ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 15/146 79/7206 3.42773639321e-11 ko04911 Insulin secretion 13/146 117/7206 5.76112072681e-07 ko05033 Nicotine addiction 8/146 56/7206 1.46286410243e-05 ko04964 Proximal tubule bicarbonate reclamation 6/146 29/7206 2.01810686091e-05 ko04970 Salivary secretion 9/146 95/7206 0.000120040311443 ko04721 Synaptic vesicle cycle 8/146 80/7206 0.00019817599543 ko04976 Bile secretion 8/146 80/7206 0.00019817599543 ko04725 Cholinergic synapse 11/146 160/7206 0.00037915491678 ko04080 Neuroactive ligand-receptor interaction 20/146 423/7206 0.000447242271826 ko04961 Endocrine and other factor-regulated calcium reabsorption 6/146 59/7206 0.00116187772028 ko04713 Circadian entrainment 9/146 136/7206 0.00169426720212 ko02024 Quorum sensing 3/146 15/7206 0.00310031466434 ko04724 Glutamatergic synapse 9/146 152/7206 0.00361213005951 ko05150 Staphylococcus aureus infection 4/146 36/7206 0.00575704784237 ko04727 GABAergic synapse 7/146 110/7206 0.00679573488688 ko04972 Pancreatic secretion 7/146 111/7206 0.00713318496818 ko04978 Mineral absorption 4/146 40/7206 0.00839234452483 ko04960 Aldosterone-regulated sodium reabsorption 4/146 41/7206 0.00915610826996 ko04728 Dopaminergic synapse 9/146 185/7206 0.0126221975311 ko04974 Protein digestion and absorption 6/146 96/7206 0.0129984936671 ko04024 cAMP signaling pathway 12/146 279/7206 0.0137985091499 ko04971 Gastric acid secretion 6/146 98/7206 0.0142842852775 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 3/146 26/7206 0.0150606055935 ko05030 Cocaine addiction 5/146 73/7206 0.0158925325888 ko05014 Amyotrophic lateral sclerosis (ALS) 5/146 74/7206 0.0167740201616 ko04950 Maturity onset diabetes of the young 3/146 29/7206 0.020255246942 ko04730 Long-term depression 5/146 78/7206 0.0206237203904 ko04723 Retrograde endocannabinoid signaling 8/146 175/7206 0.0254815563476 ko04940 Type I diabetes mellitus 3/146 32/7206 0.0263153630628 ko04924 Renin secretion 5/146 86/7206 0.0299572134687 ko04918 Thyroid hormone synthesis 5/146 86/7206 0.0299572134687 ko00770 Pantothenate and CoA biosynthesis 2/146 14/7206 0.0316328881939 ko00430 Taurine and hypotaurine metabolism 2/146 14/7206 0.0316328881939 ko00410 beta-Alanine metabolism 3/146 35/7206 0.0332395783344 ko04920 Adipocytokine signaling pathway 5/146 89/7206 0.0340455388994 ko05031 Amphetamine addiction 5/146 91/7206 0.0369548223585 ko04022 cGMP-PKG signaling pathway 9/146 216/7206 0.0422532247793 ko05020 Prion diseases 3/146 40/7206 0.0466659878639