ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	107/632	423/7206	9.61813567825e-26
ko04724	Glutamatergic synapse	60/632	152/7206	1.74047021618e-25
ko05033	Nicotine addiction	36/632	56/7206	5.10228806814e-25
ko04728	Dopaminergic synapse	60/632	185/7206	2.33392065287e-20
ko04727	GABAergic synapse	40/632	110/7206	7.40550064494e-16
ko05032	Morphine addiction	40/632	110/7206	7.40550064494e-16
ko04721	Synaptic vesicle cycle	33/632	80/7206	3.6166167778e-15
ko04713	Circadian entrainment	44/632	136/7206	3.72571757079e-15
ko04723	Retrograde endocannabinoid signaling	50/632	175/7206	1.29986825223e-14
ko04024	cAMP signaling pathway	64/632	279/7206	2.17680790114e-13
ko04725	Cholinergic synapse	42/632	160/7206	3.89412365058e-11
ko04726	Serotonergic synapse	37/632	137/7206	2.42679275423e-10
ko04911	Insulin secretion	33/632	117/7206	6.79866424873e-10
ko05030	Cocaine addiction	25/632	73/7206	9.6370222802e-10
ko05031	Amphetamine addiction	28/632	91/7206	1.5630316095e-09
ko04261	Adrenergic signaling in cardiomyocytes	45/632	205/7206	4.29322825277e-09
ko04020	Calcium signaling pathway	53/632	265/7206	6.23473258457e-09
ko04720	Long-term potentiation	27/632	99/7206	5.41653695216e-08
ko04921	Oxytocin signaling pathway	42/632	209/7206	2.79430569543e-07
ko04010	MAPK signaling pathway	56/632	321/7206	4.51442302338e-07
ko04514	Cell adhesion molecules (CAMs)	30/632	130/7206	5.61045108832e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	21/632	74/7206	8.05408957946e-07
ko04730	Long-term depression	21/632	78/7206	2.07677429401e-06
ko04742	Taste transduction	18/632	61/7206	2.658567211e-06
ko04360	Axon guidance	42/632	233/7206	4.9975857027e-06
ko04744	Phototransduction	13/632	36/7206	5.562491743e-06
ko04970	Salivary secretion	22/632	95/7206	1.71540619088e-05
ko03040	Spliceosome	1/632	145/7206	3.96616404509e-05
ko04060	Cytokine-cytokine receptor interaction	3/632	191/7206	4.31557105749e-05
ko04972	Pancreatic secretion	23/632	111/7206	0.000107792464146
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/632	79/7206	0.000123895480743
ko05203	Viral carcinogenesis	9/632	277/7206	0.00031415694488
ko04022	cGMP-PKG signaling pathway	35/632	216/7206	0.000329051534943
ko04260	Cardiac muscle contraction	20/632	98/7206	0.000380725853329
ko03013	RNA transport	3/632	166/7206	0.000400449207597
ko04120	Ubiquitin mediated proteolysis	2/632	138/7206	0.000635593535052
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/632	14/7206	0.000722365181749
ko05164	Influenza A	4/632	167/7206	0.00127327972759
ko04925	Aldosterone synthesis and secretion	19/632	105/7206	0.00241636854691
ko04621	NOD-like receptor signaling pathway	4/632	157/7206	0.00248803539538
ko04915	Estrogen signaling pathway	22/632	131/7206	0.00264242365246
ko04071	Sphingolipid signaling pathway	26/632	162/7206	0.00272071906394
ko04072	Phospholipase D signaling pathway	30/632	197/7206	0.00293227600978
ko04971	Gastric acid secretion	18/632	98/7206	0.00313729712707
ko04540	Gap junction	21/632	128/7206	0.0042003293251
ko04146	Peroxisome	1/632	89/7206	0.00422467085411
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/632	59/7206	0.00448044139133
ko05168	Herpes simplex infection	6/632	182/7206	0.00500494078045
ko05322	Systemic lupus erythematosus	4/632	151/7206	0.00504648213812
ko00240	Pyrimidine metabolism	2/632	110/7206	0.00563522310409
ko03018	RNA degradation	1/632	84/7206	0.00619793849642
ko04930	Type II diabetes mellitus	11/632	54/7206	0.00631037988841
ko01200	Carbon metabolism	3/632	128/7206	0.00646339689215
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/632	15/7206	0.00728837071427
ko05205	Proteoglycans in cancer	12/632	271/7206	0.0082016169446
ko05162	Measles	3/632	120/7206	0.00877328593454
ko04137	Mitophagy - animal	1/632	82/7206	0.00922460217074
ko05414	Dilated cardiomyopathy	18/632	112/7206	0.0105332610361
ko04924	Renin secretion	15/632	86/7206	0.0105806014369
ko00512	Mucin type O-glycan biosynthesis	7/632	29/7206	0.0108966998634
ko04964	Proximal tubule bicarbonate reclamation	7/632	29/7206	0.0108966998634
ko04141	Protein processing in endoplasmic reticulum	7/632	184/7206	0.0117744941066
ko05034	Alcoholism	32/632	238/7206	0.0138530950336
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/632	182/7206	0.0159303651129
ko04014	Ras signaling pathway	36/632	279/7206	0.0171254945297
ko05410	Hypertrophic cardiomyopathy (HCM)	16/632	100/7206	0.0184897629793
ko00310	Lysine degradation	1/632	73/7206	0.0197115760303
ko04966	Collecting duct acid secretion	6/632	26/7206	0.0223663719763
ko05169	Epstein-Barr virus infection	9/632	206/7206	0.0234690353641
ko04070	Phosphatidylinositol signaling system	17/632	112/7206	0.0263481797151
ko04973	Carbohydrate digestion and absorption	8/632	42/7206	0.0273315611388
ko04391	Hippo signaling pathway - fly	14/632	90/7206	0.0358468695601
ko04144	Endocytosis	41/632	342/7206	0.0389915238142
ko04640	Hematopoietic cell lineage	1/632	64/7206	0.0418260279547
ko04630	Jak-STAT signaling pathway	5/632	132/7206	0.0419616117766
ko04217	Necroptosis	8/632	178/7206	0.0429428385397
ko04064	NF-kappa B signaling pathway	3/632	96/7206	0.0453076702811