ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	183/934	423/7206	4.47094446984e-58
ko05033	Nicotine addiction	48/934	56/7206	4.41628447216e-35
ko04724	Glutamatergic synapse	79/934	152/7206	1.29353300777e-31
ko04713	Circadian entrainment	67/934	136/7206	3.6505120723e-25
ko05032	Morphine addiction	58/934	110/7206	7.33475398702e-24
ko04728	Dopaminergic synapse	78/934	185/7206	1.26339705021e-23
ko04727	GABAergic synapse	57/934	110/7206	5.72341784618e-23
ko04024	cAMP signaling pathway	93/934	279/7206	2.17101946408e-19
ko04723	Retrograde endocannabinoid signaling	69/934	175/7206	4.60023478339e-19
ko04725	Cholinergic synapse	65/934	160/7206	8.07158833028e-19
ko04721	Synaptic vesicle cycle	42/934	80/7206	1.67189261812e-17
ko04911	Insulin secretion	51/934	117/7206	1.52268521628e-16
ko04020	Calcium signaling pathway	83/934	265/7206	1.46499362151e-15
ko04742	Taste transduction	34/934	61/7206	1.87819153182e-15
ko04726	Serotonergic synapse	52/934	137/7206	7.53593857045e-14
ko05031	Amphetamine addiction	40/934	91/7206	2.16836465382e-13
ko04921	Oxytocin signaling pathway	67/934	209/7206	4.20440540568e-13
ko04720	Long-term potentiation	41/934	99/7206	1.21174275313e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/934	205/7206	1.14959300178e-11
ko05030	Cocaine addiction	30/934	73/7206	1.66216430866e-09
ko04740	Olfactory transduction	31/934	80/7206	4.92035411702e-09
ko04970	Salivary secretion	33/934	95/7206	3.79073393375e-08
ko03040	Spliceosome	1/934	145/7206	5.74101792925e-08
ko04010	MAPK signaling pathway	75/934	321/7206	1.54572901454e-07
ko04925	Aldosterone synthesis and secretion	34/934	105/7206	1.68351896461e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/934	74/7206	2.09359956661e-07
ko04971	Gastric acid secretion	32/934	98/7206	3.13099878177e-07
ko05203	Viral carcinogenesis	11/934	277/7206	3.7226664508e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/934	79/7206	9.51220382753e-07
ko04360	Axon guidance	57/934	233/7206	1.28112692998e-06
ko05168	Herpes simplex infection	5/934	182/7206	2.8435737446e-06
ko04060	Cytokine-cytokine receptor interaction	6/934	191/7206	3.30785077968e-06
ko04745	Phototransduction - fly	16/934	38/7206	7.6363912619e-06
ko04730	Long-term depression	25/934	78/7206	8.8773120242e-06
ko05164	Influenza A	5/934	167/7206	1.15906335688e-05
ko04022	cGMP-PKG signaling pathway	51/934	216/7206	1.23813310628e-05
ko05322	Systemic lupus erythematosus	4/934	151/7206	1.33497645759e-05
ko04514	Cell adhesion molecules (CAMs)	35/934	130/7206	1.57948465419e-05
ko03013	RNA transport	6/934	166/7206	5.60527814245e-05
ko04120	Ubiquitin mediated proteolysis	4/934	138/7206	5.83851228948e-05
ko04924	Renin secretion	25/934	86/7206	6.32157839707e-05
ko04972	Pancreatic secretion	30/934	111/7206	7.81145672935e-05
ko04072	Phospholipase D signaling pathway	45/934	197/7206	9.52893295735e-05
ko04260	Cardiac muscle contraction	27/934	98/7206	9.96928481307e-05
ko05414	Dilated cardiomyopathy	29/934	112/7206	0.000177072453543
ko04966	Collecting duct acid secretion	11/934	26/7206	0.000197322341849
ko03008	Ribosome biogenesis in eukaryotes	1/934	79/7206	0.000318405431015
ko04141	Protein processing in endoplasmic reticulum	9/934	184/7206	0.000340202429778
ko04744	Phototransduction	13/934	36/7206	0.000348161195118
ko04540	Gap junction	31/934	128/7206	0.000450564423704
ko05169	Epstein-Barr virus infection	11/934	206/7206	0.000452085157103
ko04612	Antigen processing and presentation	1/934	77/7206	0.000477593860312
ko05162	Measles	4/934	120/7206	0.000506849625391
ko04750	Inflammatory mediator regulation of TRP channels	30/934	122/7206	0.000536620517141
ko04915	Estrogen signaling pathway	31/934	131/7206	0.000852338081924
ko04070	Phosphatidylinositol signaling system	27/934	112/7206	0.00100651476969
ko00240	Pyrimidine metabolism	4/934	110/7206	0.00144619355719
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/934	182/7206	0.0015694023609
ko04621	NOD-like receptor signaling pathway	8/934	157/7206	0.00162526852554
ko04110	Cell cycle	7/934	145/7206	0.0016375037993
ko05205	Proteoglycans in cancer	19/934	271/7206	0.00221017676765
ko04640	Hematopoietic cell lineage	1/934	64/7206	0.00235029319002
ko04350	TGF-beta signaling pathway	4/934	103/7206	0.00287372802933
ko04014	Ras signaling pathway	53/934	279/7206	0.00348715832407
ko04146	Peroxisome	3/934	89/7206	0.00373850293656
ko05140	Leishmaniasis	2/934	75/7206	0.00477771526803
ko04626	Plant-pathogen interaction	7/934	18/7206	0.00522262262898
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/934	14/7206	0.00555337390469
ko04064	NF-kappa B signaling pathway	4/934	96/7206	0.005664040373
ko05410	Hypertrophic cardiomyopathy (HCM)	23/934	100/7206	0.00613983461587
ko05110	Vibrio cholerae infection	16/934	63/7206	0.00702466921969
ko00480	Glutathione metabolism	1/934	55/7206	0.00772567415567
ko05161	Hepatitis B	11/934	173/7206	0.00791265034564
ko04015	Rap1 signaling pathway	51/934	278/7206	0.00822298736003
ko04964	Proximal tubule bicarbonate reclamation	9/934	29/7206	0.00884947664952
ko04912	GnRH signaling pathway	26/934	122/7206	0.00919054004608
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/934	59/7206	0.00954979948023
ko04930	Type II diabetes mellitus	14/934	54/7206	0.0123405609116
ko05166	HTLV-I infection	24/934	292/7206	0.0125051551586
ko04140	Autophagy - animal	11/934	164/7206	0.0131817471412
ko04550	Signaling pathways regulating pluripotency of stem cells	11/934	165/7206	0.0132565816355
ko00260	Glycine, serine and threonine metabolism	1/934	48/7206	0.0168193330488
ko04976	Bile secretion	18/934	80/7206	0.0175722386355
ko00330	Arginine and proline metabolism	2/934	61/7206	0.0199502128068
ko04330	Notch signaling pathway	2/934	62/7206	0.0204408397472
ko04214	Apoptosis - fly	3/934	72/7206	0.0209868999407
ko00310	Lysine degradation	3/934	73/7206	0.0212266419136
ko04722	Neurotrophin signaling pathway	31/934	160/7206	0.022784676602
ko05034	Alcoholism	43/934	238/7206	0.0234036763463
ko00071	Fatty acid degradation	1/934	45/7206	0.0248152999219
ko03420	Nucleotide excision repair	1/934	46/7206	0.0251484470724
ko04630	Jak-STAT signaling pathway	9/934	132/7206	0.0353274740155
ko04142	Lysosome	11/934	151/7206	0.0365863823423
ko03022	Basal transcription factors	1/934	44/7206	0.038421550857
ko05016	Huntington's disease	18/934	215/7206	0.0394003064095
ko01524	Platinum drug resistance	4/934	76/7206	0.0397812087181
ko05321	Inflammatory bowel disease (IBD)	2/934	56/7206	0.0422464775258
ko04071	Sphingolipid signaling pathway	30/934	162/7206	0.0432052772941
ko04658	Th1 and Th2 cell differentiation	6/934	96/7206	0.046671606001