ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	135/965	423/7206	1.79000586918e-24
ko04724	Glutamatergic synapse	67/965	152/7206	6.47826890286e-21
ko05033	Nicotine addiction	37/965	56/7206	8.82051400521e-20
ko04723	Retrograde endocannabinoid signaling	71/965	175/7206	1.33464527374e-19
ko04713	Circadian entrainment	60/965	136/7206	7.30341825044e-19
ko05032	Morphine addiction	49/965	110/7206	7.94655423955e-16
ko04728	Dopaminergic synapse	64/965	185/7206	7.97106303837e-14
ko04727	GABAergic synapse	46/965	110/7206	1.10018909888e-13
ko04921	Oxytocin signaling pathway	65/965	209/7206	1.46184172334e-11
ko04024	cAMP signaling pathway	79/965	279/7206	1.85072253367e-11
ko04020	Calcium signaling pathway	74/965	265/7206	1.64256288562e-10
ko04725	Cholinergic synapse	52/965	160/7206	3.35375593579e-10
ko04721	Synaptic vesicle cycle	33/965	80/7206	5.36291115445e-10
ko04911	Insulin secretion	41/965	117/7206	1.68518275349e-09
ko04726	Serotonergic synapse	45/965	137/7206	2.89860361458e-09
ko04742	Taste transduction	26/965	61/7206	1.63185530842e-08
ko04744	Phototransduction	19/965	36/7206	1.96307201631e-08
ko05203	Viral carcinogenesis	10/965	277/7206	3.97964596533e-08
ko05031	Amphetamine addiction	32/965	91/7206	9.55262815493e-08
ko05010	Alzheimer's disease	54/965	202/7206	2.88850302831e-07
ko03010	Ribosome	1/965	129/7206	2.89988717233e-07
ko04720	Long-term potentiation	32/965	99/7206	1.44815080667e-06
ko03040	Spliceosome	3/965	145/7206	3.01996788803e-06
ko04261	Adrenergic signaling in cardiomyocytes	52/965	205/7206	3.17280910451e-06
ko04970	Salivary secretion	30/965	95/7206	4.29428706592e-06
ko05164	Influenza A	5/965	167/7206	5.36847521129e-06
ko04022	cGMP-PKG signaling pathway	53/965	216/7206	6.37698448687e-06
ko04060	Cytokine-cytokine receptor interaction	7/965	191/7206	7.50913586294e-06
ko00190	Oxidative phosphorylation	36/965	127/7206	8.05387125522e-06
ko05322	Systemic lupus erythematosus	4/965	151/7206	8.97881494391e-06
ko04925	Aldosterone synthesis and secretion	31/965	105/7206	1.48714969298e-05
ko04110	Cell cycle	4/965	145/7206	1.90223781155e-05
ko05168	Herpes simplex infection	7/965	182/7206	2.14058599693e-05
ko05161	Hepatitis B	7/965	173/7206	6.02459215084e-05
ko05162	Measles	3/965	120/7206	6.40092606668e-05
ko05169	Epstein-Barr virus infection	10/965	206/7206	6.81730411904e-05
ko04710	Circadian rhythm	16/965	43/7206	7.23933554159e-05
ko04730	Long-term depression	23/965	78/7206	0.000158492051089
ko05030	Cocaine addiction	22/965	73/7206	0.000168307565596
ko00010	Glycolysis / Gluconeogenesis	22/965	74/7206	0.000199834415118
ko05014	Amyotrophic lateral sclerosis (ALS)	22/965	74/7206	0.000199834415118
ko04745	Phototransduction - fly	14/965	38/7206	0.000230288749839
ko04971	Gastric acid secretion	27/965	98/7206	0.000235340198034
ko04621	NOD-like receptor signaling pathway	7/965	157/7206	0.000320343011908
ko05166	HTLV-I infection	20/965	292/7206	0.00041752709837
ko03013	RNA transport	8/965	166/7206	0.000461676902341
ko05140	Leishmaniasis	1/965	75/7206	0.000468586084015
ko04120	Ubiquitin mediated proteolysis	6/965	138/7206	0.000589114483152
ko04964	Proximal tubule bicarbonate reclamation	11/965	29/7206	0.000809701843863
ko05215	Prostate cancer	4/965	111/7206	0.00102161481168
ko04630	Jak-STAT signaling pathway	6/965	132/7206	0.00114078093177
ko04922	Glucagon signaling pathway	30/965	128/7206	0.00157068612235
ko05012	Parkinson's disease	35/965	155/7206	0.00171386950926
ko05200	Pathways in cancer	44/965	492/7206	0.00199441075893
ko04612	Antigen processing and presentation	2/965	77/7206	0.00212228858811
ko03008	Ribosome biogenesis in eukaryotes	2/965	79/7206	0.00223862363459
ko04260	Cardiac muscle contraction	24/965	98/7206	0.00252369330328
ko04657	IL-17 signaling pathway	3/965	87/7206	0.00373659217082
ko04064	NF-kappa B signaling pathway	4/965	96/7206	0.00396574493585
ko04141	Protein processing in endoplasmic reticulum	12/965	184/7206	0.00409986319141
ko04972	Pancreatic secretion	26/965	111/7206	0.00438710586732
ko04740	Olfactory transduction	20/965	80/7206	0.00445709730516
ko04371	Apelin signaling pathway	37/965	177/7206	0.00493340801865
ko04210	Apoptosis	12/965	180/7206	0.00534934247655
ko04270	Vascular smooth muscle contraction	33/965	154/7206	0.00552969197345
ko04626	Plant-pathogen interaction	7/965	18/7206	0.00627543926227
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/965	14/7206	0.0065423616516
ko04010	MAPK signaling pathway	60/965	321/7206	0.00706238369575
ko04610	Complement and coagulation cascades	3/965	79/7206	0.00734958815021
ko04070	Phosphatidylinositol signaling system	25/965	112/7206	0.00774150919365
ko01200	Carbon metabolism	28/965	128/7206	0.00815092377662
ko04514	Cell adhesion molecules (CAMs)	28/965	130/7206	0.00896261785032
ko04510	Focal adhesion	19/965	240/7206	0.00911501624684
ko01230	Biosynthesis of amino acids	20/965	85/7206	0.0096338543262
ko01524	Platinum drug resistance	3/965	76/7206	0.0104169267483
ko04620	Toll-like receptor signaling pathway	5/965	100/7206	0.011018669131
ko00590	Arachidonic acid metabolism	1/965	52/7206	0.0119554734925
ko04330	Notch signaling pathway	2/965	62/7206	0.0136411547098
ko05205	Proteoglycans in cancer	23/965	271/7206	0.0139021549419
ko01521	EGFR tyrosine kinase inhibitor resistance	6/965	106/7206	0.0142843433527
ko04214	Apoptosis - fly	3/965	72/7206	0.0147214364828
ko05211	Renal cell carcinoma	5/965	96/7206	0.0149080094493
ko05220	Chronic myeloid leukemia	4/965	85/7206	0.0151664284735
ko03420	Nucleotide excision repair	1/965	46/7206	0.0166055025439
ko05145	Toxoplasmosis	8/965	126/7206	0.0168839046427
ko04966	Collecting duct acid secretion	8/965	26/7206	0.0169816177648
ko05219	Bladder cancer	1/965	48/7206	0.0169881980938
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/965	79/7206	0.0192897098416
ko05131	Shigellosis	4/965	82/7206	0.0210419032398
ko04810	Regulation of actin cytoskeleton	23/965	264/7206	0.0211686031718
ko00710	Carbon fixation in photosynthetic organisms	8/965	27/7206	0.0213773559826
ko05212	Pancreatic cancer	4/965	83/7206	0.0215204144427
ko00830	Retinol metabolism	11/965	42/7206	0.0218203500504
ko04660	T cell receptor signaling pathway	8/965	124/7206	0.0226516416496
ko04924	Renin secretion	19/965	86/7206	0.0244627977306
ko03022	Basal transcription factors	1/965	44/7206	0.0245704135666
ko05144	Malaria	1/965	45/7206	0.0251387027651
ko00620	Pyruvate metabolism	12/965	46/7206	0.0262145762164
ko04930	Type II diabetes mellitus	13/965	54/7206	0.0271570078853
ko05222	Small cell lung cancer	5/965	89/7206	0.0275310992176
ko05416	Viral myocarditis	2/965	55/7206	0.0279231348408
ko05321	Inflammatory bowel disease (IBD)	2/965	56/7206	0.0282181210298
ko05130	Pathogenic Escherichia coli infection	4/965	77/7206	0.0286519995805
ko04664	Fc epsilon RI signaling pathway	4/965	77/7206	0.0286519995805
ko04142	Lysosome	11/965	151/7206	0.028687978359
ko04668	TNF signaling pathway	8/965	120/7206	0.0295055460528
ko04750	Inflammatory mediator regulation of TRP channels	25/965	122/7206	0.0305704142808
ko00030	Pentose phosphate pathway	9/965	32/7206	0.031092148683
ko00240	Pyrimidine metabolism	7/965	110/7206	0.032804659831
ko05206	MicroRNAs in cancer	14/965	177/7206	0.0328581831443
ko04152	AMPK signaling pathway	31/965	161/7206	0.0343662209698
ko04658	Th1 and Th2 cell differentiation	6/965	96/7206	0.0346910050277
ko00362	Benzoate degradation	3/965	6/7206	0.03498755215
ko04150	mTOR signaling pathway	15/965	184/7206	0.0364593529208
ko04550	Signaling pathways regulating pluripotency of stem cells	13/965	165/7206	0.0366402484543
ko05133	Pertussis	5/965	87/7206	0.0377472745363
ko00680	Methane metabolism	9/965	34/7206	0.0384273540756
ko04115	p53 signaling pathway	4/965	74/7206	0.0392767170689
ko04011	MAPK signaling pathway - yeast	2/965	53/7206	0.0403925547931
ko00230	Purine metabolism	36/965	194/7206	0.0414409659668
ko00500	Starch and sucrose metabolism	9/965	35/7206	0.0433701000645