ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	60/536	152/7206	1.92781004241e-29
ko04080	Neuroactive ligand-receptor interaction	103/536	423/7206	1.9985010837e-29
ko05033	Nicotine addiction	37/536	56/7206	6.03663908927e-29
ko04721	Synaptic vesicle cycle	42/536	80/7206	5.93037999707e-27
ko04728	Dopaminergic synapse	55/536	185/7206	3.8678519596e-20
ko04727	GABAergic synapse	40/536	110/7206	2.16970057531e-18
ko05032	Morphine addiction	40/536	110/7206	2.16970057531e-18
ko04723	Retrograde endocannabinoid signaling	51/536	175/7206	2.5533409555e-18
ko04713	Circadian entrainment	41/536	136/7206	1.69594634962e-15
ko05031	Amphetamine addiction	31/536	91/7206	1.29403911724e-13
ko04911	Insulin secretion	34/536	117/7206	1.5361145121e-12
ko04725	Cholinergic synapse	40/536	160/7206	3.39772388212e-12
ko04024	cAMP signaling pathway	54/536	279/7206	3.05798085773e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	24/536	74/7206	2.56557762987e-10
ko04726	Serotonergic synapse	33/536	137/7206	8.09389243267e-10
ko05030	Cocaine addiction	23/536	73/7206	1.16599397177e-09
ko04720	Long-term potentiation	26/536	99/7206	7.52504436469e-09
ko04261	Adrenergic signaling in cardiomyocytes	40/536	205/7206	1.00202669743e-08
ko04742	Taste transduction	19/536	61/7206	4.08865301209e-08
ko04010	MAPK signaling pathway	52/536	321/7206	5.13739765886e-08
ko04921	Oxytocin signaling pathway	39/536	209/7206	5.552282911e-08
ko04966	Collecting duct acid secretion	12/536	26/7206	9.3400456836e-08
ko04744	Phototransduction	14/536	36/7206	1.10263620465e-07
ko04020	Calcium signaling pathway	42/536	265/7206	2.03355807043e-06
ko05110	Vibrio cholerae infection	17/536	63/7206	2.04510737232e-06
ko04970	Salivary secretion	21/536	95/7206	4.50552117026e-06
ko04730	Long-term depression	18/536	78/7206	1.15104763505e-05
ko05164	Influenza A	1/536	167/7206	6.62004796311e-05
ko04060	Cytokine-cytokine receptor interaction	2/536	191/7206	7.03511919407e-05
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/536	92/7206	0.000119240268797
ko04972	Pancreatic secretion	20/536	111/7206	0.000167645378404
ko05323	Rheumatoid arthritis	17/536	89/7206	0.00024824535101
ko04260	Cardiac muscle contraction	18/536	98/7206	0.000274582874956
ko03040	Spliceosome	1/536	145/7206	0.000310117901969
ko04145	Phagosome	25/536	162/7206	0.000394559941909
ko04120	Ubiquitin mediated proteolysis	1/536	138/7206	0.000447861162723
ko05203	Viral carcinogenesis	7/536	277/7206	0.000611492653007
ko05168	Herpes simplex infection	3/536	182/7206	0.000833540204759
ko04925	Aldosterone synthesis and secretion	18/536	105/7206	0.000937099325169
ko04971	Gastric acid secretion	17/536	98/7206	0.00128663804495
ko05322	Systemic lupus erythematosus	2/536	151/7206	0.00139320622312
ko04924	Renin secretion	15/536	86/7206	0.00151028193948
ko04540	Gap junction	20/536	128/7206	0.00166688284287
ko04514	Cell adhesion molecules (CAMs)	20/536	130/7206	0.00184234891737
ko05215	Prostate cancer	1/536	111/7206	0.00304936847437
ko04022	cGMP-PKG signaling pathway	28/536	216/7206	0.0034538151207
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/536	59/7206	0.00366970813372
ko04510	Focal adhesion	7/536	240/7206	0.00379756990778
ko04621	NOD-like receptor signaling pathway	3/536	157/7206	0.00487886719353
ko05010	Alzheimer's disease	26/536	202/7206	0.00589475492359
ko05205	Proteoglycans in cancer	9/536	271/7206	0.00624105401299
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/536	79/7206	0.00728204059999
ko05034	Alcoholism	29/536	238/7206	0.00781309181309
ko04626	Plant-pathogen interaction	5/536	18/7206	0.00848699775758
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/536	182/7206	0.00968743958148
ko05169	Epstein-Barr virus infection	6/536	206/7206	0.00969899917161
ko04141	Protein processing in endoplasmic reticulum	5/536	184/7206	0.00974230876465
ko05222	Small cell lung cancer	1/536	89/7206	0.0137952287275
ko04014	Ras signaling pathway	32/536	279/7206	0.0138488608501
ko00190	Oxidative phosphorylation	17/536	127/7206	0.0157941129112
ko04930	Type II diabetes mellitus	9/536	54/7206	0.0170284836027
ko04964	Proximal tubule bicarbonate reclamation	6/536	29/7206	0.0179358098063
ko04745	Phototransduction - fly	7/536	38/7206	0.0202399588477
ko04550	Signaling pathways regulating pluripotency of stem cells	5/536	165/7206	0.0239156157732
ko03013	RNA transport	5/536	166/7206	0.0239574579228
ko04110	Cell cycle	4/536	145/7206	0.0246264897685
ko05414	Dilated cardiomyopathy	15/536	112/7206	0.0266554504784
ko04072	Phospholipase D signaling pathway	23/536	197/7206	0.0271300914031
ko03008	Ribosome biogenesis in eukaryotes	1/536	79/7206	0.0291656931398
ko04140	Autophagy - animal	5/536	164/7206	0.0331169678119
ko04668	TNF signaling pathway	3/536	120/7206	0.0339997262228
ko04350	TGF-beta signaling pathway	2/536	103/7206	0.0342853097123
ko04962	Vasopressin-regulated water reabsorption	9/536	58/7206	0.0373259665377
ko05161	Hepatitis B	6/536	173/7206	0.0399177614541
ko04360	Axon guidance	26/536	233/7206	0.0407883010976
ko00310	Lysine degradation	1/536	73/7206	0.0420792272239
ko04915	Estrogen signaling pathway	16/536	131/7206	0.0428779869032
ko01524	Platinum drug resistance	1/536	76/7206	0.0435609197633
ko04612	Antigen processing and presentation	1/536	77/7206	0.044499398774
ko04931	Insulin resistance	4/536	137/7206	0.0461294223621
ko04064	NF-kappa B signaling pathway	2/536	96/7206	0.0470310192152
ko04976	Bile secretion	11/536	80/7206	0.0486413357795