ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 7/419 20/7206 8.54515729644e-05 ko04710 Circadian rhythm 10/419 43/7206 0.000134237410427 ko04060 Cytokine-cytokine receptor interaction 24/419 191/7206 0.000390277197521 ko00350 Tyrosine metabolism 8/419 33/7206 0.000467477912464 ko00592 alpha-Linolenic acid metabolism 6/419 19/7206 0.000528436694586 ko04146 Peroxisome 14/419 89/7206 0.00056045170903 ko04610 Complement and coagulation cascades 13/419 79/7206 0.000563165395503 ko05034 Alcoholism 3/419 238/7206 0.000618310042842 ko00590 Arachidonic acid metabolism 10/419 52/7206 0.000692129281498 ko04650 Natural killer cell mediated cytotoxicity 14/419 97/7206 0.00134248699948 ko05340 Primary immunodeficiency 7/419 30/7206 0.00135231149373 ko00360 Phenylalanine metabolism 5/419 17/7206 0.00224110967253 ko03040 Spliceosome 1/419 145/7206 0.00333800824169 ko04110 Cell cycle 1/419 145/7206 0.00333800824169 ko05150 Staphylococcus aureus infection 7/419 36/7206 0.00410122777787 ko05321 Inflammatory bowel disease (IBD) 9/419 56/7206 0.00460303173995 ko04672 Intestinal immune network for IgA production 7/419 37/7206 0.00481103387185 ko05145 Toxoplasmosis 15/419 126/7206 0.00666375033223 ko04390 Hippo signaling pathway 3/419 188/7206 0.00685658602834 ko03010 Ribosome 1/419 129/7206 0.00689668006991 ko04137 Mitophagy - animal 11/419 82/7206 0.00751022686405 ko00330 Arginine and proline metabolism 9/419 61/7206 0.00815795805541 ko00140 Steroid hormone biosynthesis 7/419 41/7206 0.00860258197148 ko04611 Platelet activation 18/419 163/7206 0.00958892862969 ko00051 Fructose and mannose metabolism 7/419 42/7206 0.00982129278626 ko05140 Leishmaniasis 10/419 75/7206 0.011024205791 ko04658 Th1 and Th2 cell differentiation 12/419 96/7206 0.0124201366135 ko05203 Viral carcinogenesis 7/419 277/7206 0.0125625805761 ko04630 Jak-STAT signaling pathway 15/419 132/7206 0.0125854407662 ko04380 Osteoclast differentiation 15/419 134/7206 0.013594840726 ko04621 NOD-like receptor signaling pathway 17/419 157/7206 0.0138913751776 ko04010 MAPK signaling pathway 9/419 321/7206 0.0143800233195 ko00950 Isoquinoline alkaloid biosynthesis 3/419 10/7206 0.0172349439604 ko04660 T cell receptor signaling pathway 14/419 124/7206 0.0174429668214 ko03013 RNA transport 3/419 166/7206 0.018445642577 ko00982 Drug metabolism - cytochrome P450 6/419 37/7206 0.0186716846378 ko04068 FoxO signaling pathway 17/419 167/7206 0.0272018090322 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/419 5/7206 0.0299948109406 ko04659 Th17 cell differentiation 12/419 106/7206 0.0323439174672 ko00830 Retinol metabolism 6/419 42/7206 0.033066308103 ko04724 Glutamatergic synapse 3/419 152/7206 0.0350454270164 ko04662 B cell receptor signaling pathway 10/419 88/7206 0.0358376755985 ko00480 Glutathione metabolism 7/419 55/7206 0.0388507970408 ko00362 Benzoate degradation 2/419 6/7206 0.0432817950317 ko04664 Fc epsilon RI signaling pathway 9/419 77/7206 0.0433735384089 ko05164 Influenza A 16/419 167/7206 0.0434325788221 ko03015 mRNA surveillance pathway 1/419 93/7206 0.0435258656878 ko05224 Breast cancer 4/419 174/7206 0.0470166285447 ko04723 Retrograde endocannabinoid signaling 4/419 175/7206 0.047340681016 ko05330 Allograft rejection 4/419 24/7206 0.0475057273705 ko00220 Arginine biosynthesis 4/419 24/7206 0.0475057273705 ko01522 Endocrine resistance 2/419 124/7206 0.049169101485