ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 39/264 145/7206 7.09719111427e-24 ko03030 DNA replication 14/264 38/7206 2.45268154465e-11 ko03008 Ribosome biogenesis in eukaryotes 19/264 79/7206 3.34125609586e-11 ko04110 Cell cycle 25/264 145/7206 6.20436843489e-11 ko03410 Base excision repair 10/264 38/7206 7.01092244341e-07 ko04218 Cellular senescence 21/264 177/7206 1.69998778202e-06 ko04080 Neuroactive ligand-receptor interaction 1/264 423/7206 3.02608599583e-06 ko03013 RNA transport 19/264 166/7206 9.15502456914e-06 ko00240 Pyrimidine metabolism 14/264 110/7206 4.36277255963e-05 ko05168 Herpes simplex infection 18/264 182/7206 0.000111878229373 ko03060 Protein export 6/264 23/7206 0.000136250260778 ko05212 Pancreatic cancer 11/264 83/7206 0.000200930552433 ko03420 Nucleotide excision repair 8/264 46/7206 0.000226966731362 ko05219 Bladder cancer 8/264 48/7206 0.000308060242719 ko04115 p53 signaling pathway 10/264 74/7206 0.000332663523953 ko05222 Small cell lung cancer 11/264 89/7206 0.000374315550824 ko04111 Cell cycle - yeast 11/264 90/7206 0.000412857715725 ko04113 Meiosis - yeast 9/264 70/7206 0.000951748279087 ko03430 Mismatch repair 5/264 22/7206 0.00100207642878 ko04020 Calcium signaling pathway 1/264 265/7206 0.00115872629374 ko05161 Hepatitis B 15/264 173/7206 0.0016357726529 ko03015 mRNA surveillance pathway 10/264 93/7206 0.00203269963648 ko03460 Fanconi anemia pathway 7/264 51/7206 0.00238099248747 ko05223 Non-small cell lung cancer 8/264 66/7206 0.00265604301479 ko05210 Colorectal cancer 9/264 86/7206 0.00404735984235 ko05203 Viral carcinogenesis 20/264 277/7206 0.00466948099606 ko01522 Endocrine resistance 11/264 124/7206 0.0056115612998 ko05206 MicroRNAs in cancer 14/264 177/7206 0.00657815046456 ko05215 Prostate cancer 10/264 111/7206 0.00729935977797 ko05214 Glioma 8/264 79/7206 0.00802578252436 ko05218 Melanoma 8/264 85/7206 0.012276846108 ko05220 Chronic myeloid leukemia 8/264 85/7206 0.012276846108 ko05166 HTLV-I infection 19/264 292/7206 0.0154486147002 ko03450 Non-homologous end-joining 3/264 15/7206 0.0159520594545 ko03440 Homologous recombination 5/264 41/7206 0.0162030921 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/264 191/7206 0.0290410061906 ko03018 RNA degradation 7/264 84/7206 0.0337379298144 ko05216 Thyroid cancer 4/264 34/7206 0.0344610388933 ko04139 Mitophagy - yeast 4/264 37/7206 0.045102614351 ko04141 Protein processing in endoplasmic reticulum 12/264 184/7206 0.0452184055745