ko pathway ratio_in_study ratio_in_pop p_value ko04728 Dopaminergic synapse 22/231 185/7206 8.88420531083e-08 ko04925 Aldosterone synthesis and secretion 16/231 105/7206 1.82962551897e-07 ko04745 Phototransduction - fly 10/231 38/7206 2.0274841662e-07 ko04070 Phosphatidylinositol signaling system 16/231 112/7206 4.55266224098e-07 ko04720 Long-term potentiation 15/231 99/7206 4.83362764304e-07 ko04921 Oxytocin signaling pathway 22/231 209/7206 7.65162593835e-07 ko05031 Amphetamine addiction 14/231 91/7206 9.72040107533e-07 ko04713 Circadian entrainment 16/231 136/7206 6.29922098023e-06 ko04020 Calcium signaling pathway 22/231 265/7206 3.67036814634e-05 ko04725 Cholinergic synapse 16/231 160/7206 4.92886952594e-05 ko04922 Glucagon signaling pathway 14/231 128/7206 5.51400445769e-05 ko04911 Insulin secretion 13/231 117/7206 8.65811584597e-05 ko00562 Inositol phosphate metabolism 11/231 89/7206 0.000116569218772 ko04626 Plant-pathogen interaction 5/231 18/7206 0.000197300257675 ko04740 Olfactory transduction 10/231 80/7206 0.000216778045341 ko04724 Glutamatergic synapse 14/231 152/7206 0.000348428561504 ko00680 Methane metabolism 6/231 34/7206 0.00064370567248 ko05214 Glioma 9/231 79/7206 0.000892004452392 ko05230 Central carbon metabolism in cancer 9/231 81/7206 0.00106973607106 ko04971 Gastric acid secretion 10/231 98/7206 0.00111490337599 ko04114 Oocyte meiosis 12/231 139/7206 0.00161519401128 ko04912 GnRH signaling pathway 11/231 122/7206 0.00177215431157 ko04730 Long-term depression 8/231 78/7206 0.00335048475138 ko04371 Apelin signaling pathway 13/231 177/7206 0.00438570000318 ko04722 Neurotrophin signaling pathway 12/231 160/7206 0.00517425039715 ko04750 Inflammatory mediator regulation of TRP channels 10/231 122/7206 0.00562827502996 ko04071 Sphingolipid signaling pathway 12/231 162/7206 0.00570907958212 ko04261 Adrenergic signaling in cardiomyocytes 14/231 205/7206 0.00716274397594 ko04012 ErbB signaling pathway 9/231 109/7206 0.00807423305301 ko05032 Morphine addiction 9/231 110/7206 0.00855557446805 ko00010 Glycolysis / Gluconeogenesis 7/231 74/7206 0.00922484653315 ko00051 Fructose and mannose metabolism 5/231 42/7206 0.010486748392 ko04970 Salivary secretion 8/231 95/7206 0.0109310724445 ko04013 MAPK signaling pathway - fly 9/231 115/7206 0.0112967390642 ko04726 Serotonergic synapse 10/231 137/7206 0.0123664866469 ko04721 Synaptic vesicle cycle 7/231 80/7206 0.0138655374167 ko05010 Alzheimer's disease 13/231 202/7206 0.0140729598752 ko04666 Fc gamma R-mediated phagocytosis 9/231 122/7206 0.0161778072351 ko04066 HIF-1 signaling pathway 9/231 123/7206 0.016984564754 ko00030 Pentose phosphate pathway 4/231 32/7206 0.0182933382058 ko04152 AMPK signaling pathway 11/231 161/7206 0.0191304923554 ko04924 Renin secretion 7/231 86/7206 0.0199798954859 ko04024 cAMP signaling pathway 16/231 279/7206 0.0224192054905 ko05034 Alcoholism 14/231 238/7206 0.0239428556372 ko04916 Melanogenesis 10/231 142/7206 0.0249487658389 ko04022 cGMP-PKG signaling pathway 13/231 216/7206 0.0278382147961 ko04723 Retrograde endocannabinoid signaling 11/231 175/7206 0.0278648275619 ko04218 Cellular senescence 11/231 177/7206 0.0295503954337 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/231 1/7206 0.0320566194839 ko05033 Nicotine addiction 5/231 56/7206 0.0328954525384 ko05205 Proteoglycans in cancer 15/231 271/7206 0.0339104363423