ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 32/330 145/7206 4.07538072263e-14 ko03040 Spliceosome 31/330 145/7206 2.60748545492e-13 ko04111 Cell cycle - yeast 23/330 90/7206 7.10768785725e-12 ko05217 Basal cell carcinoma 16/330 68/7206 4.36501041403e-08 ko03410 Base excision repair 11/330 38/7206 6.2262248132e-07 ko04080 Neuroactive ligand-receptor interaction 2/330 423/7206 8.20491308707e-07 ko04340 Hedgehog signaling pathway 13/330 58/7206 1.49920299993e-06 ko04113 Meiosis - yeast 14/330 70/7206 2.54446082263e-06 ko03030 DNA replication 10/330 38/7206 5.31632591789e-06 ko03015 mRNA surveillance pathway 15/330 93/7206 1.79486640459e-05 ko05224 Breast cancer 21/330 174/7206 4.11577734416e-05 ko04020 Calcium signaling pathway 1/330 265/7206 7.23126168766e-05 ko05166 HTLV-I infection 29/330 292/7206 7.49445480308e-05 ko04550 Signaling pathways regulating pluripotency of stem cells 19/330 165/7206 0.00017963903606 ko04330 Notch signaling pathway 10/330 62/7206 0.000454054177895 ko04144 Endocytosis 4/330 342/7206 0.000758354914218 ko04310 Wnt signaling pathway 19/330 181/7206 0.000774260031035 ko04060 Cytokine-cytokine receptor interaction 1/330 191/7206 0.00232858730992 ko04612 Antigen processing and presentation 10/330 77/7206 0.00252270677255 ko04218 Cellular senescence 17/330 177/7206 0.00319162929413 ko05205 Proteoglycans in cancer 23/330 271/7206 0.00423830451989 ko05200 Pathways in cancer 36/330 492/7206 0.00487419072902 ko04910 Insulin signaling pathway 1/330 172/7206 0.00489027307717 ko04120 Ubiquitin mediated proteolysis 14/330 138/7206 0.0056047389997 ko05202 Transcriptional misregulation in cancer 17/330 188/7206 0.00685471027411 ko05418 Fluid shear stress and atherosclerosis 16/330 173/7206 0.00821601600396 ko04072 Phospholipase D signaling pathway 2/330 197/7206 0.00882321067589 ko04950 Maturity onset diabetes of the young 5/330 29/7206 0.0093661323347 ko05012 Parkinson's disease 1/330 155/7206 0.0103266177301 ko04725 Cholinergic synapse 1/330 160/7206 0.0108950631644 ko04360 Axon guidance 19/330 233/7206 0.0152275539225 ko03420 Nucleotide excision repair 6/330 46/7206 0.0175868978058 ko04022 cGMP-PKG signaling pathway 3/330 216/7206 0.0191211293378 ko04390 Hippo signaling pathway 16/330 188/7206 0.0191529381322 ko05222 Small cell lung cancer 9/330 89/7206 0.0201156849226 ko04931 Insulin resistance 1/330 137/7206 0.0215458470626 ko04726 Serotonergic synapse 1/330 137/7206 0.0215458470626 ko05130 Pathogenic Escherichia coli infection 8/330 77/7206 0.0239250208396 ko04723 Retrograde endocannabinoid signaling 2/330 175/7206 0.025522819625 ko05206 MicroRNAs in cancer 15/330 177/7206 0.0261014873754 ko04921 Oxytocin signaling pathway 3/330 209/7206 0.026805291012 ko03460 Fanconi anemia pathway 6/330 51/7206 0.0279801643558 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/330 26/7206 0.0290909940609 ko01522 Endocrine resistance 11/330 124/7206 0.0291662341722 ko04922 Glucagon signaling pathway 1/330 128/7206 0.0310338999472 ko04915 Estrogen signaling pathway 1/330 131/7206 0.0316459726056 ko05231 Choline metabolism in cancer 1/330 134/7206 0.0328236326547 ko00240 Pyrimidine metabolism 10/330 110/7206 0.034272466175 ko04911 Insulin secretion 1/330 117/7206 0.0444965724537 ko04211 Longevity regulating pathway 1/330 123/7206 0.0458487758579 ko00514 Other types of O-glycan biosynthesis 4/330 30/7206 0.046273809053 ko03022 Basal transcription factors 5/330 44/7206 0.0492128622