ko pathway ratio_in_study ratio_in_pop p_value ko00190 Oxidative phosphorylation 29/256 127/7206 3.19584628224e-16 ko05012 Parkinson's disease 27/256 155/7206 3.79364514949e-12 ko05010 Alzheimer's disease 28/256 202/7206 4.10290627838e-10 ko04932 Non-alcoholic fatty liver disease (NAFLD) 25/256 182/7206 4.57745985085e-09 ko05016 Huntington's disease 27/256 215/7206 7.86044400787e-09 ko00071 Fatty acid degradation 11/256 45/7206 3.19014928725e-07 ko01200 Carbon metabolism 17/256 128/7206 2.40535612849e-06 ko00620 Pyruvate metabolism 10/256 46/7206 3.53923771352e-06 ko04137 Mitophagy - animal 13/256 82/7206 5.28919908345e-06 ko00640 Propanoate metabolism 8/256 34/7206 1.85000364293e-05 ko00362 Benzoate degradation 4/256 6/7206 2.20680179879e-05 ko00120 Primary bile acid biosynthesis 6/256 20/7206 4.82920267988e-05 ko04146 Peroxisome 12/256 89/7206 6.4891105384e-05 ko04260 Cardiac muscle contraction 12/256 98/7206 0.0001671901873 ko00710 Carbon fixation in photosynthetic organisms 6/256 27/7206 0.00029910290847 ko00380 Tryptophan metabolism 8/256 50/7206 0.000334321420087 ko04138 Autophagy - yeast 10/256 81/7206 0.000546014727373 ko00280 Valine, leucine and isoleucine degradation 8/256 54/7206 0.000573125504838 ko04136 Autophagy - other 6/256 31/7206 0.000660307226823 ko03320 PPAR signaling pathway 9/256 69/7206 0.000686783149244 ko04080 Neuroactive ligand-receptor interaction 4/256 423/7206 0.00101112646869 ko00310 Lysine degradation 9/256 73/7206 0.00103980511011 ko01212 Fatty acid metabolism 8/256 60/7206 0.00117297223419 ko00020 Citrate cycle (TCA cycle) 6/256 35/7206 0.0012923622646 ko00330 Arginine and proline metabolism 8/256 61/7206 0.00130939521224 ko00220 Arginine biosynthesis 5/256 24/7206 0.00132791655833 ko04922 Glucagon signaling pathway 12/256 128/7206 0.00190196713451 ko01230 Biosynthesis of amino acids 9/256 85/7206 0.0030475990311 ko04710 Circadian rhythm 6/256 43/7206 0.00382960364446 ko00950 Isoquinoline alkaloid biosynthesis 3/256 10/7206 0.00441730283574 ko00010 Glycolysis / Gluconeogenesis 8/256 74/7206 0.00450988337434 ko00270 Cysteine and methionine metabolism 6/256 47/7206 0.00599409847356 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/256 4/7206 0.00719404533958 ko04975 Fat digestion and absorption 5/256 35/7206 0.00738026157712 ko00564 Glycerophospholipid metabolism 9/256 99/7206 0.0083432795393 ko04068 FoxO signaling pathway 13/256 167/7206 0.00855332807883 ko04711 Circadian rhythm - fly 3/256 13/7206 0.00972856691363 ko00630 Glyoxylate and dicarboxylate metabolism 5/256 38/7206 0.0104694713297 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/256 5/7206 0.0117098857359 ko04060 Cytokine-cytokine receptor interaction 1/256 191/7206 0.0153900575683 ko05200 Pathways in cancer 8/256 492/7206 0.0156161306558 ko04140 Autophagy - animal 12/256 164/7206 0.0161142648063 ko02020 Two-component system 3/256 17/7206 0.0208335874357 ko00360 Phenylalanine metabolism 3/256 17/7206 0.0208335874357 ko00561 Glycerolipid metabolism 6/256 63/7206 0.023739486989 ko04626 Plant-pathogen interaction 3/256 18/7206 0.0243580337149 ko04270 Vascular smooth muscle contraction 11/256 154/7206 0.0245140954654 ko00592 alpha-Linolenic acid metabolism 3/256 19/7206 0.0281834774143 ko00350 Tyrosine metabolism 4/256 33/7206 0.0283505045874 ko03013 RNA transport 1/256 166/7206 0.0315913814412 ko01210 2-Oxocarboxylic acid metabolism 3/256 20/7206 0.0323084653881 ko00410 beta-Alanine metabolism 4/256 35/7206 0.0343440757364 ko04139 Mitophagy - yeast 4/256 37/7206 0.0410190930707 ko04066 HIF-1 signaling pathway 9/256 123/7206 0.041822993574 ko05322 Systemic lupus erythematosus 1/256 151/7206 0.0451122063575 ko00072 Synthesis and degradation of ketone bodies 2/256 10/7206 0.0468686509052