ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	29/559	56/7206	3.19710657307e-18
ko04721	Synaptic vesicle cycle	34/559	80/7206	1.01725533934e-17
ko04724	Glutamatergic synapse	46/559	152/7206	1.3050633918e-16
ko04727	GABAergic synapse	36/559	110/7206	2.02343714845e-14
ko05032	Morphine addiction	35/559	110/7206	1.22829918119e-13
ko04728	Dopaminergic synapse	46/559	185/7206	4.3143819958e-13
ko04723	Retrograde endocannabinoid signaling	44/559	175/7206	9.43180322854e-13
ko04080	Neuroactive ligand-receptor interaction	73/559	423/7206	2.79829089501e-11
ko04713	Circadian entrainment	32/559	136/7206	7.79161113026e-09
ko04360	Axon guidance	43/559	233/7206	5.94308500003e-08
ko04911	Insulin secretion	27/559	117/7206	1.80353448233e-07
ko04024	cAMP signaling pathway	47/559	279/7206	2.65934964544e-07
ko04725	Cholinergic synapse	32/559	160/7206	4.51282224819e-07
ko04514	Cell adhesion molecules (CAMs)	27/559	130/7206	1.68074784336e-06
ko04261	Adrenergic signaling in cardiomyocytes	35/559	205/7206	7.18639811351e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	18/559	74/7206	9.37973633264e-06
ko04726	Serotonergic synapse	26/559	137/7206	1.47381495414e-05
ko05030	Cocaine addiction	17/559	73/7206	3.05498116342e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/559	14/7206	3.45153004933e-05
ko04010	MAPK signaling pathway	45/559	321/7206	9.78636112637e-05
ko05322	Systemic lupus erythematosus	1/559	151/7206	0.000146289231033
ko03040	Spliceosome	1/559	145/7206	0.000210356749868
ko04060	Cytokine-cytokine receptor interaction	3/559	191/7206	0.000285267771795
ko05203	Viral carcinogenesis	7/559	277/7206	0.000322426066882
ko05031	Amphetamine addiction	17/559	91/7206	0.00053399039497
ko04966	Collecting duct acid secretion	8/559	26/7206	0.000555369361285
ko01200	Carbon metabolism	1/559	128/7206	0.000652952455347
ko04720	Long-term potentiation	18/559	99/7206	0.000839512866726
ko05110	Vibrio cholerae infection	13/559	63/7206	0.000903359695809
ko04970	Salivary secretion	17/559	95/7206	0.00133317666131
ko03013	RNA transport	3/559	166/7206	0.00170493180464
ko04120	Ubiquitin mediated proteolysis	2/559	138/7206	0.00193867232564
ko04921	Oxytocin signaling pathway	29/559	209/7206	0.00220609437208
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/559	92/7206	0.00227419358751
ko04145	Phagosome	24/559	162/7206	0.00248242059446
ko04744	Phototransduction	8/559	36/7206	0.00539792217825
ko04964	Proximal tubule bicarbonate reclamation	7/559	29/7206	0.00563375986151
ko04972	Pancreatic secretion	17/559	111/7206	0.00621690722238
ko05168	Herpes simplex infection	5/559	182/7206	0.00709515939408
ko04260	Cardiac muscle contraction	15/559	98/7206	0.0113447287792
ko04022	cGMP-PKG signaling pathway	27/559	216/7206	0.0133055665134
ko01230	Biosynthesis of amino acids	1/559	85/7206	0.0136580539286
ko04146	Peroxisome	1/559	89/7206	0.0143569340616
ko04141	Protein processing in endoplasmic reticulum	6/559	184/7206	0.0169809383139
ko04071	Sphingolipid signaling pathway	21/559	162/7206	0.0170344723822
ko04140	Autophagy - animal	5/559	164/7206	0.0176285155042
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/559	8/7206	0.0193538928908
ko03018	RNA degradation	1/559	84/7206	0.0209537115096
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/559	59/7206	0.0227076224606
ko04350	TGF-beta signaling pathway	2/559	103/7206	0.0237006981676
ko05162	Measles	3/559	120/7206	0.0244067278546
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/559	15/7206	0.024547716769
ko04742	Taste transduction	10/559	61/7206	0.0250304736791
ko04211	Longevity regulating pathway	3/559	123/7206	0.0250431861749
ko04391	Hippo signaling pathway - fly	13/559	90/7206	0.0265462001712
ko04540	Gap junction	17/559	128/7206	0.028131574614
ko00010	Glycolysis / Gluconeogenesis	1/559	74/7206	0.0288442090867
ko04612	Antigen processing and presentation	1/559	77/7206	0.0293201311846
ko05161	Hepatitis B	6/559	173/7206	0.0300724191627
ko04978	Mineral absorption	7/559	40/7206	0.032184870098
ko05146	Amoebiasis	2/559	99/7206	0.0341928852871
ko05164	Influenza A	6/559	167/7206	0.039709978574
ko04973	Carbohydrate digestion and absorption	7/559	42/7206	0.0407862335817
ko04630	Jak-STAT signaling pathway	4/559	132/7206	0.0461947142489
ko00240	Pyrimidine metabolism	3/559	110/7206	0.0465043584177
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/559	182/7206	0.0480745003459