ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04728	Dopaminergic synapse	37/338	185/7206	2.25018244505e-14
ko04721	Synaptic vesicle cycle	22/338	80/7206	6.70158360704e-12
ko04724	Glutamatergic synapse	29/338	152/7206	5.72196308658e-11
ko04713	Circadian entrainment	24/338	136/7206	1.40000024535e-08
ko04911	Insulin secretion	22/338	117/7206	1.71649075835e-08
ko04727	GABAergic synapse	21/338	110/7206	2.76967218442e-08
ko04725	Cholinergic synapse	25/338	160/7206	8.63717337851e-08
ko05033	Nicotine addiction	13/338	56/7206	1.27966464068e-06
ko04726	Serotonergic synapse	21/338	137/7206	1.32777006328e-06
ko04723	Retrograde endocannabinoid signaling	24/338	175/7206	1.83161860097e-06
ko05031	Amphetamine addiction	16/338	91/7206	4.03174560678e-06
ko04261	Adrenergic signaling in cardiomyocytes	25/338	205/7206	9.57396050116e-06
ko05032	Morphine addiction	17/338	110/7206	1.23007851027e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	13/338	74/7206	3.29370453645e-05
ko04720	Long-term potentiation	15/338	99/7206	5.08219542147e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/338	59/7206	7.57983525304e-05
ko05030	Cocaine addiction	12/338	73/7206	0.000129143702471
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/338	92/7206	0.000327491514058
ko04360	Axon guidance	24/338	233/7206	0.000368002605706
ko04024	cAMP signaling pathway	27/338	279/7206	0.000388947498836
ko04391	Hippo signaling pathway - fly	12/338	90/7206	0.00093975848623
ko04966	Collecting duct acid secretion	6/338	26/7206	0.00105536397371
ko04010	MAPK signaling pathway	28/338	321/7206	0.00159531082959
ko04745	Phototransduction - fly	7/338	38/7206	0.00168243178471
ko04145	Phagosome	17/338	162/7206	0.00185922031749
ko04964	Proximal tubule bicarbonate reclamation	6/338	29/7206	0.0019334105693
ko04014	Ras signaling pathway	25/338	279/7206	0.0020107615627
ko04970	Salivary secretion	11/338	95/7206	0.00468938655823
ko04972	Pancreatic secretion	12/338	111/7206	0.00561258705952
ko04971	Gastric acid secretion	11/338	98/7206	0.00594060054668
ko05100	Bacterial invasion of epithelial cells	11/338	99/7206	0.00641148500029
ko04626	Plant-pathogen interaction	4/338	18/7206	0.00862430867128
ko05034	Alcoholism	20/338	238/7206	0.0113550384714
ko04960	Aldosterone-regulated sodium reabsorption	6/338	41/7206	0.0114144746425
ko04071	Sphingolipid signaling pathway	15/338	162/7206	0.0123415675576
ko04930	Type II diabetes mellitus	7/338	54/7206	0.0124466937953
ko04973	Carbohydrate digestion and absorption	6/338	42/7206	0.0128065088198
ko05167	Kaposi's sarcoma-associated herpesvirus infection	17/338	191/7206	0.013307986734
ko04015	Rap1 signaling pathway	22/338	278/7206	0.0136639708311
ko04940	Type I diabetes mellitus	5/338	32/7206	0.0156241169608
ko04922	Glucagon signaling pathway	12/338	128/7206	0.0186615558408
ko04924	Renin secretion	9/338	86/7206	0.0188695301016
ko04022	cGMP-PKG signaling pathway	18/338	216/7206	0.020137882916
ko03013	RNA transport	2/338	166/7206	0.0247536356176
ko04744	Phototransduction	5/338	36/7206	0.0251287883235
ko04151	PI3K-Akt signaling pathway	28/338	390/7206	0.0255091997031
ko05130	Pathogenic Escherichia coli infection	8/338	77/7206	0.0271296871605
ko04370	VEGF signaling pathway	8/338	77/7206	0.0271296871605
ko05110	Vibrio cholerae infection	7/338	63/7206	0.0272290959015
ko04750	Inflammatory mediator regulation of TRP channels	11/338	122/7206	0.0303288977804
ko02024	Quorum sensing	3/338	15/7206	0.0305784718978
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/338	15/7206	0.0305784718978
ko04925	Aldosterone synthesis and secretion	10/338	105/7206	0.0311886580411
ko01200	Carbon metabolism	1/338	128/7206	0.0316157584242
ko05152	Tuberculosis	15/338	187/7206	0.0353096489007
ko04060	Cytokine-cytokine receptor interaction	3/338	191/7206	0.0358141633672
ko04978	Mineral absorption	5/338	40/7206	0.0377135514567
ko04114	Oocyte meiosis	12/338	139/7206	0.0390524527822
ko04070	Phosphatidylinositol signaling system	10/338	112/7206	0.0412685783899
ko00512	Mucin type O-glycan biosynthesis	4/338	29/7206	0.0447456836218
ko05162	Measles	1/338	120/7206	0.0457247936099
ko04921	Oxytocin signaling pathway	16/338	209/7206	0.0459358808565
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/338	1/7206	0.0469053566475
ko04371	Apelin signaling pathway	14/338	177/7206	0.0471236843133
ko04260	Cardiac muscle contraction	9/338	98/7206	0.0485050256461
ko05168	Herpes simplex infection	3/338	182/7206	0.0490053774036