaling pathway	60/733	209/7206	2.15150613674e-14
ko04725	Cholinergic synapse	51/733	160/7206	2.15902352008e-14
ko04024	cAMP signaling pathway	71/733	279/7206	6.97732929836e-14
ko04020	Calcium signaling pathway	67/733	265/7206	7.75909815536e-13
ko04726	Serotonergic synapse	43/733	137/7206	4.56401954885e-12
ko04720	Long-term potentiation	35/733	99/7206	1.05247472873e-11
ko05031	Amphetamine addiction	33/733	91/7206	1.86617857942e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/733	205/7206	1.9383635207e-11
ko04911	Insulin secretion	38/733	117/7206	2.60749749317e-11
ko04060	Cytokine-cytokine receptor interaction	1/733	191/7206	3.61749670591e-08
ko04742	Taste transduction	22/733	61/7206	5.03952086049e-08
ko04925	Aldosterone synthesis and secretion	29/733	105/7206	3.31317089828e-07
ko04970	Salivary secretion	27/733	95/7206	4.50459508214e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	22/733	74/7206	2.29514330574e-06
ko04010	MAPK signaling pathway	59/733	321/7206	4.52204691419e-06
ko03040	Spliceosome	1/733	145/7206	4.81132440471e-06
ko05203	Viral carcinogenesis	8/733	277/7206	5.85224955142e-06
ko05164	Influenza A	2/733	167/7206	6.0588269936e-06
ko05030	Cocaine addiction	21/733	73/7206	6.93782426601e-06
ko04740	Olfactory transduction	22/733	80/7206	9.42156604063e-06
ko04971	Gastric acid secretion	25/733	98/7206	1.01398496245e-05
ko04745	Phototransduction - fly	14/733	38/7206	1.05687753893e-05
ko04730	Long-term depression	21/733	78/7206	2.13722685348e-05
ko03010	Ribosome	1/733	129/7206	2.38349765539e-05
ko04260	Cardiac muscle contraction	24/733	98/7206	3.16642158595e-05
ko05162	Measles	1/733	120/7206	5.27896184173e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/733	79/7206	8.67186370287e-05
ko05169	Epstein-Barr virus infection	6/733	206/7206	9.67593663516e-05
ko05322	Systemic lupus erythematosus	3/733	151/7206	0.000176953730834
ko04070	Phosphatidylinositol signaling system	25/733	112/7206	0.000189083645517
ko04550	Signaling pathways regulating pluripotency of stem cells	4/733	165/7206	0.000210664581707
ko04514	Cell adhesion molecules (CAMs)	27/733	130/7206	0.000318073763714
ko04120	Ubiquitin mediated proteolysis	3/733	138/7206	0.000513046245726
ko03013	RNA transport	5/733	166/7206	0.00066506079367
ko04966	Collecting duct acid secretion	9/733	26/7206	0.000703439181226
ko05168	Herpes simplex infection	6/733	182/7206	0.000708986993732
ko04630	Jak-STAT signaling pathway	3/733	132/7206	0.000722455487988
ko04972	Pancreatic secretion	23/733	111/7206	0.00073689831851
ko04014	Ras signaling pathway	46/733	279/7206	0.000800902516687
ko04110	Cell cycle	4/733	145/7206	0.00120204166744
ko05215	Prostate cancer	2/733	111/7206	0.00123171864289
ko04626	Plant-pathogen interaction	7/733	18/7206	0.0012750970285
ko04750	Inflammatory mediator regulation of TRP channels	24/733	122/7206	0.0013021774871
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/733	14/7206	0.0015911596516
ko04072	Phospholipase D signaling pathway	34/733	197/7206	0.0017575228945
ko04621	NOD-like receptor signaling pathway	5/733	157/7206	0.00184872669271
ko04510	Focal adhesion	11/733	240/7206	0.00219103555033
ko05414	Dilated cardiomyopathy	22/733	112/7206	0.00229866657315
ko04350	TGF-beta signaling pathway	2/733	103/7206	0.00257431216847
ko04022	cGMP-PKG signaling pathway	36/733	216/7206	0.00272729233841
ko05166	HTLV-I infection	15/733	292/7206	0.00282613547412
ko04924	Renin secretion	18/733	86/7206	0.00317869113999
ko05205	Proteoglycans in cancer	14/733	271/7206	0.00391938224212
ko04610	Complement and coagulation cascades	1/733	79/7206	0.00408290428989
ko03008	Ribosome biogenesis in eukaryotes	1/733	79/7206	0.00408290428989
ko05161	Hepatitis B	7/733	173/7206	0.00470628992847
ko05110	Vibrio cholerae infection	14/733	63/7206	0.00480667912361
ko05410	Hypertrophic cardiomyopathy (HCM)	19/733	100/7206	0.00676615798777
ko05206	MicroRNAs in cancer	8/733	177/7206	0.00803052697445
ko04360	Axon guidance	36/733	233/7206	0.010750383998
ko05010	Alzheimer's disease	32/733	202/7206	0.0124520274151
ko04141	Protein processing in endoplasmic reticulum	9/733	184/7206	0.013096145894
ko05217	Basal cell carcinoma	1/733	68/7206	0.0132862489062
ko05034	Alcoholism	36/733	238/7206	0.0157730829092
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/733	59/7206	0.0158876203516
ko04064	NF-kappa B signaling pathway	3/733	96/7206	0.0164191135917
ko04978	Mineral absorption	9/733	40/7206	0.0168918361087
ko00680	Methane metabolism	8/733	34/7206	0.0182806550044
ko04915	Estrogen signaling pathway	22/733	131/7206	0.0183344874991
ko00562	Inositol phosphate metabolism	16/733	89/7206	0.0207145765361
ko05130	Pathogenic Escherichia coli infection	2/733	77/7206	0.0216486424581
ko04964	Proximal tubule bicarbonate reclamation	7/733	29/7206	0.0232754685883
ko04540	Gap junction	21/733	128/7206	0.0257532911134
ko05202	Transcriptional misregulation in cancer	10/733	188/7206	0.026738907814
ko05200	Pathways in cancer	36/733	492/7206	0.0302397086881
ko04214	Apoptosis - fly	2/733	72/7206	0.0306289041172
ko05140	Leishmaniasis	2/733	75/7206	0.0317429893715
ko04960	Aldosterone-regulated sodium reabsorption	9/733	41/7206	0.0318939740058
ko05222	Small cell lung cancer	3/733	89/7206	0.0321891659039
ko04114	Oocyte meiosis	22/733	139/7206	0.0327381559755
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/733	182/7206	0.0339741350188
ko04150	mTOR signaling pathway	10/733	184/7206	0.0344992997188
ko00480	Glutathione metabolism	1/733	55/7206	0.0402291559503
ko05321	Inflammatory bowel disease (IBD)	1/733	56/7206	0.0412941633757
ko05212	Pancreatic cancer	3/733	83/7206	0.0438789817751
ko05220	Chronic myeloid leukemia	3/733	85/7206	0.0446008880982