ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	34/490	80/7206	1.5775888752e-19
ko04080	Neuroactive ligand-receptor interaction	80/490	423/7206	4.93114354741e-18
ko05033	Nicotine addiction	27/490	56/7206	1.74183185398e-17
ko04724	Glutamatergic synapse	43/490	152/7206	1.61957822405e-16
ko04728	Dopaminergic synapse	46/490	185/7206	3.12236701506e-15
ko04727	GABAergic synapse	33/490	110/7206	9.67047001436e-14
ko04723	Retrograde endocannabinoid signaling	41/490	175/7206	9.20924011387e-13
ko04713	Circadian entrainment	35/490	136/7206	2.53495554455e-12
ko05032	Morphine addiction	30/490	110/7206	1.99548875132e-11
ko04966	Collecting duct acid secretion	14/490	26/7206	1.70610073294e-10
ko04911	Insulin secretion	29/490	117/7206	5.35220098456e-10
ko04725	Cholinergic synapse	34/490	160/7206	1.42328569771e-09
ko04024	cAMP signaling pathway	44/490	279/7206	1.35494369564e-07
ko04970	Salivary secretion	22/490	95/7206	2.48512383298e-07
ko04261	Adrenergic signaling in cardiomyocytes	35/490	205/7206	2.89943699215e-07
ko04726	Serotonergic synapse	27/490	137/7206	3.72487559796e-07
ko05031	Amphetamine addiction	20/490	91/7206	2.11801572511e-06
ko05110	Vibrio cholerae infection	16/490	63/7206	3.02097460861e-06
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/490	92/7206	1.00129894163e-05
ko04730	Long-term depression	17/490	78/7206	1.38749524737e-05
ko04744	Phototransduction	11/490	36/7206	1.62128575701e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	16/490	74/7206	2.75665350884e-05
ko04060	Cytokine-cytokine receptor interaction	1/490	191/7206	3.02403514111e-05
ko04972	Pancreatic secretion	20/490	111/7206	4.83325542989e-05
ko04964	Proximal tubule bicarbonate reclamation	9/490	29/7206	8.46023451856e-05
ko05030	Cocaine addiction	15/490	73/7206	9.12644413837e-05
ko04720	Long-term potentiation	18/490	99/7206	0.000101509488966
ko05164	Influenza A	1/490	167/7206	0.000144514295268
ko04145	Phagosome	24/490	162/7206	0.000352361301657
ko05322	Systemic lupus erythematosus	1/490	151/7206	0.000462595592021
ko05168	Herpes simplex infection	2/490	182/7206	0.000472200869649
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/490	59/7206	0.000503295824234
ko04514	Cell adhesion molecules (CAMs)	20/490	130/7206	0.000546158624856
ko04924	Renin secretion	15/490	86/7206	0.000602185964494
ko03040	Spliceosome	1/490	145/7206	0.000679232601656
ko04742	Taste transduction	12/490	61/7206	0.000691574841946
ko04745	Phototransduction - fly	9/490	38/7206	0.000794509088936
ko04022	cGMP-PKG signaling pathway	28/490	216/7206	0.000837527513053
ko04971	Gastric acid secretion	16/490	98/7206	0.000850797651859
ko05323	Rheumatoid arthritis	15/490	89/7206	0.000873532451909
ko04120	Ubiquitin mediated proteolysis	1/490	138/7206	0.000995273667021
ko00190	Oxidative phosphorylation	19/490	127/7206	0.00100060509275
ko04540	Gap junction	19/490	128/7206	0.00108214366334
ko05203	Viral carcinogenesis	7/490	277/7206	0.00212932552545
ko04020	Calcium signaling pathway	31/490	265/7206	0.00261906025439
ko05166	HTLV-I infection	8/490	292/7206	0.00279994125536
ko04921	Oxytocin signaling pathway	26/490	209/7206	0.00293450249569
ko05215	Prostate cancer	1/490	111/7206	0.00672614504894
ko04140	Autophagy - animal	3/490	164/7206	0.0068064455342
ko03013	RNA transport	3/490	166/7206	0.00701843929879
ko04260	Cardiac muscle contraction	14/490	98/7206	0.00713402623868
ko05161	Hepatitis B	4/490	173/7206	0.013510232591
ko04371	Apelin signaling pathway	21/490	177/7206	0.0141832919418
ko05010	Alzheimer's disease	23/490	202/7206	0.0148070336164
ko04925	Aldosterone synthesis and secretion	14/490	105/7206	0.016351743394
ko04668	TNF signaling pathway	2/490	120/7206	0.0167752305791
ko04660	T cell receptor signaling pathway	2/490	124/7206	0.0173301099025
ko04976	Bile secretion	11/490	80/7206	0.0222571885623
ko04510	Focal adhesion	8/490	240/7206	0.0262227912037
ko05220	Chronic myeloid leukemia	1/490	85/7206	0.0295090615517
ko04657	IL-17 signaling pathway	1/490	87/7206	0.0297625336295
ko04626	Plant-pathogen interaction	4/490	18/7206	0.0301098308131
ko04010	MAPK signaling pathway	32/490	321/7206	0.0301397402722
ko05222	Small cell lung cancer	1/490	89/7206	0.0305641598657
ko04630	Jak-STAT signaling pathway	3/490	132/7206	0.0345945247005
ko04621	NOD-like receptor signaling pathway	4/490	157/7206	0.0349334608251
ko04014	Ras signaling pathway	28/490	279/7206	0.0380120775031
ko04610	Complement and coagulation cascades	1/490	79/7206	0.0426223758668
ko04914	Progesterone-mediated oocyte maturation	2/490	104/7206	0.0471790462405
ko01522	Endocrine resistance	3/490	124/7206	0.0471961004498
ko04211	Longevity regulating pathway	3/490	123/7206	0.0472249789077
ko05169	Epstein-Barr virus infection	7/490	206/7206	0.0485723932955