ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 27/190 191/7206 4.67969329517e-13 ko04621 NOD-like receptor signaling pathway 18/190 157/7206 1.30999779011e-07 ko05164 Influenza A 17/190 167/7206 1.62884713602e-06 ko04380 Osteoclast differentiation 15/190 134/7206 2.07925781887e-06 ko04657 IL-17 signaling pathway 11/190 87/7206 1.56365590295e-05 ko04217 Necroptosis 16/190 178/7206 1.66219270688e-05 ko04622 RIG-I-like receptor signaling pathway 9/190 62/7206 3.09116834705e-05 ko04064 NF-kappa B signaling pathway 11/190 96/7206 4.00487207488e-05 ko05160 Hepatitis C 14/190 153/7206 4.68299848072e-05 ko04668 TNF signaling pathway 12/190 120/7206 6.97677145156e-05 ko00643 Styrene degradation 3/190 4/7206 7.0793228344e-05 ko04623 Cytosolic DNA-sensing pathway 7/190 41/7206 8.34126921557e-05 ko00350 Tyrosine metabolism 6/190 33/7206 0.000189908002343 ko05323 Rheumatoid arthritis 9/190 89/7206 0.000525050476565 ko05145 Toxoplasmosis 10/190 126/7206 0.00174296285656 ko00950 Isoquinoline alkaloid biosynthesis 3/190 10/7206 0.00188841398506 ko00590 Arachidonic acid metabolism 6/190 52/7206 0.00230534429338 ko04062 Chemokine signaling pathway 13/190 201/7206 0.0024403684826 ko04672 Intestinal immune network for IgA production 5/190 37/7206 0.0026547150143 ko04210 Apoptosis 12/190 180/7206 0.00277357761142 ko04658 Th1 and Th2 cell differentiation 8/190 96/7206 0.00368789400511 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/190 4/7206 0.00400691521437 ko04620 Toll-like receptor signaling pathway 8/190 100/7206 0.00473437560615 ko05161 Hepatitis B 11/190 173/7206 0.00588534865274 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/190 5/7206 0.00656249788679 ko05142 Chagas disease (American trypanosomiasis) 9/190 130/7206 0.00722438961172 ko05168 Herpes simplex infection 11/190 182/7206 0.00852032225828 ko00360 Phenylalanine metabolism 3/190 17/7206 0.00934111566596 ko04611 Platelet activation 10/190 163/7206 0.0107908923536 ko05146 Amoebiasis 7/190 99/7206 0.0153552428431 ko04660 T cell receptor signaling pathway 8/190 124/7206 0.0164518678203 ko04670 Leukocyte transendothelial migration 9/190 151/7206 0.0181045022793 ko04976 Bile secretion 6/190 80/7206 0.0185893890767 ko05131 Shigellosis 6/190 82/7206 0.0207530760519 ko00140 Steroid hormone biosynthesis 4/190 41/7206 0.0221712169457 ko04630 Jak-STAT signaling pathway 8/190 132/7206 0.0230686079304 ko05418 Fluid shear stress and atherosclerosis 10/190 173/7206 0.0251751483518 ko04924 Renin secretion 6/190 86/7206 0.0255802426883 ko00401 Novobiocin biosynthesis 1/190 1/7206 0.0263669164585 ko05133 Pertussis 6/190 87/7206 0.0268945744397 ko04662 B cell receptor signaling pathway 6/190 88/7206 0.0282530063421 ko05152 Tuberculosis 10/190 187/7206 0.0321209538638 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/190 92/7206 0.0341374279819 ko04215 Apoptosis - multiple species 4/190 47/7206 0.0345993740124 ko04624 Toll and Imd signaling pathway 4/190 49/7206 0.0394814975706 ko00512 Mucin type O-glycan biosynthesis 3/190 29/7206 0.0398802047151 ko04974 Protein digestion and absorption 6/190 96/7206 0.0407633357689 ko04750 Inflammatory mediator regulation of TRP channels 7/190 122/7206 0.0419340828269 ko05132 Salmonella infection 6/190 98/7206 0.0443614749556 ko05134 Legionellosis 5/190 74/7206 0.0451160759266 ko00564 Glycerophospholipid metabolism 6/190 99/7206 0.0462328447694