ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	69/559	145/7206	5.0504683446e-39
ko03013	RNA transport	60/559	166/7206	5.51754217079e-26
ko03440	Homologous recombination	29/559	41/7206	1.03957602081e-23
ko04110	Cell cycle	50/559	145/7206	9.76262936778e-21
ko03460	Fanconi anemia pathway	28/559	51/7206	1.54795349879e-18
ko03030	DNA replication	23/559	38/7206	9.67625184347e-17
ko04111	Cell cycle - yeast	35/559	90/7206	9.8677516584e-17
ko03008	Ribosome biogenesis in eukaryotes	32/559	79/7206	5.20436676907e-16
ko05322	Systemic lupus erythematosus	43/559	151/7206	1.52573729321e-14
ko00240	Pyrimidine metabolism	34/559	110/7206	7.14284244858e-13
ko04113	Meiosis - yeast	25/559	70/7206	2.4224250806e-11
ko03430	Mismatch repair	13/559	22/7206	8.34303649632e-10
ko03420	Nucleotide excision repair	18/559	46/7206	2.85622321341e-09
ko04144	Endocytosis	3/559	342/7206	4.89855521952e-09
ko05034	Alcoholism	44/559	238/7206	3.91452382043e-08
ko03018	RNA degradation	23/559	84/7206	5.21739615952e-08
ko04020	Calcium signaling pathway	2/559	265/7206	2.24175461662e-07
ko03015	mRNA surveillance pathway	23/559	93/7206	3.96324622119e-07
ko03410	Base excision repair	14/559	38/7206	4.10430504501e-07
ko03020	RNA polymerase	12/559	29/7206	6.43211799265e-07
ko05203	Viral carcinogenesis	45/559	277/7206	1.54043374477e-06
ko04024	cAMP signaling pathway	4/559	279/7206	3.2668833071e-06
ko04151	PI3K-Akt signaling pathway	9/559	390/7206	3.60782306139e-06
ko04510	Focal adhesion	4/559	240/7206	4.1189572797e-05
ko04022	cGMP-PKG signaling pathway	3/559	216/7206	4.60268250131e-05
ko04621	NOD-like receptor signaling pathway	1/559	157/7206	6.25559296181e-05
ko04010	MAPK signaling pathway	8/559	321/7206	6.58977401264e-05
ko05152	Tuberculosis	2/559	187/7206	7.15438129329e-05
ko04724	Glutamatergic synapse	1/559	152/7206	9.25550836725e-05
ko04270	Vascular smooth muscle contraction	1/559	154/7206	9.38984552444e-05
ko05012	Parkinson's disease	1/559	155/7206	9.58257687747e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/559	182/7206	0.000104664849541
ko04723	Retrograde endocannabinoid signaling	2/559	175/7206	0.000147400196992
ko04810	Regulation of actin cytoskeleton	6/559	264/7206	0.000225446964571
ko04014	Ras signaling pathway	7/559	279/7206	0.000228792418792
ko04015	Rap1 signaling pathway	7/559	278/7206	0.000327575601214
ko04921	Oxytocin signaling pathway	4/559	209/7206	0.000338550636048
ko03022	Basal transcription factors	11/559	44/7206	0.000400519888754
ko04728	Dopaminergic synapse	3/559	185/7206	0.000404370091243
ko04713	Circadian entrainment	1/559	136/7206	0.000474709435811
ko04261	Adrenergic signaling in cardiomyocytes	4/559	205/7206	0.000480110546223
ko04114	Oocyte meiosis	23/559	139/7206	0.000543987889133
ko00230	Purine metabolism	29/559	194/7206	0.000547635133199
ko03450	Non-homologous end-joining	6/559	15/7206	0.000578465729464
ko00190	Oxidative phosphorylation	1/559	127/7206	0.000647815788207
ko04062	Chemokine signaling pathway	4/559	201/7206	0.000685735388811
ko05010	Alzheimer's disease	4/559	202/7206	0.000697227303158
ko04072	Phospholipase D signaling pathway	4/559	197/7206	0.000985644349482
ko04218	Cellular senescence	26/559	177/7206	0.00146455120184
ko04668	TNF signaling pathway	1/559	120/7206	0.00147791877972
ko04530	Tight junction	6/559	228/7206	0.0014989169304
ko05166	HTLV-I infection	38/559	292/7206	0.00157929301063
ko04611	Platelet activation	3/559	163/7206	0.00164549382358
ko04725	Cholinergic synapse	3/559	160/7206	0.00238032888175
ko04152	AMPK signaling pathway	3/559	161/7206	0.00242470870811
ko04914	Progesterone-mediated oocyte maturation	17/559	104/7206	0.00269533691855
ko04630	Jak-STAT signaling pathway	2/559	132/7206	0.00277364812849
ko04727	GABAergic synapse	1/559	110/7206	0.00319993546825
ko05032	Morphine addiction	1/559	110/7206	0.00319993546825
ko04142	Lysosome	3/559	151/7206	0.00328433548452
ko05418	Fluid shear stress and atherosclerosis	4/559	173/7206	0.00361775158879
ko05145	Toxoplasmosis	2/559	126/7206	0.0039736411838
ko01200	Carbon metabolism	2/559	128/7206	0.00400371716676
ko04514	Cell adhesion molecules (CAMs)	2/559	130/7206	0.00413101398513
ko04120	Ubiquitin mediated proteolysis	20/559	138/7206	0.00569906738244
ko04970	Salivary secretion	1/559	95/7206	0.00643395132942
ko04260	Cardiac muscle contraction	1/559	98/7206	0.00656905744569
ko05205	Proteoglycans in cancer	10/559	271/7206	0.00754730943272
ko04360	Axon guidance	8/559	233/7206	0.00862424802528
ko04726	Serotonergic synapse	3/559	137/7206	0.00910908154732
ko05031	Amphetamine addiction	1/559	91/7206	0.00939239134642
ko04070	Phosphatidylinositol signaling system	2/559	112/7206	0.0115899714218
ko05142	Chagas disease (American trypanosomiasis)	3/559	130/7206	0.0126544028036
ko04915	Estrogen signaling pathway	3/559	131/7206	0.0126700072883
ko04380	Osteoclast differentiation	3/559	134/7206	0.0130624194249
ko01230	Biosynthesis of amino acids	1/559	85/7206	0.0136580539286
ko04924	Renin secretion	1/559	86/7206	0.0136947504128
ko04918	Thyroid hormone synthesis	1/559	86/7206	0.0136947504128
ko04920	Adipocytokine signaling pathway	1/559	89/7206	0.0143569340616
ko04925	Aldosterone synthesis and secretion	2/559	105/7206	0.0163397804975
ko05202	Transcriptional misregulation in cancer	24/559	188/7206	0.0176103833157
ko04721	Synaptic vesicle cycle	1/559	80/7206	0.0198573276387
ko04976	Bile secretion	1/559	80/7206	0.0198573276387
ko04371	Apelin signaling pathway	6/559	177/7206	0.0226067476367
ko04620	Toll-like receptor signaling pathway	2/559	100/7206	0.0231132226504
ko04071	Sphingolipid signaling pathway	5/559	162/7206	0.0243088117684
ko04750	Inflammatory mediator regulation of TRP channels	3/559	122/7206	0.0247304705069
ko04666	Fc gamma R-mediated phagocytosis	3/559	122/7206	0.0247304705069
ko05140	Leishmaniasis	1/559	75/7206	0.0288255550386
ko00010	Glycolysis / Gluconeogenesis	1/559	74/7206	0.0288442090867
ko04612	Antigen processing and presentation	1/559	77/7206	0.0293201311846
ko04923	Regulation of lipolysis in adipocytes	1/559	77/7206	0.0293201311846
ko04512	ECM-receptor interaction	1/559	79/7206	0.0305241924736
ko00450	Selenocompound metabolism	4/559	16/7206	0.0307751644997
ko04971	Gastric acid secretion	2/559	98/7206	0.0335674334709
ko04931	Insulin resistance	4/559	137/7206	0.0339721336693
ko05168	Herpes simplex infection	22/559	182/7206	0.0342852483977
ko05030	Cocaine addiction	1/559	73/7206	0.0433590304143
ko04115	p53 signaling pathway	11/559	74/7206	0.0443704620292
ko04922	Glucagon signaling pathway	4/559	128/7206	0.0449266119472
ko04146	Peroxisome	2/559	89/7206	0.0457869345231
ko05323	Rheumatoid arthritis	2/559	89/7206	0.0457869345231
ko00562	Inositol phosphate metabolism	2/559	89/7206	0.0457869345231
ko05169	Epstein-Barr virus infection	24/559	206/7206	0.0458453974674
ko04972	Pancreatic secretion	3/559	111/7206	0.046849285736
ko04141	Protein processing in endoplasmic reticulum	7/559	184/7206	0.0487850774745