ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 23/349 120/7206 1.00902997126e-08 ko04380 Osteoclast differentiation 24/349 134/7206 1.9344877317e-08 ko04621 NOD-like receptor signaling pathway 26/349 157/7206 2.65584186368e-08 ko04060 Cytokine-cytokine receptor interaction 29/349 191/7206 3.0582920014e-08 ko04512 ECM-receptor interaction 17/349 79/7206 1.53555032983e-07 ko04974 Protein digestion and absorption 17/349 96/7206 2.81113663798e-06 ko00643 Styrene degradation 4/349 4/7206 5.41246227873e-06 ko04657 IL-17 signaling pathway 15/349 87/7206 1.5229233754e-05 ko04510 Focal adhesion 28/349 240/7206 1.74801007065e-05 ko05323 Rheumatoid arthritis 15/349 89/7206 2.02105482362e-05 ko05164 Influenza A 21/349 167/7206 5.06167782192e-05 ko04064 NF-kappa B signaling pathway 15/349 96/7206 5.08413398291e-05 ko04210 Apoptosis 22/349 180/7206 5.2104025501e-05 ko04611 Platelet activation 20/349 163/7206 0.000108048435005 ko04623 Cytosolic DNA-sensing pathway 9/349 41/7206 0.000116755457105 ko04630 Jak-STAT signaling pathway 17/349 132/7206 0.000196245592594 ko05133 Pertussis 13/349 87/7206 0.000254383975853 ko05168 Herpes simplex infection 21/349 182/7206 0.000282630162787 ko04620 Toll-like receptor signaling pathway 14/349 100/7206 0.000299028024789 ko05145 Toxoplasmosis 16/349 126/7206 0.000354452485286 ko05132 Salmonella infection 13/349 98/7206 0.000825672095449 ko00350 Tyrosine metabolism 7/349 33/7206 0.00084306399701 ko05160 Hepatitis C 17/349 153/7206 0.00157462196203 ko04672 Intestinal immune network for IgA production 7/349 37/7206 0.00171968855189 ko00660 C5-Branched dibasic acid metabolism 2/349 2/7206 0.00233924886793 ko05146 Amoebiasis 12/349 99/7206 0.00283474667903 ko05140 Leishmaniasis 10/349 75/7206 0.00311026144071 ko00140 Steroid hormone biosynthesis 7/349 41/7206 0.00318010029123 ko04640 Hematopoietic cell lineage 9/349 64/7206 0.00343879215082 ko05120 Epithelial cell signaling in Helicobacter pylori infection 11/349 92/7206 0.00465993292475 ko05034 Alcoholism 3/349 238/7206 0.00506708123231 ko04810 Regulation of actin cytoskeleton 23/349 264/7206 0.0052611208618 ko05144 Malaria 7/349 45/7206 0.00543881334746 ko05161 Hepatitis B 17/349 173/7206 0.0058312841086 ko05131 Shigellosis 10/349 82/7206 0.00595244561529 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/349 135/7206 0.00673066373206 ko05162 Measles 13/349 120/7206 0.00762158555633 ko04660 T cell receptor signaling pathway 13/349 124/7206 0.00880835989583 ko04917 Prolactin signaling pathway 10/349 87/7206 0.00899704015601 ko05134 Legionellosis 9/349 74/7206 0.00904003600197 ko04115 p53 signaling pathway 9/349 74/7206 0.00904003600197 ko05322 Systemic lupus erythematosus 1/349 151/7206 0.0107816741285 ko04141 Protein processing in endoplasmic reticulum 2/349 184/7206 0.0130803849936 ko04610 Complement and coagulation cascades 9/349 79/7206 0.01363774212 ko04114 Oocyte meiosis 1/349 139/7206 0.0149333661071 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/349 191/7206 0.0150184621548 ko05321 Inflammatory bowel disease (IBD) 7/349 56/7206 0.0176745342342 ko04932 Non-alcoholic fatty liver disease (NAFLD) 16/349 182/7206 0.0207786188672 ko03010 Ribosome 1/349 129/7206 0.0213941904174 ko04931 Insulin resistance 13/349 137/7206 0.0235446573872 ko04658 Th1 and Th2 cell differentiation 10/349 96/7206 0.0255595092725 ko05219 Bladder cancer 6/349 48/7206 0.0272445955582 ko05150 Staphylococcus aureus infection 5/349 36/7206 0.0283783259752 ko04622 RIG-I-like receptor signaling pathway 7/349 62/7206 0.0293349050194 ko00362 Benzoate degradation 2/349 6/7206 0.0308190850792 ko05016 Huntington's disease 4/349 215/7206 0.0349994450544 ko04728 Dopaminergic synapse 3/349 185/7206 0.0357484284453 ko04662 B cell receptor signaling pathway 9/349 88/7206 0.0382894385057 ko05222 Small cell lung cancer 9/349 89/7206 0.0394241198101 ko00360 Phenylalanine metabolism 3/349 17/7206 0.0462270088217 ko04080 Neuroactive ligand-receptor interaction 12/349 423/7206 0.0468072767711 ko04916 Melanogenesis 2/349 142/7206 0.0483617766969 ko00401 Novobiocin biosynthesis 1/349 1/7206 0.0484318623371